Project measure / variable:   Vulpe1   2Fe_transferrin

ID, description, units MPD:36804   2Fe_transferrin   diferric transferrin (serum), percentage of total transferrin   [%]  
Data set, strains Vulpe1   inbred   18 strains     sex: both     age: 8wks
Procedure transferrin quantification
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  STRAIN COMPARISON PLOT
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Vulpe1 - diferric transferrin (serum), percentage of total transferrin



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested18 strains17 strains
Mean of the strain means35.4   % 35.8   %
Median of the strain means38.3   % 36.1   %
SD of the strain means± 14.0 ± 13.5
Coefficient of variation (CV)0.396 0.377
Min–max range of strain means9.72   –   52.4   % 10.7   –   57.0   %
Mean sample size per strain6.5   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 53.2475 53.2475 0.3023 0.5831
strain 16 34309.1716 2144.3232 12.1726 < 0.0001
sex:strain 16 2997.1871 187.3242 1.0634 0.393
Residuals 189 33294.1088 176.1593


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 43.4 17.8   6 7.25 0.409 24.2, 68.1 0.57
129S1/SvImJ m 46.2 22.6   6 9.21 0.488 3.86, 66.7 0.77
A/HeJ f 38.7 14.6   6 5.96 0.377 21.1, 55.9 0.24
A/HeJ m 35.4 10.9   6 4.44 0.307 24.1, 51.3 -0.03
A/J f 52.4 4.55   6 1.86 0.0868 47.3, 59.4 1.22
A/J m 48.4 24.1   6 9.84 0.498 24.1, 78.4 0.93
AKR/J f 47.0 5.59   6 2.28 0.119 39.1, 53.3 0.83
AKR/J m 53.0 8.01   6 3.27 0.151 42.9, 64.3 1.27
B10.D2-Hc0 f 30.7 11.6   6 4.73 0.377 13.1, 40.4 -0.33
B10.D2-Hc0 m 23.1 16.9   6 6.89 0.732 11.2, 55.4 -0.94
BALB/cByJ f 45.4 16.6   6 6.78 0.366 16.3, 59.5 0.72
BALB/cByJ m 46.9 10.3   6 4.21 0.22 32.6, 58.2 0.82
BALB/cJ f 33.9 5.59   6 2.28 0.165 27.3, 41.7 -0.1
BALB/cJ m 33.7 9.35   5 4.18 0.278 23.3, 46.5 -0.16
C3H/HeJ f 18.9 7.73   5 3.46 0.41 7.46, 27.3 -1.18
C3H/HeJ m 20.6 15.1   6 6.14 0.729 8.32, 49.3 -1.13
C57BL/6J f 16.4 12.6   10 4.0 0.771 2.62, 38.4 -1.35
C57BL/6J m 20.8 18.1   6 7.39 0.87 6.01, 54.0 -1.11
CAST/EiJ f 48.6 14.2   11 4.27 0.291 20.5, 65.8 0.95
CAST/EiJ m 43.3 19.4   7 7.33 0.447 14.0, 66.4 0.55
DBA/2J f 45.1 11.0   12 3.17 0.243 25.2, 58.8 0.7
DBA/2J m 37.1 17.0   12 4.89 0.456 15.7, 62.0 0.1
LG/J f 47.8 14.3   6 5.83 0.299 32.4, 68.5 0.89
LG/J m 48.8 11.9   6 4.85 0.243 36.4, 67.6 0.96
LP/J f 37.9 10.1   6 4.12 0.266 25.1, 55.4 0.18
LP/J m 26.4 5.3   6 2.16 0.201 19.9, 33.2 -0.7
MRL/MpJ f 51.7 6.36   6 2.59 0.123 42.8, 57.1 1.17
MRL/MpJ m 57.0 8.9   6 3.63 0.156 49.1, 70.4 1.57
NZB/BlNJ f 29.0 7.01   6 2.86 0.242 22.5, 41.8 -0.45
NZB/BlNJ m 21.4 16.2   10 5.12 0.755 8.78, 59.0 -1.07
NZW/LacJ f 30.0 16.2   6 6.62 0.541 8.45, 45.2 -0.38
SM/J f 9.9 4.12   3 2.38 0.416 5.21, 12.9 -1.82
SM/J m 36.1 9.26   6 3.78 0.256 28.1, 53.7 0.02
SPRET/EiJ f 9.72 3.03   6 1.24 0.311 4.91, 12.5 -1.83
SPRET/EiJ m 10.7 8.87   4 4.44 0.831 4.99, 23.9 -1.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 43.4117 5.4185 54.1001 32.7232
129S1/SvImJ m 46.2417 5.4185 56.9301 35.5532
A/HeJ f 38.715 5.4185 49.4035 28.0265
A/HeJ m 35.4333 5.4185 46.1218 24.7449
A/J f 52.3867 5.4185 63.0751 41.6982
A/J m 48.39 5.4185 59.0785 37.7015
AKR/J f 46.9767 5.4185 57.6651 36.2882
AKR/J m 52.9933 5.4185 63.6818 42.3049
B10.D2-Hc0 f 30.7067 5.4185 41.3951 20.0182
B10.D2-Hc0 m 23.0533 5.4185 33.7418 12.3649
BALB/cByJ f 45.3533 5.4185 56.0418 34.6649
BALB/cByJ m 46.8817 5.4185 57.5701 36.1932
BALB/cJ f 33.935 5.4185 44.6235 23.2465
BALB/cJ m 33.664 5.9356 45.3726 21.9554
C3H/HeJ f 18.882 5.9356 30.5906 7.1734
C3H/HeJ m 20.6433 5.4185 31.3318 9.9549
C57BL/6J f 16.406 4.1971 24.6852 8.1268
C57BL/6J m 20.8 5.4185 31.4885 10.1115
CAST/EiJ f 48.6136 4.0018 56.5076 40.7197
CAST/EiJ m 43.3457 5.0165 53.2413 33.4501
DBA/2J f 45.11 3.8314 52.6679 37.5521
DBA/2J m 37.1442 3.8314 44.702 29.5863
LG/J f 47.7783 5.4185 58.4668 37.0899
LG/J m 48.8483 5.4185 59.5368 38.1599
LP/J f 37.925 5.4185 48.6135 27.2365
LP/J m 26.4383 5.4185 37.1268 15.7499
MRL/MpJ f 51.7433 5.4185 62.4318 41.0549
MRL/MpJ m 57.02 5.4185 67.7085 46.3315
NZB/BlNJ f 28.97 5.4185 39.6585 18.2815
NZB/BlNJ m 21.444 4.1971 29.7232 13.1648
SM/J f 9.9033 7.6629 25.0191 0.0
SM/J m 36.1133 5.4185 46.8018 25.4249
SPRET/EiJ f 9.72 5.4185 20.4085 0.0
SPRET/EiJ m 10.6775 6.6363 23.7681 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 44.8267 3.8314 52.3845 37.2688
A/HeJ both 37.0742 3.8314 44.632 29.5163
A/J both 50.3883 3.8314 57.9462 42.8305
AKR/J both 49.985 3.8314 57.5429 42.4271
B10.D2-Hc0 both 26.88 3.8314 34.4379 19.3221
BALB/cByJ both 46.1175 3.8314 53.6754 38.5596
BALB/cJ both 33.7995 4.0184 41.7263 25.8727
C3H/HeJ both 19.7627 4.0184 27.6894 11.8359
C57BL/6J both 18.603 3.4269 25.363 11.843
CAST/EiJ both 45.9797 3.2086 52.3089 39.6504
DBA/2J both 41.1271 2.7092 46.4713 35.7829
LG/J both 48.3133 3.8314 55.8712 40.7555
LP/J both 32.1817 3.8314 39.7395 24.6238
MRL/MpJ both 54.3817 3.8314 61.9395 46.8238
NZB/BlNJ both 25.207 3.4269 31.967 18.447
SM/J both 23.0083 4.6925 32.2648 13.7519
SPRET/EiJ both 10.1987 4.2837 18.6487 1.7488




  GWAS USING LINEAR MIXED MODELS