Project measure / variable:   HMDPpheno6   kynurenate

ID, description, units MPD:50156   kynurenate   liver kynurenate (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   105 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver kynurenate (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested105 strains
Mean of the strain means20703   None
Median of the strain means18376   None
SD of the strain means± 13255
Coefficient of variation (CV)0.640
Min–max range of strain means4292   –   89346   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 19 3104740736.611 163407407.1901 5.3539 < 0.0001
Residuals 31 946155292.2388 30521138.4593


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 14150.0 0.0   1   0.0 0.0 14150.0, 14150.0 -0.49
A/J m 9053.0 976.0   2   690.0 0.108 8362.0, 9743.0 -0.88
AKR/J m 19419.0 0.0   1   0.0 0.0 19419.0, 19419.0 -0.1
AXB10/PgnJ m 13717.0 0.0   1   0.0 0.0 13717.0, 13717.0 -0.53
AXB12/PgnJ m 10940.0 0.0   1   0.0 0.0 10940.0, 10940.0 -0.74
AXB13/PgnJ m 5786.0 0.0   1   0.0 0.0 5786.0, 5786.0 -1.13
AXB15/PgnJ m 16249.0 0.0   1   0.0 0.0 16249.0, 16249.0 -0.34
AXB19a/PgnJ m 19319.0 0.0   1   0.0 0.0 19319.0, 19319.0 -0.1
AXB19b/PgnJ m 19009.0 3548.0   2   2509.0 0.187 16501.0, 21518.0 -0.13
AXB19/PgnJ m 14141.0 0.0   1   0.0 0.0 14141.0, 14141.0 -0.5
AXB1/PgnJ m 17475.0 0.0   1   0.0 0.0 17475.0, 17475.0 -0.24
AXB23/PgnJ m 18474.0 0.0   1   0.0 0.0 18474.0, 18474.0 -0.17
AXB24/PgnJ m 6635.0 7.5   2   5.3 0.00113 6630.0, 6640.0 -1.06
AXB2/PgnJ m 15626.0 0.0   1   0.0 0.0 15626.0, 15626.0 -0.38
AXB4/PgnJ m 15565.0 0.0   1   0.0 0.0 15565.0, 15565.0 -0.39
AXB5/PgnJ m 5078.0 0.0   1   0.0 0.0 5078.0, 5078.0 -1.18
AXB6/PgnJ m 21327.0 0.0   1   0.0 0.0 21327.0, 21327.0 0.05
AXB8/PgnJ m 28716.0 0.0   1   0.0 0.0 28716.0, 28716.0 0.6
BALB/cJ m 13056.0 5661.0   3 3268.0 0.434 6562.0, 16954.0 -0.58
BTBR T+ Itpr3tf/J m 19796.0 0.0   1   0.0 0.0 19796.0, 19796.0 -0.07
BUB/BnJ m 18877.0 0.0   1   0.0 0.0 18877.0, 18877.0 -0.14
BXA11/PgnJ m 9664.0 0.0   1   0.0 0.0 9664.0, 9664.0 -0.83
BXA12/PgnJ m 28149.0 0.0   1   0.0 0.0 28149.0, 28149.0 0.56
BXA13/PgnJ m 17542.0 0.0   1   0.0 0.0 17542.0, 17542.0 -0.24
BXA14/PgnJ m 16128.0 0.0   1   0.0 0.0 16128.0, 16128.0 -0.35
BXA16/PgnJ m 20647.0 17029.0   2   12041.0 0.825 8605.0, 32688.0 0.0
BXA1/PgnJ m 5774.0 0.0   1   0.0 0.0 5774.0, 5774.0 -1.13
BXA24/PgnJ m 14126.0 0.0   1   0.0 0.0 14126.0, 14126.0 -0.5
BXA25/PgnJ m 12521.0 0.0   1   0.0 0.0 12521.0, 12521.0 -0.62
BXA26/PgnJ m 17886.0 0.0   1   0.0 0.0 17886.0, 17886.0 -0.21
BXA2/PgnJ m 4498.0 0.0   1   0.0 0.0 4498.0, 4498.0 -1.22
BXA4/PgnJ m 20151.0 0.0   1   0.0 0.0 20151.0, 20151.0 -0.04
BXA7/PgnJ m 6670.0 0.0   1   0.0 0.0 6670.0, 6670.0 -1.06
