Project measure / variable:   HMDPpheno6   IV_Gly

ID, description, units MPD:50171   IV_Gly   liver isovalerylglycine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver isovalerylglycine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means128074   None
Median of the strain means116207   None
SD of the strain means± 52204
Coefficient of variation (CV)0.408
Min–max range of strain means47016   –   321017   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 60487078455.5843 2880337069.3135 1.9264 0.0432
Residuals 34 50836232223.6655 1495183300.696


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 144715.0 0.0   1   0.0 0.0 144715.0, 144715.0 0.32
A/J m 119855.0 22229.0   2   15718.0 0.185 104136.0, 135573.0 -0.16
AKR/J m 62998.0 0.0   1   0.0 0.0 62998.0, 62998.0 -1.25
AXB10/PgnJ m 150114.0 0.0   1   0.0 0.0 150114.0, 150114.0 0.42
AXB12/PgnJ m 74162.0 0.0   1   0.0 0.0 74162.0, 74162.0 -1.03
AXB13/PgnJ m 89876.0 0.0   1   0.0 0.0 89876.0, 89876.0 -0.73
AXB15/PgnJ m 179549.0 0.0   1   0.0 0.0 179549.0, 179549.0 0.99
AXB19a/PgnJ m 266214.0 0.0   1   0.0 0.0 266214.0, 266214.0 2.65
AXB19b/PgnJ m 118197.0 3251.0   2   2299.0 0.0275 115898.0, 120496.0 -0.19
AXB19/PgnJ m 145866.0 0.0   1   0.0 0.0 145866.0, 145866.0 0.34
AXB1/PgnJ m 104427.0 0.0   1   0.0 0.0 104427.0, 104427.0 -0.45
AXB23/PgnJ m 100305.0 0.0   1   0.0 0.0 100305.0, 100305.0 -0.53
AXB24/PgnJ m 82728.0 45818.0   2   32398.0 0.554 50330.0, 115126.0 -0.87
AXB2/PgnJ m 114454.0 0.0   1   0.0 0.0 114454.0, 114454.0 -0.26
AXB4/PgnJ m 150648.0 0.0   1   0.0 0.0 150648.0, 150648.0 0.43
AXB5/PgnJ m 119892.0 0.0   1   0.0 0.0 119892.0, 119892.0 -0.16
AXB6/PgnJ m 131593.0 0.0   1   0.0 0.0 131593.0, 131593.0 0.07
AXB8/PgnJ m 160966.0 0.0   1   0.0 0.0 160966.0, 160966.0 0.63
BALB/cJ m 102225.0 15955.0   3 9211.0 0.156 83991.0, 113620.0 -0.5
BTBR T+ Itpr3tf/J m 118643.0 0.0   1   0.0 0.0 118643.0, 118643.0 -0.18
BUB/BnJ m 146483.0 0.0   1   0.0 0.0 146483.0, 146483.0 0.35
BXA11/PgnJ m 51740.0 0.0   1   0.0 0.0 51740.0, 51740.0 -1.46
BXA12/PgnJ m 101610.0 0.0   1   0.0 0.0 101610.0, 101610.0 -0.51
BXA13/PgnJ m 117860.0 0.0   1   0.0 0.0 117860.0, 117860.0 -0.2
BXA14/PgnJ m 129976.0 0.0   1   0.0 0.0 129976.0, 129976.0 0.04
BXA16/PgnJ m 185934.0 94024.0   2   66485.0 0.506 119449.0, 252419.0 1.11
BXA1/PgnJ m 76934.0 0.0   1   0.0 0.0 76934.0, 76934.0 -0.98
BXA24/PgnJ m 99993.0 0.0   1   0.0 0.0 99993.0, 99993.0 -0.54
BXA25/PgnJ m 92332.0 0.0   1   0.0 0.0 92332.0, 92332.0 -0.68
BXA26/PgnJ m 141387.0 0.0   1   0.0 0.0 141387.0, 141387.0 0.26
BXA2/PgnJ m 98909.0 0.0   1   0.0 0.0 98909.0, 98909.0 -0.56
BXA4/PgnJ m 178236.0 0.0   1   0.0 0.0 178236.0, 178236.0 0.96
BXA7/PgnJ m 77125.0 0.0   1   0.0 0.0 77125.0, 77125.0 -0.98
BXA8/PgnJ m 109815.0 0.0   1   0.0 0.0 109815.0, 109815.0 -0.35
BXD11/TyJ m 103622.0 0.0   1   0.0 0.0 103622.0, 103622.0 -0.47
