Project measure / variable:   GMC16   potassium_21

ID, description, units MPD:56523   potassium_21   potassium (plasma K)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - potassium (plasma K) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means4.08   mmol/L 4.29   mmol/L
Median of the strain means4.13   mmol/L 4.34   mmol/L
SD of the strain means± 0.189 ± 0.219
Coefficient of variation (CV)0.0462 0.0510
Min–max range of strain means3.68   –   4.27   mmol/L 3.93   –   4.53   mmol/L
Mean sample size per strain8.9   mice 9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6669 1.6669 10.0736 0.0019
strain 7 2.6781 0.3826 2.3121 0.0295
sex:strain 7 2.3718 0.3388 2.0477 0.0536
Residuals 133 22.0077 0.1655


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.26 0.706   9 0.235 0.166 3.4, 5.5 0.93
129S1/SvImJ m 4.05 0.45   10 0.142 0.111 3.3, 4.6 -1.09
A/J f 4.15 0.455   10 0.144 0.11 3.5, 4.8 0.35
A/J m 4.43 0.403   11 0.121 0.091 3.7, 5.1 0.65
C57BL/6J f 3.68 0.326   10 0.103 0.0886 2.9, 4.1 -2.14
C57BL/6J m 4.26 0.442   12 0.128 0.104 3.5, 5.4 -0.13
CAST/EiJ f 4.16 0.207   10 0.0653 0.0497 3.8, 4.4 0.4
CAST/EiJ m 4.53 0.315   7 0.119 0.0695 3.9, 4.8 1.11
NOD/ShiLtJ f 4.27 0.412   9 0.137 0.0966 3.8, 4.8 0.99
NOD/ShiLtJ m 4.46 0.317   11 0.0956 0.071 3.9, 5.1 0.79
NZO/HlLtJ f 4.05 0.758   6 0.31 0.187 3.2, 5.0 -0.18
NZO/HlLtJ m 3.93 0.493   6 0.201 0.125 3.5, 4.7 -1.63
PWK/PhJ f 3.99 0.308   7 0.116 0.0772 3.6, 4.4 -0.5
PWK/PhJ m 4.46 0.313   9 0.104 0.0702 4.1, 5.0 0.79
WSB/EiJ f 4.11 0.256   10 0.0809 0.0622 3.7, 4.5 0.14
WSB/EiJ m 4.18 0.147   12 0.0423 0.0351 4.0, 4.4 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.2556 0.1356 4.5238 3.9874
129S1/SvImJ m 4.05 0.1286 4.3044 3.7956
A/J f 4.15 0.1286 4.4044 3.8956
A/J m 4.4273 0.1226 4.6699 4.1847
C57BL/6J f 3.68 0.1286 3.9344 3.4256
C57BL/6J m 4.2583 0.1174 4.4906 4.0261
CAST/EiJ f 4.16 0.1286 4.4144 3.9056
CAST/EiJ m 4.5286 0.1537 4.8327 4.2245
NOD/ShiLtJ f 4.2667 0.1356 4.5349 3.9985
NOD/ShiLtJ m 4.4636 0.1226 4.7062 4.221
NZO/HlLtJ f 4.05 0.1661 4.3785 3.7215
NZO/HlLtJ m 3.9333 0.1661 4.2618 3.6049
PWK/PhJ f 3.9857 0.1537 4.2898 3.6816
PWK/PhJ m 4.4556 0.1356 4.7238 4.1874
WSB/EiJ f 4.11 0.1286 4.3644 3.8556
WSB/EiJ m 4.1833 0.1174 4.4156 3.9511


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.1528 0.0935 4.3376 3.9679
A/J both 4.2886 0.0889 4.4644 4.1129
C57BL/6J both 3.9692 0.0871 4.1414 3.7969
CAST/EiJ both 4.3443 0.1002 4.5425 4.146
NOD/ShiLtJ both 4.3652 0.0914 4.546 4.1843
NZO/HlLtJ both 3.9917 0.1174 4.2239 3.7594
PWK/PhJ both 4.2206 0.1025 4.4234 4.0179
WSB/EiJ both 4.1467 0.0871 4.3189 3.9744




  GWAS USING LINEAR MIXED MODELS