MPD: Project measures / variables set: Auwerx2 ldl

Project measures / variables set: Auwerx2 ldl

ID, description, units	MPD:114689 ldl plasma LDL amount [mmol/L]
Measures	• CD • HFD
Data set, strains	Auwerx2 inbred w/CC8 9 strains sex: both age: 21wks
Procedure	lipid profile
Comparison	control group vs. treated group
Ontology mappings	VT:0000181 blood LDL cholesterol amount MA:0002501 plasma MP:0000181 abnormal circulating LDL cholesterol level

Values Means Δ Means Z-scores

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Auwerx2 - plasma LDL amount

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	0.0609	0.0609	50.816	< 0.0001
group:sex	1	0.0022	0.0022	1.8333	0.1786
group:sex:strain	6	0.1647	0.0274	22.9153	< 0.0001
group:strain	6	0.118	0.0197	16.4156	< 0.0001
Residuals	106	0.127	0.0012
sex	1	0.0221	0.0221	18.4383	< 0.0001
sex:strain	6	0.1421	0.0237	19.7664	< 0.0001
strain	6	0.1756	0.0293	24.4306	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Auwerx2	114689	lipid profile	(none)	plasma LDL amount [mmol/L] CD ldl_CD	inbred w/CC8	9	both	21wks
Auwerx2	114690	lipid profile	(none)	plasma LDL amount [mmol/L] HFD ldl_HFD	inbred w/CC8	9	both	21wks