BXA8/PgnJ m 10210.0 0.0   1   0.0 0.0 10210.0, 10210.0 -0.79
BXD11/TyJ m 21644.0 0.0   1   0.0 0.0 21644.0, 21644.0 0.07
BXD12/TyJ m 29037.0 0.0   1   0.0 0.0 29037.0, 29037.0 0.63
BXD13/TyJ m 15345.0 0.0   1   0.0 0.0 15345.0, 15345.0 -0.4
BXD14/TyJ m 18376.0 0.0   1   0.0 0.0 18376.0, 18376.0 -0.18
BXD15/TyJ m 29186.0 0.0   1   0.0 0.0 29186.0, 29186.0 0.64
BXD18/TyJ m 22480.0 0.0   1   0.0 0.0 22480.0, 22480.0 0.13
BXD19/TyJ m 35313.0 2545.0   2   1799.0 0.0721 33514.0, 37113.0 1.1
BXD1/TyJ m 26763.0 0.0   1   0.0 0.0 26763.0, 26763.0 0.46
BXD20/TyJ m 52229.0 0.0   1   0.0 0.0 52229.0, 52229.0 2.38
BXD21/TyJ m 29562.0 0.0   1   0.0 0.0 29562.0, 29562.0 0.67
BXD22/TyJ m 11882.0 0.0   1   0.0 0.0 11882.0, 11882.0 -0.67
BXD24/TyJ m 19000.0 0.0   1   0.0 0.0 19000.0, 19000.0 -0.13
BXD24/TyJ-Cep290rd16/J m 42578.0 0.0   1   0.0 0.0 42578.0, 42578.0 1.65
BXD28/TyJ m 10806.0 776.0   2   549.0 0.0718 10257.0, 11354.0 -0.75
BXD29-Tlr4lps-2J/J m 42341.0 0.0   1   0.0 0.0 42341.0, 42341.0 1.63
BXD2/TyJ m 11640.0 0.0   1   0.0 0.0 11640.0, 11640.0 -0.68
BXD32/TyJ m 24514.0 0.0   1   0.0 0.0 24514.0, 24514.0 0.29
BXD33/TyJ m 39798.0 0.0   1   0.0 0.0 39798.0, 39798.0 1.44
BXD34/TyJ m 21183.0 0.0   1   0.0 0.0 21183.0, 21183.0 0.04
BXD36/TyJ m 47181.0 0.0   1   0.0 0.0 47181.0, 47181.0 2.0
BXD38/TyJ m 89346.0 0.0   1   0.0 0.0 89346.0, 89346.0 5.18
BXD39/TyJ m 6543.0 0.0   1   0.0 0.0 6543.0, 6543.0 -1.07
BXD40/TyJ m 28270.0 0.0   1   0.0 0.0 28270.0, 28270.0 0.57
BXD42/TyJ m 23415.0 0.0   1   0.0 0.0 23415.0, 23415.0 0.2
BXD5/TyJ m 17297.0 0.0   1   0.0 0.0 17297.0, 17297.0 -0.26
BXD6/TyJ m 25595.0 0.0   1   0.0 0.0 25595.0, 25595.0 0.37
BXD8/TyJ m 14227.0 0.0   1   0.0 0.0 14227.0, 14227.0 -0.49
BXD9/TyJ m 39930.0 0.0   1   0.0 0.0 39930.0, 39930.0 1.45
BXH10/TyJ m 35162.0 0.0   1   0.0 0.0 35162.0, 35162.0 1.09
BXH20/KccJ m 8154.0 0.0   1   0.0 0.0 8154.0, 8154.0 -0.95
BXH22/KccJ m 9800.0 0.0   1   0.0 0.0 9800.0, 9800.0 -0.82
BXH2/TyJ m 16366.0 0.0   1   0.0 0.0 16366.0, 16366.0 -0.33
BXH4/TyJ m 11527.0 2093.0   2   1480.0 0.182 10047.0, 13006.0 -0.69
BXH6/TyJ m 20158.0 0.0   1   0.0 0.0 20158.0, 20158.0 -0.04
BXH7/TyJ m 20336.0 0.0   1   0.0 0.0 20336.0, 20336.0 -0.03
BXH8/TyJ m 10360.0 0.0   1   0.0 0.0 10360.0, 10360.0 -0.78
BXH9/TyJ m 11411.0 0.0   1   0.0 0.0 11411.0, 11411.0 -0.7
C3H/HeJ m 20835.0 5489.0   2   3881.0 0.263 16954.0, 24716.0 0.01
C57BL/6J m 15955.0 1673.0   5 748.0 0.105 13491.0, 17754.0 -0.36
C57L/J m 26562.0 0.0   1   0.0 0.0 26562.0, 26562.0 0.44
C58/J m 35044.0 0.0   1   0.0 0.0 35044.0, 35044.0 1.08
CAST/EiJ m 21975.0 0.0   1   0.0 0.0 21975.0, 21975.0 0.1
CBA/J m 18282.0 0.0   1   0.0 0.0 18282.0, 18282.0 -0.18
CE/J m 14453.0 0.0   1   0.0 0.0 14453.0, 14453.0 -0.47
