Paigen1 images

Diet effects on gallstone formation and the assessment of liver morphology, plasma lipids, and atherosclerosis in 44 inbred strains of mice on high-fat atherogenic diet (not under pathogen-free conditions)   (2000)

Paigen B, Bouchard G, Carey MC
With: Johnson D, Tovbina M, Silva A, Carver T, Tracy T, McFarland C, Archer J, Whitmore H




Age 15-19 wks. Intervention: 8 wks on high-fat diet. Fasting conditions prior to sac.

In addition to the images this project provides scores for the following:
Microvacuoles are small vacuoles in hepatocyte cytoplasm, scored 1+ to 4+ in severity.
Macrovacuoles are large single vacuoles that replace hepatocyte cytoplasm, scored 1+ to 4+ in severity.
Inflammation refers to infiltrates of mixed inflammatory cells, including many neutrophils in liver scored 1+ to 4+ in severity.


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