Project measure / variable:   Schonfeld1   AUC_ITT2

ID, description, units MPD:32319   AUC_ITT2   glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast)   [AUC]  0 to 120 min  
Data set, strains Schonfeld1   inbred   10 strains     sex: both     age: 9-13wks
Procedure insulin tolerance
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  STRAIN COMPARISON PLOT
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Schonfeld1 - glucose levels, area under curve, insulin tolerance test (human insulin 0.75 U/kg bw i.p., 5h fast) 0 to 120 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains9 strains
Mean of the strain means-7932   AUC -8861   AUC
Median of the strain means-8013   AUC -8322   AUC
SD of the strain means± 2344 ± 2587
Coefficient of variation (CV)-0.296 -0.292
Min–max range of strain means-10667   –   -4804   AUC -11556   –   -3910   AUC
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9509500.2778 9509500.2778 2.9815 0.0885
strain 8 415592720.6 51949090.075 16.2876 < 0.0001
sex:strain 8 64278670.4222 8034833.8028 2.5192 0.0179
Residuals 72 229643261.6 3189489.7444


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ f -10413.0 1377.0   5 616.0 -0.132 -12525.0, -9075.0 -1.06
129X1/SvJ m -11067.0 2896.0   5 1295.0 -0.262 -14505.0, -7035.0 -0.85
AKR/J f -5416.0 851.0   5 380.0 -0.157 -6450.0, -4356.0 1.07
BALB/cByJ f -5724.0 989.0   5 442.0 -0.173 -7080.0, -4605.0 0.94
BALB/cByJ m -3910.0 1300.0   5 581.0 -0.332 -5970.0, -2550.0 1.91
C3H/HeJ f -7677.0 1098.0   5 491.0 -0.143 -8820.0, -5955.0 0.11
C3H/HeJ m -8322.0 1768.0   5 790.0 -0.212 -11220.0, -6840.0 0.21
C57BL/6ByJ f -4804.0 564.0   5 252.0 -0.117 -5335.0, -3965.0 1.33
C57BL/6ByJ m -7283.0 2196.0   5 982.0 -0.301 -10185.0, -5205.0 0.61
C57BL/6J f -10667.0 1899.0   5 849.0 -0.178 -13260.0, -8850.0 -1.17
C57BL/6J m -11238.0 2380.0   5 1064.0 -0.212 -13380.0, -7605.0 -0.92
DBA/1LacJ f -5892.0 2170.0   5 971.0 -0.368 -7530.0, -2145.0 0.87
DBA/1LacJ m -7104.0 2057.0   5 920.0 -0.29 -8940.0, -4515.0 0.68
NZB/BlNJ f -8349.0 1045.0   5 467.0 -0.125 -9600.0, -7215.0 -0.18
NZB/BlNJ m -11556.0 1601.0   5 716.0 -0.139 -13920.0, -9855.0 -1.04
PL/J f -10551.0 1142.0   5 511.0 -0.108 -12405.0, -9420.0 -1.12
PL/J m -8190.0 2416.0   5 1081.0 -0.295 -11475.0, -6045.0 0.26
SWR/J f -9824.0 1964.0   5 878.0 -0.2 -11787.0, -6816.0 -0.81
SWR/J m -11082.0 1456.0   5 651.0 -0.131 -13185.0, -9315.0 -0.86


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ f -10413.0 798.6851 -8820.8503 -12005.1497
129X1/SvJ m -11067.0 798.6851 -9474.8503 -12659.1497
BALB/cByJ f -5724.0 798.6851 -4131.8503 -7316.1497
BALB/cByJ m -3910.2 798.6851 -2318.0503 -5502.3497
C3H/HeJ f -7677.0 798.6851 -6084.8503 -9269.1497
C3H/HeJ m -8322.0 798.6851 -6729.8503 -9914.1497
C57BL/6ByJ f -4804.0 798.6851 -3211.8503 -6396.1497
C57BL/6ByJ m -7283.0 798.6851 -5690.8503 -8875.1497
C57BL/6J f -10667.0 798.6851 -9074.8503 -12259.1497
C57BL/6J m -11238.0 798.6851 -9645.8503 -12830.1497
DBA/1LacJ f -5892.0 798.6851 -4299.8503 -7484.1497
DBA/1LacJ m -7104.0 798.6851 -5511.8503 -8696.1497
NZB/BlNJ f -8349.0 798.6851 -6756.8503 -9941.1497
NZB/BlNJ m -11556.0 798.6851 -9963.8503 -13148.1497
PL/J f -10551.0 798.6851 -8958.8503 -12143.1497
PL/J m -8190.0 798.6851 -6597.8503 -9782.1497
SWR/J f -9824.2 798.6851 -8232.0503 -11416.3497
SWR/J m -11082.0 798.6851 -9489.8503 -12674.1497


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129X1/SvJ both -10740.0 564.7557 -9614.1801 -11865.8199
BALB/cByJ both -4817.1 564.7557 -3691.2801 -5942.9199
C3H/HeJ both -7999.5 564.7557 -6873.6801 -9125.3199
C57BL/6ByJ both -6043.5 564.7557 -4917.6801 -7169.3199
C57BL/6J both -10952.5 564.7557 -9826.6801 -12078.3199
DBA/1LacJ both -6498.0 564.7557 -5372.1801 -7623.8199
NZB/BlNJ both -9952.5 564.7557 -8826.6801 -11078.3199
PL/J both -9370.5 564.7557 -8244.6801 -10496.3199
SWR/J both -10453.1 564.7557 -9327.2801 -11578.9199




  GWAS USING LINEAR MIXED MODELS