Project measure / variable:   Berndt2   breath_freq_mch20

ID, description, units MPD:35111   breath_freq_mch20   breath frequency   [n/min]  20 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - breath frequency 20 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means234   n/min 231   n/min
Median of the strain means230   n/min 232   n/min
SD of the strain means± 45.2 ± 46.3
Coefficient of variation (CV)0.193 0.200
Min–max range of strain means157   –   315   n/min 135   –   319   n/min
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 316.9095 316.9095 0.1917 0.6617
strain 28 879958.2718 31427.0811 19.0109 < 0.0001
sex:strain 28 85907.5071 3068.1253 1.856 0.0057
Residuals 412 681082.4288 1653.1127


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 218.0 41.5   8 14.7 0.191 174.0, 281.0 -0.35
129S1/SvImJ m 227.0 44.2   8 15.6 0.195 146.0, 293.0 -0.08
A/J f 159.0 51.1   8 18.1 0.323 97.1, 228.0 -1.66
A/J m 135.0 24.5   8 8.67 0.182 105.0, 181.0 -2.07
AKR/J f 230.0 58.1   8 20.5 0.252 159.0, 360.0 -0.09
AKR/J m 247.0 25.1   8 8.89 0.102 210.0, 278.0 0.35
BALB/cByJ f 266.0 48.0   8 17.0 0.181 193.0, 356.0 0.71
BALB/cByJ m 304.0 41.8   8 14.8 0.137 225.0, 350.0 1.58
BALB/cJ f 306.0 32.0   10 10.1 0.105 240.0, 337.0 1.59
BALB/cJ m 319.0 31.8   10 10.1 0.0999 258.0, 376.0 1.9
BTBR T+ Itpr3tf/J f 180.0 56.2   8 19.9 0.312 137.0, 313.0 -1.19
BTBR T+ Itpr3tf/J m 205.0 44.5   8 15.7 0.217 116.0, 254.0 -0.56
BUB/BnJ f 209.0 69.6   7 26.3 0.334 90.8, 321.0 -0.55
BUB/BnJ m 162.0 42.2   8 14.9 0.261 101.0, 241.0 -1.49
C3H/HeJ f 192.0 39.4   8 13.9 0.205 142.0, 253.0 -0.93
C3H/HeJ m 190.0 50.4   8 17.8 0.265 110.0, 290.0 -0.88
C57BL/10J f 298.0 35.0   8 12.4 0.118 233.0, 338.0 1.42
C57BL/10J m 254.0 44.6   7 16.9 0.176 193.0, 314.0 0.5
C57BL/6J f 277.0 31.2   7 11.8 0.113 238.0, 317.0 0.95
C57BL/6J m 288.0 29.2   13 8.11 0.101 226.0, 345.0 1.23
C57BLKS/J f 278.0 37.5   11 11.3 0.135 220.0, 340.0 0.97
C57BLKS/J m 250.0 45.8   8 16.2 0.183 187.0, 313.0 0.41
C57BR/cdJ f 315.0 41.0   6 16.7 0.13 257.0, 373.0 1.79
C57BR/cdJ m 277.0 36.5   8 12.9 0.132 237.0, 347.0 1.0
C57L/J f 286.0 26.8   8 9.48 0.0938 238.0, 316.0 1.15
C57L/J m 262.0 21.5   8 7.59 0.0819 222.0, 294.0 0.67
CBA/J f 260.0 28.4   8 10.0 0.109 211.0, 296.0 0.58
CBA/J m 270.0 21.1   8 7.46 0.0783 233.0, 292.0 0.85
CE/J f 243.0 44.5   8 15.7 0.184 187.0, 305.0 0.2
CE/J m 215.0 43.3   9 14.4 0.201 161.0, 298.0 -0.34
DBA/1J f 219.0 40.5   10 12.8 0.185 183.0, 304.0 -0.33
DBA/1J m 167.0 26.6   8 9.41 0.159 128.0, 213.0 -1.38
DBA/2J f 244.0 50.5   8 17.9 0.207 201.0, 339.0 0.22
DBA/2J m 232.0 28.8   10 9.1 0.124 192.0, 296.0 0.02