CXB11/HiAJ m 15963.0 7153.0   2   5058.0 0.448 10905.0, 21020.0 -0.36
CXB12/HiAJ m 4292.0 0.0   1   0.0 0.0 4292.0, 4292.0 -1.24
CXB13/HiAJ m 29772.0 16329.0   2   11546.0 0.548 18225.0, 41318.0 0.68
CXB1/ByJ m 10780.0 3503.0   3 2023.0 0.325 6794.0, 13369.0 -0.75
CXB2/ByJ m 10332.0 4436.0   3 2561.0 0.429 7601.0, 15450.0 -0.78
CXB3/ByJ m 8404.0 3656.0   2   2585.0 0.435 5819.0, 10990.0 -0.93
CXB4/ByJ m 9088.0 0.0   1   0.0 0.0 9088.0, 9088.0 -0.88
CXB6/ByJ m 16043.0 4498.0   3 2597.0 0.28 11095.0, 19887.0 -0.35
CXB7/ByJ m 5421.0 2341.0   2   1655.0 0.432 3765.0, 7076.0 -1.15
CXB8/HiAJ m 7007.0 2694.0   3 1555.0 0.384 3905.0, 8760.0 -1.03
CXB9/HiAJ m 5882.0 1102.0   3 637.0 0.187 4862.0, 7052.0 -1.12
DBA/2J m 26808.0 4754.0   4 2377.0 0.177 22406.0, 33478.0 0.46
FVB/NJ m 28177.0 0.0   1   0.0 0.0 28177.0, 28177.0 0.56
I/LnJ m 47399.0 0.0   1   0.0 0.0 47399.0, 47399.0 2.01
KK/HlJ m 19726.0 0.0   1   0.0 0.0 19726.0, 19726.0 -0.07
LG/J m 44771.0 0.0   1   0.0 0.0 44771.0, 44771.0 1.82
LP/J m 31467.0 0.0   1   0.0 0.0 31467.0, 31467.0 0.81
MA/MyJ m 4418.0 0.0   1   0.0 0.0 4418.0, 4418.0 -1.23
NOD/ShiLtJ m 9728.0 0.0   1   0.0 0.0 9728.0, 9728.0 -0.83
NON/ShiLtJ m 37349.0 0.0   1   0.0 0.0 37349.0, 37349.0 1.26
NZW/LacJ m 18793.0 0.0   1   0.0 0.0 18793.0, 18793.0 -0.14
PL/J m 18398.0 0.0   1   0.0 0.0 18398.0, 18398.0 -0.17
RIIIS/J m 14584.0 0.0   1   0.0 0.0 14584.0, 14584.0 -0.46
SEA/GnJ m 22972.0 0.0   1   0.0 0.0 22972.0, 22972.0 0.17
SJL/J m 28553.0 0.0   1   0.0 0.0 28553.0, 28553.0 0.59
SM/J m 56992.0 0.0   1   0.0 0.0 56992.0, 56992.0 2.74
SWR/J m 42470.0 0.0   1   0.0 0.0 42470.0, 42470.0 1.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 9052.65 3906.4779 17019.9641 1085.3359
AXB19b/PgnJ m 19009.35 3906.4779 26976.6641 11042.0359
AXB24/PgnJ m 6635.0 3906.4779 14602.3141 0.0
BALB/cJ m 13055.6333 3189.6258 19560.9181 6550.3486
BXA16/PgnJ m 20646.6 3906.4779 28613.9141 12679.2859
BXD19/TyJ m 35313.1 3906.4779 43280.4141 27345.7859
BXD28/TyJ m 10805.6 3906.4779 18772.9141 2838.2859
BXH4/TyJ m 11526.65 3906.4779 19493.9641 3559.3359
C3H/HeJ m 20835.3 3906.4779 28802.6141 12867.9859
C57BL/6J m 15954.62 2470.6735 20993.5919 10915.6481
CXB11/HiAJ m 15962.65 3906.4779 23929.9641 7995.3359
CXB13/HiAJ m 29771.5 3906.4779 37738.8141 21804.1859
CXB1/ByJ m 10779.8333 3189.6258 17285.1181 4274.5486
CXB2/ByJ m 10332.4667 3189.6258 16837.7514 3827.1819
CXB3/ByJ m 8404.05 3906.4779 16371.3641 436.7359
CXB6/ByJ m 16043.1333 3189.6258 22548.4181 9537.8486
CXB7/ByJ m 5420.75 3906.4779 13388.0641 0.0
CXB8/HiAJ m 7007.1667 3189.6258 13512.4514 501.8819
CXB9/HiAJ m 5881.8 3189.6258 12387.0847 0.0
DBA/2J m 26808.175 2762.297 32441.9168 21174.4332




  GWAS USING LINEAR MIXED MODELS