Koide2: Capsaicin intake and pain threshold in 14 inbred strains of mice, mostly wild-derived (Mishima) strains (2003)

Furuse T, Blizard DA, Moriwaki K, Miura Y, Yagasaki K, Shiroishi T, Koide T. Genetic diversity underlying capsaicin intake in the Mishima battery of mouse strains. Brain Res Bull. 2002 Jan 1;57(1):49-55.   PubMed 11827737  

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Participants Tsuyoshi Koide       National Institute of Genetics Mishima JAPAN
Tamio Furuse       National Institute of Genetics Mishima JAPAN
ContactTsuyoshi Koide     tkoide@lab.nig.ac.jp     Lab web site
AcknowledgementsFunding provided by Special Coordination Funds; Grant-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology (Japan)

This study is from the National Institute of Genetics, Japan (#2449)
Project type Phenotype strain survey data set
MPD identifiersKoide2     MPD:358
Data changelog No updates/corrections.       Initial release date: 02/2011.
Formatted citation
Click above to copy-paste the entire citation for this MPD web page.
Pure water consumption was measured at baseline. Then, to ascertain pain threshold, increasing amounts of capsaicin were added to drinking water. Consumption of those concentrations was measured and is expressed as a percent of the baseline pure water consumption. Mice had no other source of drinking water.

Summary of procedures that were conducted
• nociception assay Capsaicin intake at several concentrations.
Mice: wild-derived Mishima   14 strains   ♀♂   age 8-12wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Koide2 35802 nociception assay (none) capsaicin solution consumption, percent of baseline   [%]     concentration (µM):    0.5    1    4    7    10    15 wild-derived Mishima 14 both 8-12wks N=10
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