BXD12/TyJ m 126588.0 0.0   1   0.0 0.0 126588.0, 126588.0 -0.03
BXD13/TyJ m 142369.0 0.0   1   0.0 0.0 142369.0, 142369.0 0.27
BXD14/TyJ m 221342.0 0.0   1   0.0 0.0 221342.0, 221342.0 1.79
BXD15/TyJ m 130118.0 0.0   1   0.0 0.0 130118.0, 130118.0 0.04
BXD18/TyJ m 123300.0 0.0   1   0.0 0.0 123300.0, 123300.0 -0.09
BXD19/TyJ m 179142.0 20371.0   2   14404.0 0.114 164737.0, 193546.0 0.98
BXD1/TyJ m 117577.0 0.0   1   0.0 0.0 117577.0, 117577.0 -0.2
BXD20/TyJ m 119467.0 0.0   1   0.0 0.0 119467.0, 119467.0 -0.16
BXD21/TyJ m 114565.0 0.0   1   0.0 0.0 114565.0, 114565.0 -0.26
BXD22/TyJ m 83077.0 0.0   1   0.0 0.0 83077.0, 83077.0 -0.86
BXD24/TyJ m 208823.0 0.0   1   0.0 0.0 208823.0, 208823.0 1.55
BXD24/TyJ-Cep290rd16/J m 192968.0 0.0   1   0.0 0.0 192968.0, 192968.0 1.24
BXD28/TyJ m 89581.0 15989.0   2   11306.0 0.178 78275.0, 100886.0 -0.74
BXD29-Tlr4lps-2J/J m 185474.0 0.0   1   0.0 0.0 185474.0, 185474.0 1.1
BXD2/TyJ m 104595.0 0.0   1   0.0 0.0 104595.0, 104595.0 -0.45
BXD32/TyJ m 116486.0 0.0   1   0.0 0.0 116486.0, 116486.0 -0.22
BXD33/TyJ m 232718.0 0.0   1   0.0 0.0 232718.0, 232718.0 2.0
BXD34/TyJ m 73730.0 0.0   1   0.0 0.0 73730.0, 73730.0 -1.04
BXD36/TyJ m 234554.0 0.0   1   0.0 0.0 234554.0, 234554.0 2.04
BXD38/TyJ m 193273.0 0.0   1   0.0 0.0 193273.0, 193273.0 1.25
BXD39/TyJ m 91205.0 0.0   1   0.0 0.0 91205.0, 91205.0 -0.71
BXD40/TyJ m 246784.0 0.0   1   0.0 0.0 246784.0, 246784.0 2.27
BXD42/TyJ m 189720.0 0.0   1   0.0 0.0 189720.0, 189720.0 1.18
BXD5/TyJ m 115082.0 0.0   1   0.0 0.0 115082.0, 115082.0 -0.25
BXD6/TyJ m 89073.0 0.0   1   0.0 0.0 89073.0, 89073.0 -0.75
BXD8/TyJ m 134061.0 0.0   1   0.0 0.0 134061.0, 134061.0 0.11
BXD9/TyJ m 146341.0 0.0   1   0.0 0.0 146341.0, 146341.0 0.35
BXH10/TyJ m 116039.0 0.0   1   0.0 0.0 116039.0, 116039.0 -0.23
BXH19/TyJ m 47016.0 0.0   1   0.0 0.0 47016.0, 47016.0 -1.55
BXH20/KccJ m 130426.0 0.0   1   0.0 0.0 130426.0, 130426.0 0.05
BXH22/KccJ m 58777.0 0.0   1   0.0 0.0 58777.0, 58777.0 -1.33
BXH2/TyJ m 86992.0 0.0   1   0.0 0.0 86992.0, 86992.0 -0.79
BXH4/TyJ m 111628.0 16150.0   2   11420.0 0.145 100208.0, 123048.0 -0.32
BXH6/TyJ m 239324.0 0.0   1   0.0 0.0 239324.0, 239324.0 2.13
BXH7/TyJ m 212327.0 0.0   1   0.0 0.0 212327.0, 212327.0 1.61
BXH8/TyJ m 103542.0 0.0   1   0.0 0.0 103542.0, 103542.0 -0.47
BXH9/TyJ m 101170.0 0.0   1   0.0 0.0 101170.0, 101170.0 -0.52
C3H/HeJ m 179314.0 26795.0   2   18947.0 0.149 160367.0, 198261.0 0.98
C57BL/6J m 130789.0 26187.0   5 11711.0 0.2 110981.0, 175915.0 0.05
C57L/J m 67135.0 0.0   1   0.0 0.0 67135.0, 67135.0 -1.17
C58/J m 116375.0 0.0   1   0.0 0.0 116375.0, 116375.0 -0.22
CAST/EiJ m 77519.0 0.0   1   0.0 0.0 77519.0, 77519.0 -0.97
CBA/J m 151937.0 0.0   1   0.0 0.0 151937.0, 151937.0 0.46
CE/J m 148611.0 0.0   1   0.0 0.0 148611.0, 148611.0 0.39
CXB11/HiAJ m 70231.0 27554.0   2   19484.0 0.392 50747.0, 89715.0 -1.11
CXB12/HiAJ m 112652.0 4471.0   2   3162.0 0.0397 109491.0, 115814.0 -0.3
