Project measure / variable:   GMC14   lens_mean_density_L

ID, description, units MPD:56335   lens_mean_density_L   mean density value of lens, Scheimpflug imaging   [%]  left eye  
Data set, strains GMC14   inbred w/CC8   8 strains     sex: both     age: 15-16wks
Procedure Scheimpflug imaging
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  STRAIN COMPARISON PLOT
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GMC14 - mean density value of lens, Scheimpflug imaging left eye



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means6.25   % 6.23   %
Median of the strain means5.61   % 5.68   %
SD of the strain means± 1.33 ± 1.39
Coefficient of variation (CV)0.213 0.223
Min–max range of strain means5.08   –   9.00   % 5.09   –   9.03   %
Mean sample size per strain13.5   mice 12.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1252 0.1252 0.1562 0.6931
strain 7 382.5215 54.6459 68.1796 < 0.0001
sex:strain 7 2.9153 0.4165 0.5196 0.8191
Residuals 194 155.4908 0.8015


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.92 0.653   16 0.163 0.0944 5.9, 8.1 0.5
129S1/SvImJ m 7.19 0.989   16 0.247 0.137 5.9, 9.7 0.69
A/J f 9.0 1.48   16 0.371 0.165 6.9, 11.4 2.07
A/J m 9.03 1.68   15 0.433 0.186 7.0, 11.9 2.02
C57BL/6J f 5.6 0.935   16 0.234 0.167 4.7, 8.6 -0.49
C57BL/6J m 5.11 0.447   16 0.112 0.0874 4.4, 6.1 -0.81
CAST/EiJ f 5.38 0.947   19 0.217 0.176 4.3, 8.1 -0.65
CAST/EiJ m 5.18 0.931   16 0.233 0.18 3.7, 7.7 -0.76
NOD/ShiLtJ f 7.05 0.693   16 0.173 0.0983 6.2, 8.5 0.6
NOD/ShiLtJ m 6.9 0.621   16 0.155 0.09 6.0, 8.4 0.48
NZO/HlLtJ f 5.08 0.281   17 0.0682 0.0553 4.6, 5.6 -0.88
NZO/HlLtJ m 5.09 0.282   17 0.0683 0.0553 4.6, 5.6 -0.82
PWK/PhJ f 5.35 0.379   4 0.189 0.0708 5.1, 5.9 -0.68
PWK/PhJ m 5.65 0.0707   2   0.05 0.0125 5.6, 5.7 -0.42
WSB/EiJ f 5.62 0.263   4 0.131 0.0468 5.4, 5.9 -0.47
WSB/EiJ m 5.7 0.44   4 0.22 0.0771 5.2, 6.2 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.9187 0.2238 7.3602 6.4773
129S1/SvImJ m 7.1937 0.2238 7.6352 6.7523
A/J f 9.0 0.2238 9.4414 8.5586
A/J m 9.0333 0.2312 9.4892 8.5774
C57BL/6J f 5.6 0.2238 6.0414 5.1586
C57BL/6J m 5.1125 0.2238 5.5539 4.6711
CAST/EiJ f 5.3842 0.2054 5.7893 4.9791
CAST/EiJ m 5.1812 0.2238 5.6227 4.7398
NOD/ShiLtJ f 7.05 0.2238 7.4914 6.6086
NOD/ShiLtJ m 6.9 0.2238 7.3414 6.4586
NZO/HlLtJ f 5.0824 0.2171 5.5106 4.6541
NZO/HlLtJ m 5.0941 0.2171 5.5224 4.6659
PWK/PhJ f 5.35 0.4476 6.2329 4.4671
PWK/PhJ m 5.65 0.633 6.8985 4.4015
WSB/EiJ f 5.625 0.4476 6.5079 4.7421
WSB/EiJ m 5.7 0.4476 6.5829 4.8171


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.0562 0.1583 7.3684 6.7441
A/J both 9.0167 0.1609 9.334 8.6994
C57BL/6J both 5.3562 0.1583 5.6684 5.0441
CAST/EiJ both 5.2827 0.1519 5.5823 4.9832
NOD/ShiLtJ both 6.975 0.1583 7.2871 6.6629
NZO/HlLtJ both 5.0882 0.1535 5.3911 4.7854
PWK/PhJ both 5.5 0.3877 6.2646 4.7354
WSB/EiJ both 5.6625 0.3165 6.2868 5.0382




  GWAS USING LINEAR MIXED MODELS