Project measure / variable:   Maurer1   R_amp_iso10

ID, description, units MPD:33224   R_amp_iso10   amplitude of R-wave   [mV]  isoprot 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - amplitude of R-wave isoprot 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means0.624   mV
Median of the strain means0.666   mV
SD of the strain means± 0.205
Coefficient of variation (CV)0.329
Min–max range of strain means0.280   –   1.05   mV
Mean sample size per strain8.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 7.3785 0.3354 7.1117 < 0.0001
Residuals 177 8.3474 0.0472


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.578 0.225   12 0.065 0.39 0.34, 1.04 -0.22
A/J m 0.765 0.0636   2   0.045 0.0832 0.72, 0.81 0.69
AKR/J m 0.381 0.181   9 0.0604 0.475 0.08, 0.68 -1.18
BALB/cByJ m 0.78 0.181   4 0.0904 0.232 0.57, 1.01 0.76
BALB/cJ m 0.667 0.146   8 0.0515 0.218 0.43, 0.85 0.21
BTBR T+ Itpr3tf/J m 1.05 0.327   9 0.109 0.313 0.41, 1.4 2.08
C3H/HeJ m 0.29 0.222   9 0.0741 0.767 0.04, 0.67 -1.63
C3H/HeOuJ m 0.324 0.177   5 0.0793 0.548 0.04, 0.5 -1.46
C57BL/6J m 0.381 0.2   8 0.0705 0.523 0.19, 0.74 -1.18
C57BLKS/J m 0.442 0.261   10 0.0824 0.59 0.1, 0.89 -0.89
C58/J m 0.889 0.238   12 0.0688 0.268 0.36, 1.22 1.3
CBA/J m 0.28 0.0363   4 0.0181 0.129 0.245, 0.331 -1.68
DBA/2J m 0.822 0.324   8 0.114 0.394 0.391, 1.2 0.97
FVB/NJ m 0.747 0.194   13 0.0537 0.259 0.34, 1.0 0.6
I/LnJ m 0.766 0.206   10 0.0652 0.269 0.53, 1.14 0.69
KK/HlJ m 0.666 0.124   10 0.0393 0.186 0.53, 0.9 0.21
LP/J m 0.596 0.322   8 0.114 0.541 0.24, 1.2 -0.13
NOD/ShiLtJ m 0.695 0.205   10 0.0648 0.295 0.28, 1.01 0.35
NZB/BlNJ m 0.553 0.152   7 0.0573 0.274 0.27, 0.75 -0.34
PL/J m 0.844 0.288   10 0.0912 0.342 0.45, 1.37 1.08
SJL/J m 0.617 0.182   10 0.0576 0.295 0.33, 0.99 -0.03
SM/J m 0.513 0.151   13 0.0418 0.294 0.25, 0.86 -0.54
SWR/J m 0.696 0.118   9 0.0394 0.17 0.46, 0.83 0.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.5775 0.0627 0.7012 0.4538
A/J m 0.765 0.1536 1.068 0.462
AKR/J m 0.3811 0.0724 0.524 0.2383
BALB/cByJ m 0.78 0.1086 0.9943 0.5657
BALB/cJ m 0.6675 0.0768 0.819 0.516
BTBR T+ Itpr3tf/J m 1.0467 0.0724 1.1895 0.9038
C3H/HeJ m 0.29 0.0724 0.4329 0.1471
C3H/HeOuJ m 0.324 0.0971 0.5157 0.1323
C57BL/6J m 0.3813 0.0768 0.5328 0.2297
C57BLKS/J m 0.442 0.0687 0.5775 0.3065
C58/J m 0.8892 0.0627 1.0129 0.7655
CBA/J m 0.2802 0.1086 0.4945 0.066
DBA/2J m 0.8222 0.0768 0.9738 0.6707
FVB/NJ m 0.7469 0.0602 0.8658 0.6281
I/LnJ m 0.766 0.0687 0.9015 0.6305
KK/HlJ m 0.666 0.0687 0.8015 0.5305
LP/J m 0.5962 0.0768 0.7478 0.4447
NOD/ShiLtJ m 0.695 0.0687 0.8305 0.5595
NZB/BlNJ m 0.5529 0.0821 0.7148 0.3909
PL/J m 0.844 0.0687 0.9795 0.7085
SJL/J m 0.617 0.0687 0.7525 0.4815
SM/J m 0.5131 0.0602 0.6319 0.3942
SWR/J m 0.6956 0.0724 0.8384 0.5527




  GWAS USING LINEAR MIXED MODELS