Project measure / variable:   Brugnara1   magnesium

ID, description, units MPD:47403   magnesium   RBC magnesium cation content (mmol/kg hemoglobin)   [mmol/kg]  
Data set, strains Brugnara1   inbred   10 strains     sex: both     age: 8wks
Procedure ion transport assessment
Ontology mappings

  STRAIN COMPARISON PLOT
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Brugnara1 - RBC magnesium cation content (mmol/kg hemoglobin)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means7.29   mmol/kg 7.77   mmol/kg
Median of the strain means7.27   mmol/kg 7.64   mmol/kg
SD of the strain means± 0.857 ± 1.19
Coefficient of variation (CV)0.118 0.153
Min–max range of strain means5.78   –   8.90   mmol/kg 5.77   –   9.23   mmol/kg
Mean sample size per strain30.0   mice 26.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 37.9208 37.9208 19.4505 < 0.0001
strain 9 474.4411 52.7157 27.0392 < 0.0001
sex:strain 9 66.1916 7.3546 3.7724 0.0001
Residuals 536 1044.9876 1.9496


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.59 1.89   33 0.328 0.286 0.19, 8.53 -0.82
129S1/SvImJ m 7.34 1.28   24 0.262 0.175 4.32, 9.84 -0.36
A/J f 5.78 1.63   31 0.293 0.282 3.07, 8.88 -1.76
A/J m 5.77 1.72   22 0.367 0.298 3.21, 8.93 -1.68
BALB/cJ f 6.6 1.3   26 0.255 0.197 4.28, 9.51 -0.81
BALB/cJ m 6.6 0.772   30 0.141 0.117 4.53, 7.96 -0.98
C3H/HeJ f 7.18 1.23   20 0.276 0.172 4.02, 8.13 -0.13
C3H/HeJ m 7.95 0.994   24 0.203 0.125 5.6, 9.37 0.15
C57BL/6J f 7.91 1.59   33 0.277 0.201 5.24, 10.9 0.72
C57BL/6J m 9.23 1.7   31 0.305 0.184 6.21, 13.0 1.22
C57BLKS/J f 8.9 1.39   32 0.246 0.156 5.24, 11.5 1.88
C57BLKS/J m 8.99 1.32   34 0.226 0.147 5.67, 11.1 1.02
CBA/J f 7.6 0.791   32 0.14 0.104 5.54, 8.7 0.36
CBA/J m 7.07 1.36   34 0.233 0.192 4.51, 9.01 -0.59
DBA/2J f 7.23 1.75   30 0.319 0.242 4.47, 10.1 -0.07
DBA/2J m 7.0 1.32   18 0.31 0.188 3.95, 8.5 -0.65
NZW/LacJ f 7.81 0.964   28 0.182 0.123 5.81, 8.7 0.61
NZW/LacJ m 8.84 0.948   19 0.218 0.107 7.12, 10.4 0.89
SM/J f 7.3 1.81   28 0.343 0.249 4.89, 11.2 0.01
SM/J m 8.94 1.01   27 0.194 0.113 7.26, 10.6 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.5948 0.2431 7.0723 6.1174
129S1/SvImJ m 7.3417 0.285 7.9015 6.7818
A/J f 5.7832 0.2508 6.2759 5.2906
A/J m 5.7732 0.2977 6.358 5.1884
BALB/cJ f 6.6042 0.2738 7.1421 6.0663
BALB/cJ m 6.605 0.2549 7.1058 6.1042
C3H/HeJ f 7.181 0.3122 7.7943 6.5677
C3H/HeJ m 7.9458 0.285 8.5057 7.386
C57BL/6J f 7.9124 0.2431 8.3899 7.435
C57BL/6J m 9.2277 0.2508 9.7204 8.7351
C57BLKS/J f 8.9044 0.2468 9.3892 8.4195
C57BLKS/J m 8.9888 0.2395 9.4592 8.5184
CBA/J f 7.5963 0.2468 8.0811 7.1114
CBA/J m 7.0709 0.2395 7.5413 6.6005
DBA/2J f 7.2303 0.2549 7.7311 6.7296
DBA/2J m 7.005 0.3291 7.6515 6.3585
NZW/LacJ f 7.8129 0.2639 8.3312 7.2945
NZW/LacJ m 8.8437 0.3203 9.4729 8.2144
SM/J f 7.2961 0.2639 7.8144 6.7777
SM/J m 8.94 0.2687 9.4679 8.4121


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.9683 0.1873 7.3362 6.6003
A/J both 5.7782 0.1946 6.1605 5.3959
BALB/cJ both 6.6046 0.1871 6.9721 6.2371
C3H/HeJ both 7.5634 0.2114 7.9786 7.1482
C57BL/6J both 8.5701 0.1746 8.9131 8.2271
C57BLKS/J both 8.9466 0.1719 9.2844 8.6088
CBA/J both 7.3336 0.1719 7.6713 6.9958
DBA/2J both 7.1177 0.2081 7.5265 6.7088
NZW/LacJ both 8.3283 0.2075 8.7359 7.9206
SM/J both 8.118 0.1883 8.4879 7.7481




  GWAS USING LINEAR MIXED MODELS