Project measure / variable:   Gould1   brain_lithium300

ID, description, units MPD:37409   brain_lithium300   brain lithium concentration   [mmol/L]  dose 300 mg/kg  
lithium study
Data set, strains Gould1   inbred   11 strains     sex: m     age: 7-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Gould1 - brain lithium concentration dose 300 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested11 strains
Mean of the strain means1.51   mmol/L
Median of the strain means1.38   mmol/L
SD of the strain means± 0.271
Coefficient of variation (CV)0.179
Min–max range of strain means1.09   –   1.88   mmol/L
Mean sample size per strain7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 10 5.3602 0.536 10.0499 < 0.0001
Residuals 72 3.8402 0.0533


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 1.36 0.147   8 0.0518 0.108 1.12, 1.6 -0.55
A/J m 1.84 0.143   8 0.0507 0.0779 1.6, 2.0 1.22
BALB/cJ m 1.7 0.259   8 0.0916 0.153 1.36, 2.12 0.7
C3H/HeNHsd m 1.88 0.283   8 0.1 0.15 1.64, 2.36 1.37
C57BL/6J m 1.38 0.103   7 0.0389 0.0747 1.24, 1.56 -0.48
CBA/J m 1.38 0.128   8 0.0453 0.0932 1.08, 1.48 -0.48
Crl:CD-1(ICR) m 1.27 0.317   6 0.13 0.249 0.88, 1.68 -0.89
DBA/2J m 1.56 0.173   8 0.0611 0.111 1.32, 1.88 0.18
FVB/NJ m 1.09 0.0787   6 0.0321 0.0719 0.96, 1.16 -1.55
Hsd:NIHS m 1.3 0.394   8 0.139 0.304 0.8, 1.96 -0.77
NTac:NIHBS m 1.85 0.268   8 0.0948 0.145 1.44, 2.36 1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 1.36 0.0817 1.5228 1.1972
A/J m 1.84 0.0817 2.0028 1.6772
BALB/cJ m 1.695 0.0817 1.8578 1.5322
C3H/HeNHsd m 1.885 0.0817 2.0478 1.7222
C57BL/6J m 1.3771 0.0873 1.5512 1.2031
CBA/J m 1.375 0.0817 1.5378 1.2122
Crl:CD-1(ICR) m 1.2733 0.0943 1.4613 1.0854
DBA/2J m 1.555 0.0817 1.7178 1.3922
FVB/NJ m 1.0933 0.0943 1.2813 0.9054
Hsd:NIHS m 1.295 0.0817 1.4578 1.1322
NTac:NIHBS m 1.845 0.0817 2.0078 1.6822




  GWAS USING LINEAR MIXED MODELS