Testing the effects of alcohol by quantitating motor incoordination using the parallel rod floor apparatus. Purpose: To quantitate the effects of alcohol in inbred strains of mice by measuring locomotor activity and motor incoordination before and after ethanol treatment.

Available measurements   Mice & strains       Protocol       Plots & tools wizard Change list style       Show varnames       Verbose listing       Display strain data     Compare 2 strains behavior — activity and motor function &ndash parallel rod floor apparatus   Crabbe5 distance traveled, 1.6mm rod, 6mm space [cm]     control and  EtOH       • day1(control 0)        • day2(control 0)        • day3(2g/kg i.p.)          EtOH dose effect comparison   8 strains   age 8-10wks Crabbe5 motor incoordination (errors/distance traveled) 1.6mm rod, 6mm space [n/cm]     control and  EtOH       • day1(control 0)        • day2(control 0)        • day3(2g/kg i.p.)          EtOH dose effect comparison   8 strains   age 7-14wks Display strain means in the above table for: select a strain 129S1/SvImJ A/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J DBA/2J FVB/NJ   Compare two strains: select strain 1 129S1/SvImJ A/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J DBA/2J FVB/NJ vs. select strain 2 129S1/SvImJ A/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J DBA/2J FVB/NJ   Compare female vs. male for: select a strain 129S1/SvImJ A/J BALB/cByJ BTBR T+ tf/J C3H/HeJ C57BL/6J DBA/2J FVB/NJ   Display overall measurement averages (all strains combined) in the above table

Notes

Kamens HM, Phillips TJ, Holstein SE, Crabbe JC. Characterization of the parallel rod floor apparatus to test motor incoordination in mice. Genes Brain Behav. 2005 Jun;4(4):253-66.     PubMed    MGI There have been no updates or corrections to the dataset since it was first released in Dec, 2006 No FVB/NJ females. Some strain means have N < 5 animals (click for table).

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The Crabbe5 project data set. Individual animal data in table format, with one row per animal and measurements organized as columns. Excel file Crabbe5 individual animal data in list format. Most or all of the same information* as the file above, but organized as one row per animal / measurement. Excel file Crabbe5 strain means, SD, SEM, N, Z-scores and other summary statistics. One row per strain / sex / measurement. Excel file These Excel files include data, descriptions, and units for all measurements listed above. Other download options are available via the Plots & Tools Wizard, above. Crabbe5 protocol document HTML Crabbe5 animal documentation HTML Supplemental data are available Click here for more info