MPD: Project measures / variables set: Gershenfeld1 LDtransits

Project measures / variables set: Gershenfeld1 LDtransits

ID, description, units	MPD:16210 LDtransits number of transitions between light and dark compartments in 10 min [n] imipramine study
Measures	• baseline • imipramine 30mg/kg
Data set, strains	Gershenfeld1 inbred 12 strains sex: m age: 5-10wks
Procedure	light-dark box
Comparison	control group vs. treated group
Ontology mappings	VT:0001392 locomotor behavior trait VT:0010487 response to xenobiotic stimulus trait VT:0010716 anxiety-related behavior trait MP:0001362 abnormal anxiety-related response MP:0001392 abnormal locomotor behavior MP:0009745 abnormal behavioral response to xenobiotic MP:0013189 abnormal exploration in a new environment

Values Means Δ Means Z-scores

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Gershenfeld1 - number of transitions between light and dark compartments in 10 min

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	84.1243	84.1243	0.8532	0.358
group:strain	11	380.8802	34.6255	0.3512	0.971
Residuals	95	9367.3675	98.6039
strain	11	38781.3255	3525.575	35.7549	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gershenfeld1	16210	light-dark box	imipramine	number of transitions between light and dark compartments in 10 min [n] baseline LDtransits	inbred	12	m	5-10wks
Gershenfeld1	16211	light-dark box	imipramine	number of transitions between light and dark compartments in 10 min [n] imipramine 30mg/kg LDtransits_Rx	inbred	12	m	5-10wks