Project measure / variable:   GMC02   all_paws3

ID, description, units MPD:55123   all_paws3   forelimb and hindlimb grip strength   [g]  trial3  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb and hindlimb grip strength trial3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means187   g 206   g
Median of the strain means189   g 220   g
SD of the strain means± 30.4 ± 37.9
Coefficient of variation (CV)0.163 0.184
Min–max range of strain means150   –   231   g 157   –   248   g
Mean sample size per strain17.4   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 23154.732 23154.732 39.1839 < 0.0001
strain 7 268403.2889 38343.327 64.887 < 0.0001
sex:strain 7 14852.9173 2121.8453 3.5907 0.001
Residuals 258 152458.5655 590.9247


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 174.0 15.3   16 3.83 0.0881 143.0, 197.0 -0.42
129S1/SvImJ m 223.0 15.7   16 3.94 0.0706 187.0, 258.0 0.46
A/J f 204.0 34.8   16 8.69 0.17 157.0, 279.0 0.57
A/J m 219.0 21.2   16 5.31 0.0969 184.0, 255.0 0.36
C57BL/6J f 213.0 25.9   16 6.46 0.122 170.0, 262.0 0.87
C57BL/6J m 248.0 33.8   16 8.45 0.137 202.0, 311.0 1.12
CAST/EiJ f 160.0 19.1   19 4.38 0.12 136.0, 194.0 -0.88
CAST/EiJ m 157.0 19.1   17 4.62 0.121 116.0, 191.0 -1.28
NOD/ShiLtJ f 231.0 34.0   18 8.01 0.147 175.0, 279.0 1.46
NOD/ShiLtJ m 247.0 37.3   16 9.33 0.151 118.0, 287.0 1.09
NZO/HlLtJ f 205.0 16.6   17 4.02 0.081 174.0, 237.0 0.61
NZO/HlLtJ m 221.0 23.6   17 5.72 0.107 162.0, 255.0 0.41
PWK/PhJ f 156.0 20.2   19 4.62 0.129 124.0, 195.0 -1.01
PWK/PhJ m 171.0 17.2   21 3.74 0.1 144.0, 207.0 -0.91
WSB/EiJ f 150.0 21.2   18 4.99 0.141 100.0, 189.0 -1.21
WSB/EiJ m 158.0 20.2   16 5.05 0.128 100.0, 178.0 -1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 173.8125 6.0772 185.7798 161.8452
129S1/SvImJ m 222.9375 6.0772 234.9048 210.9702
A/J f 204.1875 6.0772 216.1548 192.2202
A/J m 219.125 6.0772 231.0923 207.1577
C57BL/6J f 212.5625 6.0772 224.5298 200.5952
C57BL/6J m 247.5625 6.0772 259.5298 235.5952
CAST/EiJ f 159.5789 5.5769 170.5609 148.597
CAST/EiJ m 157.4706 5.8958 169.0806 145.8606
NOD/ShiLtJ f 231.4444 5.7297 242.7273 220.1616
NOD/ShiLtJ m 246.75 6.0772 258.7173 234.7827
NZO/HlLtJ f 204.8235 5.8958 216.4335 193.2135
NZO/HlLtJ m 221.0588 5.8958 232.6688 209.4488
PWK/PhJ f 155.7895 5.5769 166.7714 144.8075
PWK/PhJ m 171.0952 5.3046 181.5412 160.6493
WSB/EiJ f 150.3333 5.7297 161.6162 139.0505
WSB/EiJ m 157.8125 6.0772 169.7798 145.8452


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 198.375 4.2973 206.8372 189.9128
A/J both 211.6563 4.2973 220.1184 203.1941
C57BL/6J both 230.0625 4.2973 238.5247 221.6003
CAST/EiJ both 158.5248 4.0578 166.5153 150.5342
NOD/ShiLtJ both 239.0972 4.1762 247.321 230.8735
NZO/HlLtJ both 212.9412 4.1689 221.1507 204.7317
PWK/PhJ both 163.4424 3.8484 171.0206 155.8641
WSB/EiJ both 154.0729 4.1762 162.2967 145.8492




  GWAS USING LINEAR MIXED MODELS