FVB/NJ f 228.0 37.3   8 13.2 0.163 163.0, 271.0 -0.13
FVB/NJ m 280.0 26.9   7 10.2 0.0962 250.0, 326.0 1.06
I/LnJ f 211.0 67.2   7 25.4 0.319 101.0, 285.0 -0.51
I/LnJ m 207.0 75.2   5 33.6 0.363 102.0, 265.0 -0.52
KK/HlJ f 239.0 33.0   8 11.7 0.138 191.0, 282.0 0.11
KK/HlJ m 208.0 33.5   6 13.7 0.161 161.0, 262.0 -0.49
LP/J f 198.0 48.6   8 17.2 0.246 134.0, 275.0 -0.8
LP/J m 246.0 49.0   8 17.3 0.199 196.0, 342.0 0.33
NOD/ShiLtJ f 281.0 37.8   8 13.4 0.135 240.0, 353.0 1.04
NOD/ShiLtJ m 296.0 46.9   8 16.6 0.158 236.0, 362.0 1.41
NON/ShiLtJ f 157.0 39.6   8 14.0 0.251 111.0, 219.0 -1.7
NON/ShiLtJ m 176.0 29.1   8 10.3 0.166 131.0, 225.0 -1.19
NZW/LacJ f 202.0 25.3   8 8.94 0.125 169.0, 239.0 -0.71
NZW/LacJ m 216.0 43.9   8 15.5 0.204 148.0, 282.0 -0.32
PL/J f 164.0 36.9   8 13.1 0.225 121.0, 227.0 -1.55
PL/J m 174.0 42.1   8 14.9 0.242 144.0, 274.0 -1.23
RIIIS/J f 258.0 41.2   8 14.6 0.16 220.0, 345.0 0.53
RIIIS/J m 236.0 30.1   8 10.6 0.128 194.0, 276.0 0.11
SJL/J f 206.0 41.9   8 14.8 0.203 160.0, 286.0 -0.62
SJL/J m 218.0 30.2   8 10.7 0.139 168.0, 255.0 -0.28
SM/J f 277.0 24.5   8 8.67 0.0885 247.0, 323.0 0.95
SM/J m 250.0 56.5   8 20.0 0.225 162.0, 310.0 0.41
SWR/J f 184.0 48.4   8 17.1 0.263 137.0, 255.0 -1.1
SWR/J m 184.0 26.2   9 8.73 0.142 139.0, 228.0 -1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 217.5 14.3749 245.7574 189.2426
129S1/SvImJ m 226.875 14.3749 255.1324 198.6176
A/J f 158.5125 14.3749 186.7699 130.2551
A/J m 134.875 14.3749 163.1324 106.6176
AKR/J f 230.5 14.3749 258.7574 202.2426
AKR/J m 247.0 14.3749 275.2574 218.7426
BALB/cByJ f 265.875 14.3749 294.1324 237.6176
BALB/cByJ m 303.75 14.3749 332.0074 275.4926
BALB/cJ f 306.2 12.8573 331.4742 280.9258
BALB/cJ m 318.6 12.8573 343.8742 293.3258
BTBR T+ Itpr3tf/J f 180.5 14.3749 208.7574 152.2426
BTBR T+ Itpr3tf/J m 205.0 14.3749 233.2574 176.7426
BUB/BnJ f 208.6857 15.3675 238.8941 178.4773
BUB/BnJ m 161.625 14.3749 189.8824 133.3676
C3H/HeJ f 191.875 14.3749 220.1324 163.6176
C3H/HeJ m 190.25 14.3749 218.5074 161.9926
C57BL/10J f 297.75 14.3749 326.0074 269.4926
C57BL/10J m 253.7143 15.3675 283.9227 223.5059
C57BL/6J f 277.0 15.3675 307.2084 246.7916
C57BL/6J m 288.1538 11.2766 310.3208 265.9869
C57BLKS/J f 277.6364 12.259 301.7343 253.5384
C57BLKS/J m 250.0 14.3749 278.2574 221.7426
C57BR/cdJ f 315.0 16.5988 347.6288 282.3712
C57BR/cdJ m 276.875 14.3749 305.1324 248.6176
C57L/J f 285.875 14.3749 314.1324 257.6176
C57L/J m 262.375 14.3749 290.6324 234.1176
CBA/J f 260.375 14.3749 288.6324 232.1176
CBA/J m 269.5 14.3749 297.7574 241.2426
CE/J f 242.625 14.3749 270.8824 214.3676
CE/J m 214.7778 13.5528 241.4191 188.1365
