Project measure / variable:   Shockley1   CA

ID, description, units MPD:33403   CA   calcium (serum Ca)   [mg/dL]  control diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Shockley1 - calcium (serum Ca) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means3.06   mg/dL 3.16   mg/dL
Median of the strain means2.97   mg/dL 3.49   mg/dL
SD of the strain means± 0.564 ± 0.514
Coefficient of variation (CV)0.185 0.163
Min–max range of strain means2.32   –   3.84   mg/dL 2.42   –   3.76   mg/dL
Mean sample size per strain4.9   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4227 0.4227 2.3267 0.1313
strain 9 20.1374 2.2375 12.3167 < 0.0001
sex:strain 9 5.4719 0.608 3.3468 0.0017
Residuals 77 13.988 0.1817


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.38 0.342   5 0.153 0.101 2.9, 3.8 0.57
129S1/SvImJ m 3.76 0.422   5 0.189 0.112 3.5, 4.5 1.16
A/J f 3.84 0.351   5 0.157 0.0913 3.5, 4.2 1.39
A/J m 3.52 0.342   5 0.153 0.0972 3.0, 3.9 0.69
BALB/cJ f 2.6 0.381   5 0.17 0.146 2.2, 3.0 -0.81
BALB/cJ m 3.46 0.577   5 0.258 0.167 2.9, 4.4 0.58
C3H/HeJ f 3.76 0.41   5 0.183 0.109 3.1, 4.2 1.25
C3H/HeJ m 3.52 0.753   5 0.337 0.214 2.6, 4.7 0.69
C57BL/6J f 2.32 0.311   5 0.139 0.134 2.0, 2.8 -1.3
C57BL/6J m 2.58 0.228   5 0.102 0.0884 2.3, 2.9 -1.14
DBA/2J f 2.74 0.635   5 0.284 0.232 2.1, 3.6 -0.56
DBA/2J m 3.52 0.228   5 0.102 0.0648 3.2, 3.8 0.69
I/LnJ f 3.1 0.424   4 0.212 0.137 2.7, 3.6 0.08
I/LnJ m 2.42 0.377   5 0.169 0.156 2.0, 3.0 -1.45
MRL/MpJ-Faslpr/J f 3.6 0.7   3 0.404 0.194 2.9, 4.3 0.96
MRL/MpJ-Faslpr/J m 3.54 0.522   5 0.234 0.148 2.7, 4.1 0.73
NZB/BlNJ f 2.84 0.456   5 0.204 0.161 2.4, 3.5 -0.38
NZB/BlNJ m 2.58 0.249   5 0.111 0.0965 2.4, 3.0 -1.14
SM/J f 2.38 0.239   5 0.107 0.1 2.1, 2.7 -1.2
SM/J m 2.74 0.152   5 0.0678 0.0553 2.6, 2.9 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.38 0.1906 3.7596 3.0004
129S1/SvImJ m 3.76 0.1906 4.1396 3.3804
A/J f 3.84 0.1906 4.2196 3.4604
A/J m 3.52 0.1906 3.8996 3.1404
BALB/cJ f 2.6 0.1906 2.9796 2.2204
BALB/cJ m 3.46 0.1906 3.8396 3.0804
C3H/HeJ f 3.76 0.1906 4.1396 3.3804
C3H/HeJ m 3.52 0.1906 3.8996 3.1404
C57BL/6J f 2.32 0.1906 2.6996 1.9404
C57BL/6J m 2.58 0.1906 2.9596 2.2004
DBA/2J f 2.74 0.1906 3.1196 2.3604
DBA/2J m 3.52 0.1906 3.8996 3.1404
I/LnJ f 3.1 0.2131 3.5244 2.6756
I/LnJ m 2.42 0.1906 2.7996 2.0404
MRL/MpJ-Faslpr/J f 3.6 0.2461 4.09 3.11
MRL/MpJ-Faslpr/J m 3.54 0.1906 3.9196 3.1604
NZB/BlNJ f 2.84 0.1906 3.2196 2.4604
NZB/BlNJ m 2.58 0.1906 2.9596 2.2004
SM/J f 2.38 0.1906 2.7596 2.0004
SM/J m 2.74 0.1906 3.1196 2.3604


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.57 0.1348 3.8384 3.3016
A/J both 3.68 0.1348 3.9484 3.4116
BALB/cJ both 3.03 0.1348 3.2984 2.7616
C3H/HeJ both 3.64 0.1348 3.9084 3.3716
C57BL/6J both 2.45 0.1348 2.7184 2.1816
DBA/2J both 3.13 0.1348 3.3984 2.8616
I/LnJ both 2.76 0.143 3.0447 2.4753
MRL/MpJ-Faslpr/J both 3.57 0.1556 3.8799 3.2601
NZB/BlNJ both 2.71 0.1348 2.9784 2.4416
SM/J both 2.56 0.1348 2.8284 2.2916




  GWAS USING LINEAR MIXED MODELS