MPD: Project measures / variables set: Gershenfeld1 defecation

Project measures / variables set: Gershenfeld1 defecation

ID, description, units	MPD:16218 defecation number of fecal boli, 15 min test [n] imipramine study
Measures	• baseline • imipramine 30mg/kg
Data set, strains	Gershenfeld1 inbred 12 strains sex: m age: 5-10wks
Procedure	open field test
Comparison	control group vs. treated group
Ontology mappings	VT:0010462 defecation behavior trait VT:0010487 response to xenobiotic stimulus trait VT:0010716 anxiety-related behavior trait MP:0001362 abnormal anxiety-related response MP:0009745 abnormal behavioral response to xenobiotic MP:0020147 abnormal defecation amount

Values Means Δ Means Z-scores

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Gershenfeld1 - number of fecal boli, 15 min test

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	11.5625	11.5625	2.5813	0.1113
group:strain	11	89.8614	8.1692	1.8238	0.0594
Residuals	101	452.4071	4.4793
strain	11	454.137	41.2852	9.2169	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gershenfeld1	16218	open field test	imipramine	number of fecal boli, 15 min test [n] baseline defecation	inbred	12	m	5-10wks
Gershenfeld1	16219	open field test	imipramine	number of fecal boli, 15 min test [n] imipramine 30mg/kg defecation_Rx	inbred	12	m	5-10wks