HMDPpheno3: Heart rate and blood pressure in males of 58 strains of mice (2012)

Smolock EM, Ilyushkina IA, Ghazalpour A, Gerloff J, Murashev AN, Lusis AJ, Korshunov VA. Genetic locus on mouse chromosome 7 controls elevated heart rate. Physiol Genomics. 2012 Jul 3;44(13):689-98. doi: 10.1152/physiolgenomics.00041.2012. Epub 2012 May 15.   PubMed 22589454     FullText


       
HMDPpheno3 downloads
• Download HMDPpheno3 strain means, SD, N, etc.     one row per strain/sex/measure
Participants Vyacheslav A Korshunov       University of Rochester School of Medicine and Dentistry Rochester, NY
With: Smolock EM, Ilyushkina IA, Ghazalpour A, Gerloff J, Murashev AN, Lusis AJ
ContactVyacheslav A Korshunov     Slava_Korshunov@URMC.Rochester.edu     Lab web site
AffiliationHybrid Mouse Diversity Panel Group (HMDP)
AcknowledgementsFunding provided by NIH HL105623, HL30568, HL42488; University of Rochester, Russian Program “Scientific and scientific-pedagogical personnel of innovative Russia” 14.740.11.0923
Project type Phenotype strain survey data set
MPD identifiersHMDPpheno3     MPD:453
Data changelog No updates/corrections.       Initial release date: 07/2013.
Formatted citation
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This project tested the inbred, AXB, and BXA strain subsets of the Hybrid Mouse Diversity Panel (HDP). Data can be analyzed for all strains together, or by strain panel subset.

Summary of procedures that were conducted
• tail cuff Heart rate and blood pressure. Conscious mice.
Mice: HMDP   58 strains including progenitors   ♂   age 9-10wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    HMDPpheno3 45301 tail cuff (none) pulse rate   [n/min]  HR HMDP w/par 58 m 9-10wks N=6
    HMDPpheno3 45302 tail cuff (none) systolic blood pressure   [mmHg]  BP HMDP w/par 58 m 9-10wks N=6
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