Project measure / variable:   GMC16   sodium_21

ID, description, units MPD:56525   sodium_21   sodium (plasma Na)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - sodium (plasma Na) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means145   mmol/L 147   mmol/L
Median of the strain means144   mmol/L 146   mmol/L
SD of the strain means± 2.60 ± 2.36
Coefficient of variation (CV)0.0180 0.0160
Min–max range of strain means142   –   149   mmol/L 144   –   151   mmol/L
Mean sample size per strain8.9   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 177.4938 177.4938 17.3961 0.0001
strain 7 663.9358 94.848 9.296 < 0.0001
sex:strain 7 55.3887 7.9127 0.7755 0.6088
Residuals 137 1397.8222 10.2031


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 142.0 1.62   10 0.512 0.0114 140.0, 145.0 -1.06
129S1/SvImJ m 147.0 6.27   12 1.81 0.0428 141.0, 164.0 -0.05
A/J f 149.0 1.73   8 0.611 0.0116 147.0, 152.0 1.63
A/J m 151.0 1.75   8 0.62 0.0116 149.0, 154.0 1.64
C57BL/6J f 144.0 2.49   10 0.786 0.0173 141.0, 147.0 -0.29
C57BL/6J m 146.0 3.06   12 0.883 0.021 141.0, 150.0 -0.48
CAST/EiJ f 143.0 2.19   12 0.632 0.0153 137.0, 146.0 -0.67
CAST/EiJ m 144.0 2.28   10 0.722 0.0159 140.0, 147.0 -1.33
NOD/ShiLtJ f 142.0 3.27   5 1.46 0.023 137.0, 145.0 -1.06
NOD/ShiLtJ m 145.0 5.87   9 1.96 0.0404 135.0, 154.0 -0.9
NZO/HlLtJ f 145.0 3.11   8 1.1 0.0214 141.0, 149.0 0.1
NZO/HlLtJ m 146.0 2.87   10 0.907 0.0196 142.0, 150.0 -0.48
PWK/PhJ f 145.0 1.81   8 0.639 0.0125 143.0, 148.0 0.1
PWK/PhJ m 149.0 2.55   9 0.852 0.0172 144.0, 152.0 0.8
WSB/EiJ f 148.0 1.14   10 0.359 0.00768 146.0, 150.0 1.25
WSB/EiJ m 149.0 2.92   12 0.842 0.0196 142.0, 153.0 0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 142.2 1.0101 144.1974 140.2026
129S1/SvImJ m 146.5833 0.9221 148.4067 144.76
A/J f 148.875 1.1293 151.1082 146.6418
A/J m 150.75 1.1293 152.9832 148.5168
C57BL/6J f 143.8 1.0101 145.7974 141.8026
C57BL/6J m 145.5 0.9221 147.3234 143.6766
CAST/EiJ f 142.6667 0.9221 144.49 140.8433
CAST/EiJ m 143.9 1.0101 145.8974 141.9026
NOD/ShiLtJ f 142.2 1.4285 145.0248 139.3752
NOD/ShiLtJ m 145.3333 1.0647 147.4388 143.2279
NZO/HlLtJ f 145.25 1.1293 147.4832 143.0168
NZO/HlLtJ m 146.3 1.0101 148.2974 144.3026
PWK/PhJ f 145.125 1.1293 147.3582 142.8918
PWK/PhJ m 148.5556 1.0647 150.661 146.4501
WSB/EiJ f 147.8 1.0101 149.7974 145.8026
WSB/EiJ m 148.8333 0.9221 150.6567 147.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 144.3917 0.6838 145.7439 143.0394
A/J both 149.8125 0.7986 151.3916 148.2334
C57BL/6J both 144.65 0.6838 146.0023 143.2977
CAST/EiJ both 143.2833 0.6838 144.6356 141.9311
NOD/ShiLtJ both 143.7667 0.8908 145.5282 142.0051
NZO/HlLtJ both 145.775 0.7576 147.2731 144.2769
PWK/PhJ both 146.8403 0.7761 148.3749 145.3057
WSB/EiJ both 148.3167 0.6838 149.6689 146.9644




  GWAS USING LINEAR MIXED MODELS