Project measure / variable:   Cheverud1   GLU_clear20_ctrl

ID, description, units MPD:17846   GLU_clear20_ctrl   glucose levels, area under curve, glucose tolerance test (serum GLU, 10% glucose i.p., 4h fast)   [AUC]  control diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   15 strains     sex: both     age: 20wks
Procedure glucose tolerance
Ontology mappings

  STRAIN COMPARISON PLOT
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Cheverud1 - glucose levels, area under curve, glucose tolerance test (serum GLU, 10% glucose i.p., 4h fast) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains15 strains
Mean of the strain means-0.0307   AUC 0.0892   AUC
Median of the strain means-0.0349   AUC 0.0721   AUC
SD of the strain means± 0.0455 ± 0.0919
Coefficient of variation (CV)-1.48 1.03
Min–max range of strain means-0.106   –   0.0356   AUC -0.0613   –   0.296   AUC
Mean sample size per strain8.4   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.0918 1.0918 56.0531 < 0.0001
strain 14 0.4603 0.0329 1.6881 0.0593
sex:strain 14 0.5119 0.0366 1.8774 0.0299
Residuals 222 4.3239 0.0195


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f -0.0474 0.106   7 0.0399 -2.23 -0.271, 0.059 -0.37
LGXSM10 m 0.0641 0.0233   7 0.0088 0.363 0.013, 0.079 -0.27
LGXSM15 f -0.0659 0.113   9 0.0377 -1.72 -0.247, 0.128 -0.77
LGXSM15 m 0.0816 0.169   10 0.0536 2.08 -0.175, 0.295 -0.08
LGXSM18 f -0.0473 0.0988   9 0.0329 -2.09 -0.176, 0.131 -0.36
LGXSM18 m 0.167 0.161   8 0.0569 0.961 0.031, 0.456 0.85
LGXSM19 f -0.0326 0.145   8 0.0514 -4.46 -0.26, 0.176 -0.04
LGXSM19 m 0.296 0.134   9 0.0447 0.453 0.098, 0.565 2.25
LGXSM20 f -0.0349 0.0754   8 0.0266 -2.16 -0.178, 0.051 -0.09
LGXSM20 m 0.048 0.205   7 0.0773 4.26 -0.175, 0.407 -0.45
LGXSM22 f 0.0334 0.193   12 0.0556 5.76 -0.213, 0.425 1.41
LGXSM22 m 0.0699 0.198   7 0.0748 2.83 -0.236, 0.409 -0.21
LGXSM23 f 0.0231 0.111   10 0.035 4.8 -0.144, 0.182 1.18
LGXSM23 m 0.139 0.153   14 0.041 1.11 -0.042, 0.461 0.54
LGXSM31 f -0.106 0.0984   3 0.0568 -0.926 -0.213, -0.019 -1.65
LGXSM31 m -0.0613 0.133   4 0.0665 -2.17 -0.253, 0.053 -1.64
LGXSM33 f -0.0293 0.103   16 0.0256 -3.5 -0.205, 0.15 0.03
LGXSM33 m 0.0989 0.177   15 0.0458 1.79 -0.173, 0.464 0.11
LGXSM38 f -0.0025 0.0725   6 0.0296 -29.0 -0.09, 0.08 0.62
LGXSM38 m 0.0369 0.104   8 0.0368 2.82 -0.082, 0.217 -0.57
LGXSM4 f 0.0356 0.125   8 0.0444 3.52 -0.168, 0.192 1.46
