Mitchell1: Evaluating behavioral inhibition using a Go/No-go task in males of 15 inbred mouse strains (2010)

Gubner NR, Wilhelm CJ, Phillips TJ, Mitchell SH. Strain differences in behavioral inhibition in a Go/No-go task demonstrated using 15 inbred mouse strains. Alcohol Clin Exp Res. 2010 Aug;34(8):1353-62. Epub 2010 May 14.   PubMed 20491731  


       
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Participants Suzanne H Mitchell       Oregon Health & Science University Portland, OR
ContactSuzanne H Mitchell     mitchesu@ohsu.edu     Lab web site
AcknowledgementsFunding provided by NIH AA010760; Department of Veterans Affairs; Portland Alcohol Research Center (PARC)
Project type Phenotype strain survey data set
MPD identifiersMitchell1     MPD:376
Data changelog 1 update/correction.       Initial release date: 08/2011.
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Summary of procedures that were conducted
• go/no-go task Pre-cue, go cue. no-go cue. Discrimination index.
• monitoring system Locomotor activity.
• bottle choice test Sucrose vs. water.
Mice: inbred   15 strains   ♂   age 5-7wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Mitchell1 37603 go/no-go task (none) number of responses made during pre-cue period   [n/s]  precue_rate inbred 15 m 5-7wks N=8
    Mitchell1 37604 go/no-go task (none) ratio of Go trials with responses   [ratio]  go_response inbred 15 m 5-7wks N=8
    Mitchell1 37605 go/no-go task (none) ratio of No-go trials with responses (false alarms)   [ratio]  nogo_response inbred 15 m 5-7wks N=8
    Mitchell1 37606 go/no-go task (none) latency to respond to Go cue   [s]  go_latency inbred 15 m 5-7wks N=8
    Mitchell1 37607 go/no-go task (none) latency to respond to No-go cue   [s]  nogo_latency inbred 15 m 5-7wks N=8
    Mitchell1 37608 go/no-go task (none) ratio of responses that occurred in the target location   [ratio]  target_specific inbred 15 m 5-7wks N=8
    Mitchell1 37609 go/no-go task (none) number of rewards per total number of responses   [ratio]  efficiency inbred 15 m 5-7wks N=8
    Mitchell1 37610 go/no-go task (none) index of discrimination of Go versus No-go cues   [ratio]  discrim_index inbred 15 m 5-7wks N=8
    Mitchell1 37611 monitoring system (none) distance traveled in 15 min, day2   [cm]  activity_D2 inbred 15 m 5-7wks N=6
    Mitchell1 37617 monitoring system (none) change in locomotor activity (day2 minus day1)   [cm]  habituation inbred 15 m 5-7wks N=6
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