CXB13/HiAJ m 146953.0 101411.0   3 58550.0 0.69 79656.0, 263593.0 0.36
CXB1/ByJ m 97636.0 39069.0   3 22556.0 0.4 63033.0, 140005.0 -0.58
CXB2/ByJ m 111178.0 42628.0   3 24611.0 0.383 77904.0, 159229.0 -0.32
CXB3/ByJ m 113330.0 1890.0   2   1336.0 0.0167 111994.0, 114666.0 -0.28
CXB4/ByJ m 49804.0 22215.0   2   15708.0 0.446 34096.0, 65512.0 -1.5
CXB6/ByJ m 109287.0 31075.0   3 17941.0 0.284 85711.0, 144501.0 -0.36
CXB7/ByJ m 99288.0 23240.0   2   16433.0 0.234 82855.0, 115721.0 -0.55
CXB8/HiAJ m 124030.0 10789.0   3 6229.0 0.087 112486.0, 133860.0 -0.08
CXB9/HiAJ m 81902.0 29178.0   3 16846.0 0.356 60904.0, 115219.0 -0.88
DBA/2J m 161928.0 22742.0   4 11371.0 0.14 131047.0, 184848.0 0.65
FVB/NJ m 103004.0 0.0   1   0.0 0.0 103004.0, 103004.0 -0.48
I/LnJ m 151517.0 0.0   1   0.0 0.0 151517.0, 151517.0 0.45
KK/HlJ m 107057.0 0.0   1   0.0 0.0 107057.0, 107057.0 -0.4
LG/J m 89997.0 0.0   1   0.0 0.0 89997.0, 89997.0 -0.73
LP/J m 154327.0 0.0   1   0.0 0.0 154327.0, 154327.0 0.5
MA/MyJ m 62193.0 0.0   1   0.0 0.0 62193.0, 62193.0 -1.26
NOD/ShiLtJ m 102892.0 0.0   1   0.0 0.0 102892.0, 102892.0 -0.48
NON/ShiLtJ m 321017.0 0.0   1   0.0 0.0 321017.0, 321017.0 3.7
NZW/LacJ m 92873.0 0.0   1   0.0 0.0 92873.0, 92873.0 -0.67
PL/J m 105222.0 0.0   1   0.0 0.0 105222.0, 105222.0 -0.44
RIIIS/J m 85490.0 0.0   1   0.0 0.0 85490.0, 85490.0 -0.82
SEA/GnJ m 101491.0 0.0   1   0.0 0.0 101491.0, 101491.0 -0.51
SJL/J m 66222.0 0.0   1   0.0 0.0 66222.0, 66222.0 -1.18
SM/J m 304543.0 0.0   1   0.0 0.0 304543.0, 304543.0 3.38
SWR/J m 119418.0 0.0   1   0.0 0.0 119418.0, 119418.0 -0.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 119854.7 27342.1223 175420.5779 64288.8221
AXB19b/PgnJ m 118196.75 27342.1223 173762.6279 62630.8721
AXB24/PgnJ m 82728.25 27342.1223 138294.1279 27162.3721
BALB/cJ m 102224.9 22324.7494 147594.2493 56855.5507
BXA16/PgnJ m 185934.0 27342.1223 241499.8779 130368.1221
BXD19/TyJ m 179141.55 27342.1223 234707.4279 123575.6721
BXD28/TyJ m 89580.75 27342.1223 145146.6279 34014.8721
BXH4/TyJ m 111627.8 27342.1223 167193.6779 56061.9221
C3H/HeJ m 179313.9 27342.1223 234879.7779 123748.0221
C57BL/6J m 130788.62 17292.6765 165931.5668 95645.6732
CXB11/HiAJ m 70231.0 27342.1223 125796.8779 14665.1221
CXB12/HiAJ m 112652.3 27342.1223 168218.1779 57086.4221
CXB13/HiAJ m 146953.2333 22324.7494 192322.5826 101583.884
CXB1/ByJ m 97635.8 22324.7494 143005.1493 52266.4507
CXB2/ByJ m 111178.3333 22324.7494 156547.6826 65808.984
CXB3/ByJ m 113329.75 27342.1223 168895.6279 57763.8721
CXB4/ByJ m 49803.6 27342.1223 105369.4779 0.0
CXB6/ByJ m 109286.9667 22324.7494 154656.316 63917.6174
CXB7/ByJ m 99287.75 27342.1223 154853.6279 43721.8721
CXB8/HiAJ m 124029.7 22324.7494 169399.0493 78660.3507
CXB9/HiAJ m 81901.9 22324.7494 127271.2493 36532.5507
DBA/2J m 161928.025 19333.8001 201219.034 122637.016




  GWAS USING LINEAR MIXED MODELS