Project measure / variable:   Mills1   all_micronucl_M06

ID, description, units MPD:25235   all_micronucl_M06   non-nucleated peripheral blood cells with micronuclei   [%]  at age 6mo  
Data set, strains Mills1   inbred   7 strains     sex: both     age: 26wks
Procedure chromosome instability assessment
Ontology mappings

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  STRAIN COMPARISON PLOT
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Mills1 - non-nucleated peripheral blood cells with micronuclei at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains7 strains
Mean of the strain means0.183   % 0.278   %
Median of the strain means0.188   % 0.257   %
SD of the strain means± 0.0456 ± 0.119
Coefficient of variation (CV)0.250 0.428
Min–max range of strain means0.118   –   0.243   % 0.200   –   0.540   %
Mean sample size per strain5.6   mice 5.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1086 0.1086 25.873 < 0.0001
strain 4 0.0968 0.0242 5.7632 0.0009
sex:strain 4 0.2127 0.0532 12.6685 < 0.0001
Residuals 42 0.1763 0.0042


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 0.22 0.0335   6 0.0137 0.152 0.17, 0.27 -0.49
AKR/J f 0.198 0.0271   6 0.0111 0.137 0.17, 0.25 0.33
AKR/J m 0.205 0.0164   6 0.00671 0.0802 0.18, 0.22 -0.61
BALB/cByJ f 0.243 0.0216   6 0.00882 0.0888 0.2, 0.26 1.32
BALB/cByJ m 0.263 0.0234   6 0.00955 0.0888 0.23, 0.29 -0.12
C57BL/6J m 0.257 0.0216   6 0.00882 0.0842 0.23, 0.29 -0.17
KK/HlJ f 0.167 0.0186   6 0.0076 0.112 0.14, 0.19 -0.35
KK/HlJ m 0.54 0.223   3 0.129 0.412 0.3, 0.74 2.21
NZO/HlLtJ f 0.188 0.00957   4 0.00479 0.0511 0.18, 0.2 0.11
NZO/HlLtJ m 0.2 0.02   3 0.0115 0.1 0.18, 0.22 -0.65
SM/J f 0.118 0.0117   6 0.00477 0.0988 0.1, 0.13 -1.42
SM/J m 0.258 0.113   6 0.046 0.436 0.17, 0.44 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
AKR/J f 0.1983 0.0264 0.2517 0.145
AKR/J m 0.205 0.0264 0.2584 0.1516
BALB/cByJ f 0.2433 0.0264 0.2967 0.19
BALB/cByJ m 0.2633 0.0264 0.3167 0.21
KK/HlJ f 0.1667 0.0264 0.22 0.1133
KK/HlJ m 0.54 0.0374 0.6155 0.4645
NZO/HlLtJ f 0.1875 0.0324 0.2529 0.1221
NZO/HlLtJ m 0.2 0.0374 0.2755 0.1245
SM/J f 0.1183 0.0264 0.1717 0.065
SM/J m 0.2583 0.0264 0.3117 0.205


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
AKR/J both 0.2017 0.0187 0.2394 0.1639
BALB/cByJ both 0.2533 0.0187 0.2911 0.2156
KK/HlJ both 0.3533 0.0229 0.3996 0.3071
NZO/HlLtJ both 0.1938 0.0247 0.2437 0.1438
SM/J both 0.1883 0.0187 0.2261 0.1506




  GWAS USING LINEAR MIXED MODELS