DBA/1J f 219.0 12.8573 244.2742 193.7258
DBA/1J m 167.125 14.3749 195.3824 138.8676
DBA/2J f 244.5 14.3749 272.7574 216.2426
DBA/2J m 232.2 12.8573 257.4742 206.9258
FVB/NJ f 228.375 14.3749 256.6324 200.1176
FVB/NJ m 279.8571 15.3675 310.0656 249.6487
I/LnJ f 210.7143 15.3675 240.9227 180.5059
I/LnJ m 207.2 18.183 242.9431 171.4569
KK/HlJ f 238.875 14.3749 267.1324 210.6176
KK/HlJ m 208.1667 16.5988 240.7955 175.5378
LP/J f 197.625 14.3749 225.8824 169.3676
LP/J m 246.25 14.3749 274.5074 217.9926
NOD/ShiLtJ f 281.0 14.3749 309.2574 252.7426
NOD/ShiLtJ m 296.25 14.3749 324.5074 267.9926
NON/ShiLtJ f 157.375 14.3749 185.6324 129.1176
NON/ShiLtJ m 175.5 14.3749 203.7574 147.2426
NZW/LacJ f 201.875 14.3749 230.1324 173.6176
NZW/LacJ m 215.5 14.3749 243.7574 187.2426
PL/J f 164.375 14.3749 192.6324 136.1176
PL/J m 174.125 14.3749 202.3824 145.8676
RIIIS/J f 257.75 14.3749 286.0074 229.4926
RIIIS/J m 235.625 14.3749 263.8824 207.3676
SJL/J f 206.25 14.3749 234.5074 177.9926
SJL/J m 217.5 14.3749 245.7574 189.2426
SM/J f 277.125 14.3749 305.3824 248.8676
SM/J m 250.5 14.3749 278.7574 222.2426
SWR/J f 184.125 14.3749 212.3824 155.8676
SWR/J m 184.2222 13.5528 210.8635 157.5809


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 222.1875 10.1646 242.1685 202.2065
A/J both 146.6937 10.1646 166.6747 126.7128
AKR/J both 238.75 10.1646 258.731 218.769
BALB/cByJ both 284.8125 10.1646 304.7935 264.8315
BALB/cJ both 312.4 9.0915 330.2715 294.5285
BTBR T+ Itpr3tf/J both 192.75 10.1646 212.731 172.769
BUB/BnJ both 185.1554 10.5214 205.8376 164.4731
C3H/HeJ both 191.0625 10.1646 211.0435 171.0815
C57BL/10J both 275.7321 10.5214 296.4144 255.0499
C57BL/6J both 282.5769 9.5305 301.3114 263.8425
C57BLKS/J both 263.8182 9.4462 282.3869 245.2494
C57BR/cdJ both 295.9375 10.979 317.5194 274.3556
C57L/J both 274.125 10.1646 294.106 254.144
CBA/J both 264.9375 10.1646 284.9185 244.9565
CE/J both 228.7014 9.8782 248.1194 209.2834
DBA/1J both 193.0625 9.643 212.0181 174.1069
DBA/2J both 238.35 9.643 257.3056 219.3944
FVB/NJ both 254.1161 10.5214 274.7984 233.4338
I/LnJ both 208.9571 11.9036 232.3565 185.5578
KK/HlJ both 223.5208 10.979 245.1028 201.9389
LP/J both 221.9375 10.1646 241.9185 201.9565
NOD/ShiLtJ both 288.625 10.1646 308.606 268.644
NON/ShiLtJ both 166.4375 10.1646 186.4185 146.4565
NZW/LacJ both 208.6875 10.1646 228.6685 188.7065
PL/J both 169.25 10.1646 189.231 149.269
RIIIS/J both 246.6875 10.1646 266.6685 226.7065
SJL/J both 211.875 10.1646 231.856 191.894
SM/J both 263.8125 10.1646 283.7935 243.8315
SWR/J both 184.1736 9.8782 203.5916 164.7556




  GWAS USING LINEAR MIXED MODELS