DiCurzio1: Adrenal gland weight and morphology in 64 BXD recombinant inbred strains of mice (2010)

Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav. 2010 Mar 1;9(2):129-59. Epub 2009 Sep 22.   PubMed 19958391     FullText

Di Curzio DL, Goldowitz D. The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm Genome. 2011 Apr;22(3-4):209-34. Epub 2011 Feb 24.   PubMed 21347846  


       
DiCurzio1 downloads
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• DiCurzio1 supplementary data
Participants Domenico L Di Curzio       University of Manitoba Winnipeg, Manitoba CANADA
Daniel Goldowitz       University of British Columbia Vancouver British Columbia CANADA
ContactDaniel Goldowitz     dang@cmmt.ubc.ca     Lab web site
AcknowledgementsFunding provided by NIH DA020677 and AA016666

Animals used in this study were provided primarily by Oak Ridge National Laboratory.
Project type Phenotype strain survey data set
MPD identifiersDiCurzio1     MPD:366
Data changelog No updates/corrections.       Initial release date: 04/2011.
Formatted citation
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Summary of procedures that were conducted
• body weight
• organ weights Adrenal weight.
• histopathology Adrenal glands.
Mice: BXD   66 strains including progenitors   ♀♂   age 10wks   1 cohort

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Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    DiCurzio1 36601 body weight (none) body weight at testing   [g]  bw BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 36602 organ weights (none) adrenal weights   [mg]     left    right BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 36604 organ weights (none) mean weight of both adrenals   [mg]  adr_wt_ave BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 36605 organ weights (none) total weight of adrenals adjusted to body weight (x10-3)   [mg]  adr_adj_bw BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 36606 histopathology (none) adrenal total width (diameter)   [µm]  adr_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36607 histopathology (none) adrenal medulla width   [µm]  adr_medul_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36608 histopathology (none) adrenal cortex zona glomerulosa thickness   [µm]  adr_glome_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36609 histopathology (none) adrenal cortex zona intermedia thickness   [µm]  adr_inter_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36610 histopathology (none) adrenal cortex zona fasciculata thickness   [µm]  adr_fasci_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36611 histopathology (none) adrenal cortex zona reticularis thickness   [µm]  adr_retic_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36612 histopathology (none) adrenal cortex X-zone thickness   [µm]  adr_Xzone_width BXD w/par 65 both 7-10wks* N=3
    DiCurzio1 36614 histopathology (none) presence of X-zone (0=no; 1=yes)   [score]  Xzone_presence BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 36615 histopathology (none) presence of lipoid structures in females (0=none; 1=outside X-zone; 2=within X-zone)   [score]  lipoid_presence BXD w/par 66 f 7-10wks* N=4
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