Project measure / variable:   GMC05   ASR_ISI_100

ID, description, units MPD:55443   ASR_ISI_100   acoustic startle response (ASR)   [amplitude]  PP2 inter-stimulus interval: 100  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) PP2 inter-stimulus interval: 100



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means585   amplitude 750   amplitude
Median of the strain means304   amplitude 414   amplitude
SD of the strain means± 704 ± 758
Coefficient of variation (CV)1.20 1.01
Min–max range of strain means188   –   2283   amplitude 261   –   2488   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1947555.0026 1947555.0026 26.8611 < 0.0001
strain 7 119345271.8938 17049324.5563 235.1481 < 0.0001
sex:strain 7 1400441.9472 200063.1353 2.7593 0.0089
Residuals 250 18126155.2865 72504.6211


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 682.0 280.0   16 70.1 0.411 331.0, 1355.0 0.14
129S1/SvImJ m 1136.0 346.0   16 86.6 0.305 505.0, 1704.0 0.51
A/J f 202.0 142.0   16 35.5 0.703 50.6, 593.0 -0.54
A/J m 261.0 125.0   16 31.3 0.481 86.7, 533.0 -0.65
C57BL/6J f 309.0 172.0   16 42.9 0.555 128.0, 746.0 -0.39
C57BL/6J m 650.0 210.0   16 52.5 0.323 343.0, 1047.0 -0.13
CAST/EiJ f 300.0 86.4   19 19.8 0.288 210.0, 491.0 -0.41
CAST/EiJ m 402.0 143.0   18 33.7 0.355 165.0, 650.0 -0.46
NOD/ShiLtJ f 188.0 88.6   18 20.9 0.472 79.8, 387.0 -0.56
NOD/ShiLtJ m 268.0 173.0   16 43.4 0.646 101.0, 694.0 -0.64
NZO/HlLtJ f 2283.0 635.0   16 159.0 0.278 1153.0, 3357.0 2.41
NZO/HlLtJ m 2488.0 582.0   16 146.0 0.234 1625.0, 3362.0 2.29
PWK/PhJ f 295.0 68.1   16 17.0 0.231 173.0, 420.0 -0.41
PWK/PhJ m 370.0 99.9   17 24.2 0.27 214.0, 597.0 -0.5
WSB/EiJ f 423.0 233.0   18 55.0 0.551 177.0, 968.0 -0.23
WSB/EiJ m 426.0 103.0   16 25.7 0.241 312.0, 753.0 -0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 682.2063 67.3167 814.7864 549.6261
129S1/SvImJ m 1135.8688 67.3167 1268.4489 1003.2886
A/J f 202.2375 67.3167 334.8176 69.6574
A/J m 260.5188 67.3167 393.0989 127.9386
C57BL/6J f 309.45 67.3167 442.0301 176.8699
C57BL/6J m 649.6875 67.3167 782.2676 517.1074
CAST/EiJ f 299.7737 61.774 421.4376 178.1098
CAST/EiJ m 401.9056 63.4668 526.9033 276.9078
NOD/ShiLtJ f 187.5667 63.4668 312.5644 62.5689
NOD/ShiLtJ m 268.325 67.3167 400.9051 135.7449
NZO/HlLtJ f 2283.2063 67.3167 2415.7864 2150.6261
NZO/HlLtJ m 2487.7938 67.3167 2620.3739 2355.2136
PWK/PhJ f 294.675 67.3167 427.2551 162.0949
PWK/PhJ m 369.8176 65.3068 498.4393 241.196
WSB/EiJ f 423.3278 63.4668 548.3255 298.33
WSB/EiJ m 426.3875 67.3167 558.9676 293.8074


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 909.0375 47.6001 1002.7858 815.2892
A/J both 231.3781 47.6001 325.1264 137.6298
C57BL/6J both 479.5688 47.6001 573.3171 385.8204
CAST/EiJ both 350.8396 44.2834 438.0556 263.6236
NOD/ShiLtJ both 227.9458 46.259 319.0528 136.8388
NZO/HlLtJ both 2385.5 47.6001 2479.2483 2291.7517
PWK/PhJ both 332.2463 46.8949 424.6057 239.8869
WSB/EiJ both 424.8576 46.259 515.9646 333.7506




  GWAS USING LINEAR MIXED MODELS