Churchill1: Bone characteristics and body composition of 63 F1-hybrid mouse strains from an 8-way diallel cross (2004)

Churchill GA, Baldwin C

       
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Participants Gary A Churchill       The Jackson Laboratory Bar Harbor, ME
Clint Baldwin       Boston University Boston, MA
ContactGary A Churchill     gary.churchill@jax.org     Lab web site
AffiliationCenter for Genome Dynamics (CGD)
Project type Phenotype strain survey data set
MPD identifiersChurchill1     MPD:171
Data changelog 1 update/correction.       Initial release date: 01/2007.
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An 8-way cross conducted as part of a pilot study for the Collaborative Cross initiative, using some different progenitor strains.

Summary of procedures that were conducted
• DXA Body mass, fat mass, lean mass, bone mineral density and content, bone area.
• organ dimensions Ear length (pinal).
• muscle weights Quadriceps muscle.
Mice: F1 8way   63 strains   ♀♂   age 7-8wks   1 cohort

Data set MPD ID Procedure / Protocol Drug or Challenge Phenotype Measure Panel No. of Strains Sex Age Sample Size (Avg)
    Churchill1 17101 DXA (none) whole body bone mineral density (BMD)   [g/cm2]  body_BMD F1 8way 63 both 7-8wks N=5
    Churchill1 17102 DXA (none) skull bone mineral density (BMD)   [g/cm2]  skull_BMD F1 8way 63 both 7-8wks N=5
    Churchill1 17103 DXA (none) vetebral spine bone mineral density (BMD)   [g/cm2]  spine_BMD F1 8way 63 both 7-8wks N=5
    Churchill1 17104 DXA (none) total tissue mass, head excluded   [g]  tissue_mass F1 8way 63 both 7-8wks N=5
    Churchill1 17105 DXA (none) weight of fat tissue, head excluded   [g]  fat_wt F1 8way 63 both 7-8wks N=5
    Churchill1 17106 DXA (none) weight of lean tissue, head excluded   [g]  lean_wt F1 8way 63 both 7-8wks N=5
    Churchill1 17107 DXA (none) percent fat, head excluded   [%]  pct_fat F1 8way 63 both 7-8wks N=5
    Churchill1 17108 organ dimensions (none) ear pinal length   [mm]  ear_length F1 8way 63 both 7-8wks N=5
    Churchill1 17109 muscle weights (none) weight of isolated quadriceps muscle   [g]  quadricep_wt F1 8way 63 both 7-8wks N=5
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