Project measure / variable:   Maurer1   heart_adjwt_iso10

ID, description, units MPD:33277   heart_adjwt_iso10   heart weight normalized to body weight   [mg/g]  isoprot 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Maurer1 - heart weight normalized to body weight isoprot 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means5.05   mg/g
Median of the strain means4.88   mg/g
SD of the strain means± 0.565
Coefficient of variation (CV)0.112
Min–max range of strain means4.18   –   6.25   mg/g
Mean sample size per strain10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 74.6307 3.3923 18.6026 < 0.0001
Residuals 215 39.2066 0.1824


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 6.25 0.915   12 0.264 0.146 5.42, 8.34 2.12
A/J m 4.96 0.23   10 0.0728 0.0464 4.65, 5.4 -0.17
AKR/J m 4.76 0.161   10 0.051 0.0339 4.46, 5.01 -0.52
BALB/cByJ m 5.43 0.298   17 0.0724 0.055 5.11, 6.32 0.67
BALB/cJ m 4.53 0.247   10 0.0781 0.0545 4.01, 4.82 -0.93
BTBR T+ Itpr3tf/J m 5.19 0.203   9 0.0677 0.0391 4.88, 5.6 0.24
C3H/HeJ m 4.18 0.11   9 0.0367 0.0263 3.98, 4.33 -1.55
C3H/HeOuJ m 4.43 0.225   11 0.0679 0.0509 3.96, 4.76 -1.11
C57BL/6J m 4.56 0.0943   8 0.0334 0.0207 4.42, 4.69 -0.88
C57BLKS/J m 4.88 0.336   10 0.106 0.0688 4.43, 5.59 -0.31
C58/J m 4.6 0.475   12 0.137 0.103 3.95, 5.3 -0.8
CBA/J m 4.6 0.239   10 0.0754 0.0519 4.26, 4.95 -0.8
DBA/2J m 5.8 0.249   9 0.0831 0.043 5.36, 6.15 1.32
FVB/NJ m 4.69 0.229   13 0.0634 0.0487 4.22, 5.03 -0.65
I/LnJ m 5.45 0.631   10 0.2 0.116 4.84, 7.04 0.7
KK/HlJ m 5.22 0.468   10 0.148 0.0897 4.82, 6.12 0.29
LP/J m 5.34 0.907   9 0.302 0.17 4.49, 7.48 0.51
NOD/ShiLtJ m 4.8 0.24   10 0.0757 0.0499 4.44, 5.21 -0.45
NZB/BlNJ m 5.2 0.216   7 0.0815 0.0415 4.95, 5.63 0.26
PL/J m 6.22 0.461   10 0.146 0.074 5.76, 7.43 2.06
SJL/J m 4.52 0.129   10 0.0408 0.0285 4.27, 4.68 -0.95
SM/J m 5.76 0.515   13 0.143 0.0895 5.31, 7.22 1.25
SWR/J m 4.88 0.613   9 0.204 0.126 4.42, 6.13 -0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 6.2542 0.1233 6.4971 6.0112
A/J m 4.958 0.135 5.2242 4.6918
AKR/J m 4.758 0.135 5.0242 4.4918
BALB/cByJ m 5.43 0.1036 5.6341 5.2259
BALB/cJ m 4.532 0.135 4.7982 4.2658
BTBR T+ Itpr3tf/J m 5.1922 0.1423 5.4728 4.9117
C3H/HeJ m 4.1844 0.1423 4.465 3.9039
C3H/HeOuJ m 4.4282 0.1288 4.682 4.1744
C57BL/6J m 4.5612 0.151 4.8588 4.2637
C57BLKS/J m 4.883 0.135 5.1492 4.6168
C58/J m 4.5975 0.1233 4.8405 4.3545
CBA/J m 4.598 0.135 4.8642 4.3318
DBA/2J m 5.8 0.1423 6.0806 5.5194
FVB/NJ m 4.6946 0.1184 4.9281 4.4612
I/LnJ m 5.448 0.135 5.7142 5.1818
KK/HlJ m 5.22 0.135 5.4862 4.9538
LP/J m 5.3356 0.1423 5.6161 5.055
NOD/ShiLtJ m 4.8 0.135 5.0662 4.5338
NZB/BlNJ m 5.1957 0.1614 5.5138 4.8776
PL/J m 6.225 0.135 6.4912 5.9588
SJL/J m 4.523 0.135 4.7892 4.2568
SM/J m 5.7569 0.1184 5.9904 5.5235
SWR/J m 4.8756 0.1423 5.1561 4.595




  GWAS USING LINEAR MIXED MODELS