Project measure / variable:   Rusyn5   ALT_hf

ID, description, units MPD:43001   ALT_hf   serum alanine transaminase (ALT)   [IU/L]  high-fat only  
high-fat diet and ethanol study
Data set, strains Rusyn5   inbred   14 strains     sex: m     age: 8-14wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn5 - serum alanine transaminase (ALT) high-fat only



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested14 strains
Mean of the strain means25.1   IU/L
Median of the strain means21.4   IU/L
SD of the strain means± 12.3
Coefficient of variation (CV)0.492
Min–max range of strain means10.5   –   54.0   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 5927.9625 455.9971 1.7618 0.102
Residuals 28 7247.1354 258.8263


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 10.5 3.39   3 1.96 0.324 7.82, 14.3 -1.18
AKR/J m 25.2 7.92   3 4.57 0.314 20.5, 34.4 0.01
BALB/cByJ m 15.6 1.99   3 1.15 0.127 13.6, 17.5 -0.77
BALB/cJ m 21.4 6.88   3 3.97 0.321 15.8, 29.1 -0.3
BTBR T+ Itpr3tf/J m 17.5 2.29   3 1.32 0.13 15.6, 20.0 -0.61
C3H/HeJ m 16.5 2.41   3 1.39 0.146 14.7, 19.3 -0.7
C57BL/10J m 15.6 5.87   3 3.39 0.378 9.48, 21.2 -0.77
DBA/2J m 19.5 4.94   3 2.85 0.253 16.2, 25.2 -0.45
FVB/NJ m 26.7 17.1   3 9.9 0.642 16.4, 46.5 0.13
KK/HlJ m 54.0 29.6   3 17.1 0.549 21.7, 80.0 2.34
MOLF/EiJ m 21.4 3.25   3 1.88 0.152 18.0, 24.5 -0.3
NZW/LacJ m 24.0 6.4   3 3.69 0.267 17.4, 30.1 -0.09
PWD/PhJ m 39.3 3.63   3 2.1 0.0924 35.9, 43.1 1.15
WSB/EiJ m 43.9 46.8   3 27.0 1.07 16.5, 97.9 1.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 10.48 9.2885 29.5065 0.0
AKR/J m 25.2133 9.2885 44.2399 6.1868
BALB/cByJ m 15.63 9.2885 34.6565 0.0
BALB/cJ m 21.4433 9.2885 40.4699 2.4168
BTBR T+ Itpr3tf/J m 17.5467 9.2885 36.5732 0.0
C3H/HeJ m 16.5333 9.2885 35.5599 0.0
C57BL/10J m 15.55 9.2885 34.5765 0.0
DBA/2J m 19.52 9.2885 38.5465 0.4935
FVB/NJ m 26.6967 9.2885 45.7232 7.6701
KK/HlJ m 53.9867 9.2885 73.0132 34.9601
MOLF/EiJ m 21.37 9.2885 40.3965 2.3435
NZW/LacJ m 23.9633 9.2885 42.9899 4.9368
PWD/PhJ m 39.3267 9.2885 58.3532 20.3001
WSB/EiJ m 43.8567 9.2885 62.8832 24.8301




  GWAS USING LINEAR MIXED MODELS