LGXSM4 m 0.0721 0.24   8 0.0849 3.33 -0.232, 0.527 -0.19
LGXSM45 f 0.0226 0.043   5 0.0192 1.9 -0.032, 0.074 1.17
LGXSM45 m -0.0593 0.0798   3 0.046 -1.34 -0.15, 0.0 -1.62
LGXSM46 f -0.0358 0.0728   9 0.0243 -2.03 -0.137, 0.045 -0.11
LGXSM46 m 0.133 0.164   10 0.0519 1.23 -0.067, 0.411 0.48
LGXSM48 f -0.0783 0.0809   10 0.0256 -1.03 -0.173, 0.108 -1.05
LGXSM48 m 0.0491 0.111   8 0.0393 2.27 -0.069, 0.221 -0.44
LGXSM5 f -0.0954 0.0618   8 0.0218 -0.648 -0.211, -0.032 -1.42
LGXSM5 m 0.203 0.214   6 0.0874 1.06 -0.078, 0.479 1.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f -0.0474 0.0527 0.0565 -0.1514
LGXSM10 m 0.0641 0.0527 0.1681 -0.0398
LGXSM15 f -0.0659 0.0465 0.0258 -0.1576
LGXSM15 m 0.0816 0.0441 0.1686 -0.0054
LGXSM18 f -0.0473 0.0465 0.0443 -0.139
LGXSM18 m 0.1673 0.0493 0.2645 0.07
LGXSM19 f -0.0326 0.0493 0.0646 -0.1299
LGXSM19 m 0.2961 0.0465 0.3878 0.2044
LGXSM20 f -0.0349 0.0493 0.0624 -0.1321
LGXSM20 m 0.048 0.0527 0.152 -0.056
LGXSM22 f 0.0334 0.0403 0.1128 -0.046
LGXSM22 m 0.0699 0.0527 0.1738 -0.0341
LGXSM23 f 0.0231 0.0441 0.1101 -0.0639
LGXSM23 m 0.1386 0.0373 0.2121 0.0651
LGXSM31 f -0.1063 0.0806 0.0525 -0.2651
LGXSM31 m -0.0613 0.0698 0.0763 -0.1988
LGXSM33 f -0.0293 0.0349 0.0394 -0.0981
LGXSM33 m 0.0989 0.036 0.1699 0.0279
LGXSM38 f -0.0025 0.057 0.1098 -0.1148
LGXSM38 m 0.0369 0.0493 0.1341 -0.0604
LGXSM4 f 0.0356 0.0493 0.1329 -0.0616
LGXSM4 m 0.0721 0.0493 0.1694 -0.0251
LGXSM45 f 0.0226 0.0624 0.1456 -0.1004
LGXSM45 m -0.0593 0.0806 0.0995 -0.2181
LGXSM46 f -0.0358 0.0465 0.0559 -0.1275
LGXSM46 m 0.1331 0.0441 0.2201 0.0461
LGXSM48 f -0.0783 0.0441 0.0087 -0.1653
LGXSM48 m 0.0491 0.0493 0.1464 -0.0481
LGXSM5 f -0.0954 0.0493 0.0019 -0.1926
LGXSM5 m 0.2025 0.057 0.3148 0.0902


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 0.0084 0.0373 0.0819 -0.0651
LGXSM15 both 0.0079 0.0321 0.071 -0.0553
LGXSM18 both 0.06 0.0339 0.1268 -0.0069
LGXSM19 both 0.1317 0.0339 0.1986 0.0649
LGXSM20 both 0.0066 0.0361 0.0777 -0.0646
LGXSM22 both 0.0516 0.0332 0.117 -0.0138
LGXSM23 both 0.0808 0.0289 0.1378 0.0239
LGXSM31 both -0.0838 0.0533 0.0212 -0.1888
LGXSM33 both 0.0348 0.0251 0.0842 -0.0146
LGXSM38 both 0.0172 0.0377 0.0915 -0.0571
LGXSM4 both 0.0539 0.0349 0.1226 -0.0149
LGXSM45 both -0.0184 0.051 0.0821 -0.1188
LGXSM46 both 0.0487 0.0321 0.1118 -0.0145
LGXSM48 both -0.0146 0.0331 0.0506 -0.0798
LGXSM5 both 0.0536 0.0377 0.1278 -0.0207




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA