Project measure / variable:   Brugnara1   sodium

ID, description, units MPD:47401   sodium   RBC sodium cation content (mmol/kg hemoglobin)   [mmol/kg]  
Data set, strains Brugnara1   inbred   10 strains     sex: both     age: 8wks
Procedure ion transport assessment
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  STRAIN COMPARISON PLOT
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Brugnara1 - RBC sodium cation content (mmol/kg hemoglobin)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means20.1   mmol/kg 21.2   mmol/kg
Median of the strain means18.4   mmol/kg 18.1   mmol/kg
SD of the strain means± 4.87 ± 7.87
Coefficient of variation (CV)0.242 0.371
Min–max range of strain means16.7   –   32.3   mmol/kg 16.1   –   39.1   mmol/kg
Mean sample size per strain30.8   mice 31.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 197.633 197.633 26.7483 < 0.0001
strain 9 21433.8521 2381.5391 322.3259 < 0.0001
sex:strain 9 1398.4882 155.3876 21.0307 < 0.0001
Residuals 595 4396.2207 7.3886


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 16.7 1.8   33 0.314 0.108 14.2, 21.6 -0.71
129S1/SvImJ m 16.6 2.22   34 0.381 0.134 10.4, 21.0 -0.59
A/J f 18.2 1.4   33 0.245 0.0772 15.8, 21.3 -0.4
A/J m 19.4 2.77   29 0.515 0.143 15.8, 25.9 -0.23
BALB/cJ f 18.6 1.56   26 0.307 0.0843 16.1, 23.2 -0.32
BALB/cJ m 18.7 1.93   30 0.352 0.103 14.9, 23.2 -0.32
C3H/HeJ f 17.5 1.15   30 0.21 0.0657 15.2, 20.4 -0.54
C3H/HeJ m 16.1 2.09   30 0.381 0.13 10.6, 21.4 -0.65
C57BL/6J f 16.9 2.86   35 0.483 0.169 10.3, 23.2 -0.67
C57BL/6J m 17.0 2.48   32 0.438 0.145 12.0, 22.6 -0.54
C57BLKS/J f 20.1 1.48   32 0.261 0.0735 17.5, 24.6 -0.01
C57BLKS/J m 19.6 2.81   39 0.45 0.144 16.0, 33.7 -0.21
CBA/J f 18.8 1.87   31 0.335 0.0991 15.4, 22.4 -0.28
CBA/J m 17.5 1.86   34 0.319 0.106 12.5, 20.9 -0.47
DBA/2J f 17.6 1.43   30 0.261 0.0815 15.5, 21.0 -0.52
DBA/2J m 16.1 1.68   22 0.358 0.104 13.0, 19.2 -0.65
NZW/LacJ f 32.3 4.52   31 0.813 0.14 23.2, 38.8 2.5
NZW/LacJ m 39.1 4.17   28 0.789 0.107 31.5, 45.2 2.27
SM/J f 24.8 4.84   24 0.988 0.196 17.5, 35.3 0.96
SM/J m 32.2 4.82   32 0.852 0.15 22.4, 40.5 1.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 16.6791 0.4732 17.6084 15.7498
129S1/SvImJ m 16.5671 0.4662 17.4826 15.6515
A/J f 18.1897 0.4732 19.119 17.2604
A/J m 19.4145 0.5048 20.4058 18.4232
BALB/cJ f 18.5565 0.5331 19.6035 17.5096
BALB/cJ m 18.6843 0.4963 19.659 17.7097
C3H/HeJ f 17.4893 0.4963 18.464 16.5147
C3H/HeJ m 16.0703 0.4963 17.045 15.0957
C57BL/6J f 16.9069 0.4595 17.8092 16.0045
C57BL/6J m 17.0459 0.4805 17.9896 16.1022
C57BLKS/J f 20.1247 0.4805 21.0684 19.181
C57BLKS/J m 19.57 0.4353 20.4248 18.7152
CBA/J f 18.8203 0.4882 19.7791 17.8615
CBA/J m 17.475 0.4662 18.3905 16.5595
DBA/2J f 17.5623 0.4963 18.537 16.5877
DBA/2J m 16.1245 0.5795 17.2627 14.9864
NZW/LacJ f 32.3081 0.4882 33.2669 31.3493
NZW/LacJ m 39.1004 0.5137 40.1092 38.0915
SM/J f 24.7546 0.5549 25.8443 23.6649
SM/J m 32.1763 0.4805 33.12 31.2325


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 16.6231 0.3321 17.2753 15.9708
A/J both 18.8021 0.3459 19.4815 18.1227
BALB/cJ both 18.6204 0.3642 19.3356 17.9052
C3H/HeJ both 16.7798 0.3509 17.469 16.0906
C57BL/6J both 16.9764 0.3324 17.6292 16.3235
C57BLKS/J both 19.8473 0.3242 20.484 19.2107
CBA/J both 18.1477 0.3375 18.8105 17.4848
DBA/2J both 16.8434 0.3815 17.5927 16.0942
NZW/LacJ both 35.7042 0.3543 36.4001 35.0083
SM/J both 28.4654 0.367 29.1862 27.7446




  GWAS USING LINEAR MIXED MODELS