Project measure / variable:   GMC16   chloride_21

ID, description, units MPD:56513   chloride_21   chloride (plasma Cl)   [mmol/L]  at age 20-21wks  
Data set, strains GMC16   inbred w/CC8   8 strains     sex: both     age: 20-21wks
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  STRAIN COMPARISON PLOT
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GMC16 - chloride (plasma Cl) at age 20-21wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means109   mmol/L 108   mmol/L
Median of the strain means109   mmol/L 108   mmol/L
SD of the strain means± 3.02 ± 2.64
Coefficient of variation (CV)0.0277 0.0245
Min–max range of strain means104   –   113   mmol/L 103   –   111   mmol/L
Mean sample size per strain10.1   mice 11.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 71.5161 71.5161 9.5087 0.0024
strain 7 1112.324 158.9034 21.1276 < 0.0001
sex:strain 7 97.9291 13.9899 1.8601 0.0796
Residuals 158 1188.3389 7.5211


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 108.0 1.22   10 0.386 0.0113 107.0, 111.0 -0.33
129S1/SvImJ m 107.0 4.7   12 1.36 0.044 102.0, 120.0 -0.33
A/J f 109.0 1.41   10 0.446 0.0129 106.0, 111.0 0.0
A/J m 109.0 1.28   11 0.386 0.0118 107.0, 110.0 0.43
C57BL/6J f 109.0 1.52   10 0.482 0.014 106.0, 112.0 0.0
C57BL/6J m 107.0 1.84   12 0.533 0.0173 104.0, 109.0 -0.33
CAST/EiJ f 113.0 2.6   12 0.752 0.0231 106.0, 115.0 1.32
CAST/EiJ m 111.0 1.8   11 0.542 0.0162 107.0, 113.0 1.18
NOD/ShiLtJ f 104.0 5.48   9 1.83 0.0529 94.1, 112.0 -1.65
NOD/ShiLtJ m 106.0 3.41   12 0.986 0.0322 98.1, 109.0 -0.71
NZO/HlLtJ f 106.0 2.83   10 0.894 0.0267 102.0, 110.0 -0.99
NZO/HlLtJ m 103.0 3.8   12 1.1 0.0369 98.0, 109.0 -1.84
PWK/PhJ f 111.0 0.901   10 0.285 0.00815 109.0, 112.0 0.66
PWK/PhJ m 110.0 2.62   11 0.791 0.0238 106.0, 113.0 0.8
WSB/EiJ f 112.0 1.26   10 0.399 0.0113 110.0, 114.0 0.99
WSB/EiJ m 110.0 1.97   12 0.568 0.0178 107.0, 114.0 0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 108.39 0.8672 110.1029 106.6771
129S1/SvImJ m 106.8833 0.7917 108.447 105.3197
A/J f 108.98 0.8672 110.6929 107.2671
A/J m 108.6273 0.8269 110.2604 106.9941
C57BL/6J f 108.89 0.8672 110.6029 107.1771
C57BL/6J m 106.525 0.7917 108.0886 104.9614
CAST/EiJ f 112.575 0.7917 114.1386 111.0114
CAST/EiJ m 110.8091 0.8269 112.4423 109.1759
NOD/ShiLtJ f 103.6889 0.9142 105.4944 101.8833
NOD/ShiLtJ m 105.975 0.7917 107.5386 104.4114
NZO/HlLtJ f 105.92 0.8672 107.6329 104.2071
NZO/HlLtJ m 102.9167 0.7917 104.4803 101.353
PWK/PhJ f 110.55 0.8672 112.2629 108.8371
PWK/PhJ m 110.2455 0.8269 111.8786 108.6123
WSB/EiJ f 111.78 0.8672 113.4929 110.0671
WSB/EiJ m 110.3 0.7917 111.8636 108.7364


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 107.6367 0.5871 108.7963 106.477
A/J both 108.8036 0.5991 109.987 107.6203
C57BL/6J both 107.7075 0.5871 108.8671 106.5479
CAST/EiJ both 111.692 0.5724 112.8226 110.5615
NOD/ShiLtJ both 104.8319 0.6047 106.0262 103.6377
NZO/HlLtJ both 104.4183 0.5871 105.578 103.2587
PWK/PhJ both 110.3977 0.5991 111.5811 109.2144
WSB/EiJ both 111.04 0.5871 112.1996 109.8804




  GWAS USING LINEAR MIXED MODELS