Project measure / variable:   Cheverud1   CHOL_ctrl

ID, description, units MPD:17842   CHOL_ctrl   total cholesterol (serum CHOL)   [mg/dL]  control diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   15 strains     sex: both     age: 20-30wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Cheverud1 - total cholesterol (serum CHOL) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains15 strains
Mean of the strain means122   mg/dL 139   mg/dL
Median of the strain means125   mg/dL 145   mg/dL
SD of the strain means± 37.3 ± 33.6
Coefficient of variation (CV)0.305 0.241
Min–max range of strain means53.7   –   199   mg/dL 82.0   –   183   mg/dL
Mean sample size per strain7.9   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12242.2293 12242.2293 7.4518 0.0069
strain 13 212609.8404 16354.6031 9.955 < 0.0001
sex:strain 13 63401.1442 4877.0111 2.9686 0.0005
Residuals 199 326928.9078 1642.8588


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 111.0 34.6   7 13.1 0.313 72.1, 176.0 -0.3
LGXSM10 m 119.0 30.6   8 10.8 0.258 74.7, 168.0 -0.61
LGXSM15 f 126.0 45.5   9 15.2 0.361 63.3, 219.0 0.11
LGXSM15 m 122.0 31.5   11 9.48 0.258 82.0, 181.0 -0.52
LGXSM18 f 84.2 16.5   9 5.49 0.196 65.4, 108.0 -1.02
LGXSM18 m 93.5 30.0   8 10.6 0.321 68.2, 154.0 -1.37
LGXSM19 f 144.0 32.2   8 11.4 0.224 103.0, 202.0 0.59
LGXSM19 m 160.0 66.3   9 22.1 0.414 65.3, 275.0 0.61
LGXSM20 f 133.0 20.3   6 8.3 0.153 104.0, 156.0 0.29
LGXSM20 m 145.0 18.6   7 7.04 0.129 113.0, 173.0 0.17
LGXSM22 f 199.0 49.2   12 14.2 0.247 130.0, 304.0 2.07
LGXSM22 m 164.0 52.6   8 18.6 0.321 53.6, 232.0 0.73
LGXSM23 f 177.0 48.0   10 15.2 0.272 80.9, 254.0 1.47
LGXSM23 m 183.0 52.9   13 14.7 0.29 67.2, 244.0 1.3
LGXSM31 m 158.0 20.0   4 10.0 0.127 129.0, 175.0 0.55
LGXSM33 f 79.7 43.0   9 14.3 0.54 10.8, 160.0 -1.14
LGXSM33 m 164.0 67.3   11 20.3 0.409 79.8, 258.0 0.73
LGXSM38 f 111.0 37.7   8 13.3 0.339 59.4, 168.0 -0.3
LGXSM38 m 82.0 17.5   8 6.2 0.214 50.7, 115.0 -1.71
LGXSM4 f 132.0 27.8   7 10.5 0.211 96.9, 185.0 0.27
LGXSM4 m 182.0 30.2   8 10.7 0.166 147.0, 232.0 1.27
LGXSM45 f 53.7 17.3   4 8.63 0.322 41.9, 78.7 -1.83
LGXSM45 m 92.9 26.2   3 15.1 0.282 75.6, 123.0 -1.38
LGXSM46 f 124.0 24.5   8 8.68 0.199 102.0, 175.0 0.05
LGXSM46 m 130.0 34.0   9 11.3 0.262 59.4, 173.0 -0.28
LGXSM48 f 107.0 27.6   6 11.3 0.258 56.5, 134.0 -0.4
LGXSM48 m 176.0 46.2   7 17.4 0.262 96.0, 239.0 1.09
LGXSM5 f 127.0 38.8   8 13.7 0.306 54.6, 173.0 0.13
LGXSM5 m 120.0 32.3   6 13.2 0.268 83.4, 160.0 -0.58


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 110.6714 15.3197 140.8813 80.4616
LGXSM10 m 118.5875 14.3303 146.8462 90.3288
LGXSM15 f 126.2333 13.5107 152.8759 99.5908
LGXSM15 m 121.9091 12.2209 146.0082 97.81
LGXSM18 f 84.1556 13.5107 110.7981 57.513
LGXSM18 m 93.475 14.3303 121.7337 65.2163
LGXSM19 f 143.5 14.3303 171.7587 115.2413
LGXSM19 m 160.0889 13.5107 186.7315 133.4463
LGXSM20 f 133.0 16.5472 165.6304 100.3696
LGXSM20 m 144.5714 15.3197 174.7813 114.3616
LGXSM22 f 198.75 11.7006 221.8231 175.6769
LGXSM22 m 163.95 14.3303 192.2087 135.6913
LGXSM23 f 176.79 12.8174 202.0654 151.5146
LGXSM23 m 182.5538 11.2416 204.7218 160.3859
LGXSM33 f 79.7222 13.5107 106.3648 53.0796
LGXSM33 m 164.4455 12.2209 188.5446 140.3463
LGXSM38 f 111.2625 14.3303 139.5212 83.0038
LGXSM38 m 81.95 14.3303 110.2087 53.6913
LGXSM4 f 131.8429 15.3197 162.0527 101.633
LGXSM4 m 181.875 14.3303 210.1337 153.6163
LGXSM45 f 53.675 20.2661 93.6389 13.7111
LGXSM45 m 92.9 23.4013 139.0463 46.7537
LGXSM46 f 123.5 14.3303 151.7587 95.2413
LGXSM46 m 130.0444 13.5107 156.687 103.4019
LGXSM48 f 107.0833 16.5472 139.7137 74.453
LGXSM48 m 176.1429 15.3197 206.3527 145.933
LGXSM5 f 126.875 14.3303 155.1337 98.6163
LGXSM5 m 120.5 16.5472 153.1304 87.8696


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 114.6295 10.4887 135.3127 93.9462
LGXSM15 both 124.0712 9.1089 142.0336 106.1088
LGXSM18 both 88.8153 9.8476 108.2342 69.3963
LGXSM19 both 151.7944 9.8476 171.2134 132.3755
LGXSM20 both 138.7857 11.275 161.0196 116.5519
LGXSM22 both 181.35 9.2502 199.5909 163.1091
LGXSM23 both 179.6719 8.5244 196.4816 162.8622
LGXSM33 both 122.0838 9.1089 140.0463 104.1214
LGXSM38 both 96.6063 10.133 116.5882 76.6243
LGXSM4 both 156.8589 10.4887 177.5422 136.1757
LGXSM45 both 73.2875 15.4785 103.8104 42.7646
LGXSM46 both 126.7722 9.8476 146.1912 107.3533
LGXSM48 both 141.6131 11.275 163.8469 119.3793
LGXSM5 both 123.6875 10.9449 145.2705 102.1045




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA