Yuan2: Aging study: Lifespan and survival curves for 31 inbred strains of mice (2007)

Yuan R, Meng Q, Nautiyal J, Flurkey K, Tsaih SW, Krier R, Parker MG, Harrison DE, Paigen B. Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains. Proc Natl Acad Sci U S A. 2012 May 22;109(21):8224-9. Epub 2012 May 7.   PubMed 22566614     FullText

MPD accessed only those rows in the raw data set where censor=0. Animals judged to have died from unnatural causes are indicated as censor=1 and are present only in the raw data set. Strain AKR/J was omitted. Medians and other summary statistics computed from the lifespan data (one row per strain/sex) are available in the supplemental data set.

Yuan2 downloads
• Download Yuan2 project data set     one row per animal, one column per trait
• Download Yuan2 strain means, SD, N, etc.     one row per strain/sex/measure
• Yuan2 supplementary data
Participants Rong Yuan       The Jackson Laboratory Bar Harbor, ME
Cheryl Ackert-Bicknell       The Jackson Laboratory Bar Harbor, ME
Beverly Paigen       The Jackson Laboratory Bar Harbor, ME
Luanne L Peters       The Jackson Laboratory Bar Harbor, ME
With: Schultz D, Godfrey D
ContactRong Yuan     rong.yuan@jax.org     Lab web site
AffiliationJackson Laboratory Nathan Shock Center
AcknowledgementsFunding provided by NIH AG025707 (NIA Nathan Shock Center for Aging Research); The Ellison Medical Foundation
Project type Phenotype strain survey data set
MPD identifiersYuan2     MPD:234
Data changelog 1 update/correction.       Initial release date: 04/2014.
Formatted citation
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Summary of procedures that were conducted
• colony observation Life span study. Survival curves. Aging study.
Mice: inbred   31 strains   ♀♂   age various   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Yuan2 23201 colony observation (none) median lifespan   [d]  lifespan_median inbred 31 both varies
    Yuan2 23401 colony observation (none) lifespan   [d]  lifespandays inbred 31 both varies N=31
    All boxes