Project measure / variable:   Harrill2   kidney_DB75_trt

ID, description, units MPD:44156   kidney_DB75_trt   kidney metabolite (DB75) concentration   [µM]  DB289  
DB289 study
Data set, strains Harrill2   inbred   34 strains     sex: f     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Harrill2 - kidney metabolite (DB75) concentration DB289



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested34 strains
Mean of the strain means1033   µM
Median of the strain means1012   µM
SD of the strain means± 314
Coefficient of variation (CV)0.304
Min–max range of strain means555   –   1816   µM
Mean sample size per strain5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 16153753.8714 489507.6931 25.1898 < 0.0001
Residuals 134 2603988.2 19432.7478


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 969.0 45.8   5 20.5 0.0472 895.0, 1006.0 -0.2
A/J f 1199.0 26.5   5 11.9 0.0221 1162.0, 1234.0 0.53
AKR/J f 1043.0 157.0   5 70.2 0.15 856.0, 1204.0 0.03
BALB/cByJ f 1045.0 125.0   5 56.0 0.12 895.0, 1177.0 0.04
BTBR T+ Itpr3tf/J f 1028.0 115.0   5 51.2 0.111 907.0, 1186.0 -0.01
BUB/BnJ f 568.0 38.6   5 17.3 0.0679 526.0, 613.0 -1.48
C3H/HeJ f 1423.0 223.0   5 99.6 0.157 1270.0, 1814.0 1.24
C57BL/6J f 1816.0 333.0   5 149.0 0.184 1511.0, 2384.0 2.5
C57BLKS/J f 1570.0 141.0   5 62.9 0.0897 1444.0, 1808.0 1.71
C57BR/cdJ f 1322.0 135.0   4 67.7 0.102 1174.0, 1477.0 0.92
C58/J f 1750.0 180.0   5 80.3 0.103 1514.0, 1973.0 2.29
CBA/J f 1272.0 326.0   5 146.0 0.257 748.0, 1553.0 0.76
CE/J f 1386.0 63.4   5 28.4 0.0457 1324.0, 1477.0 1.13
DBA/2J f 842.0 120.0   5 53.8 0.143 715.0, 1024.0 -0.61
FVB/NJ f 591.0 94.9   5 42.4 0.161 483.0, 724.0 -1.41
I/LnJ f 927.0 59.0   5 26.4 0.0636 862.0, 1018.0 -0.34
KK/HlJ f 930.0 107.0   5 47.8 0.115 844.0, 1099.0 -0.33
LG/J f 1182.0 55.4   5 24.8 0.0469 1108.0, 1255.0 0.48
LP/J f 1154.0 115.0   5 51.2 0.0993 1030.0, 1339.0 0.39
MA/MyJ f 851.0 130.0   5 58.4 0.153 706.0, 1039.0 -0.58
MRL/MpJ f 996.0 105.0   5 46.8 0.105 829.0, 1087.0 -0.12
NOD/ShiLtJ f 659.0 78.4   5 35.1 0.119 571.0, 748.0 -1.19
NON/ShiLtJ f 951.0 77.3   5 34.6 0.0812 868.0, 1036.0 -0.26
NOR/LtJ f 816.0 141.0   5 63.1 0.173 655.0, 988.0 -0.69
NZW/LacJ f 806.0 98.5   5 44.0 0.122 655.0, 928.0 -0.72
P/J f 799.0 159.0   5 71.0 0.199 625.0, 973.0 -0.74
PL/J f 1071.0 147.0   5 65.6 0.137 871.0, 1258.0 0.12
PWK/PhJ f 617.0 35.7   5 15.9 0.0578 580.0, 664.0 -1.32
RIIIS/J f 555.0 46.4   5 20.7 0.0836 474.0, 589.0 -1.52
SEA/GnJ f 1104.0 117.0   5 52.2 0.106 937.0, 1267.0 0.23
SJL/J f 714.0 106.0   5 47.4 0.148 613.0, 868.0 -1.02
SM/J f 1061.0 129.0   5 57.5 0.121 949.0, 1228.0 0.09
SWR/J f 916.0 78.3   4 39.2 0.0855 823.0, 1003.0 -0.37
WSB/EiJ f 1176.0 190.0   5 84.8 0.161 916.0, 1441.0 0.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 969.4 62.3422 1092.702 846.098
A/J f 1198.6 62.3422 1321.902 1075.298
AKR/J f 1042.6 62.3422 1165.902 919.298
BALB/cByJ f 1045.0 62.3422 1168.302 921.698
BTBR T+ Itpr3tf/J f 1027.6 62.3422 1150.902 904.298
BUB/BnJ f 568.0 62.3422 691.302 444.698
C3H/HeJ f 1422.6 62.3422 1545.902 1299.298
C57BL/6J f 1815.8 62.3422 1939.102 1692.498
C57BLKS/J f 1569.6 62.3422 1692.902 1446.298
C57BR/cdJ f 1322.5 69.7007 1460.3558 1184.6442
C58/J f 1750.4 62.3422 1873.702 1627.098
CBA/J f 1271.6 62.3422 1394.902 1148.298
CE/J f 1386.4 62.3422 1509.702 1263.098
DBA/2J f 842.2 62.3422 965.502 718.898
FVB/NJ f 590.6 62.3422 713.902 467.298
I/LnJ f 927.4 62.3422 1050.702 804.098
KK/HlJ f 930.4 62.3422 1053.702 807.098
LG/J f 1181.8 62.3422 1305.102 1058.498
LP/J f 1153.6 62.3422 1276.902 1030.298
MA/MyJ f 850.6 62.3422 973.902 727.298
MRL/MpJ f 996.4 62.3422 1119.702 873.098
NOD/ShiLtJ f 658.6 62.3422 781.902 535.298
NON/ShiLtJ f 951.4 62.3422 1074.702 828.098
NOR/LtJ f 816.4 62.3422 939.702 693.098
NZW/LacJ f 806.2 62.3422 929.502 682.898
P/J f 799.0 62.3422 922.302 675.698
PL/J f 1071.4 62.3422 1194.702 948.098
PWK/PhJ f 617.2 62.3422 740.502 493.898
RIIIS/J f 555.2 62.3422 678.502 431.898
SEA/GnJ f 1104.4 62.3422 1227.702 981.098
SJL/J f 713.8 62.3422 837.102 590.498
SM/J f 1061.2 62.3422 1184.502 937.898
SWR/J f 916.0 69.7007 1053.8558 778.1442
WSB/EiJ f 1175.8 62.3422 1299.102 1052.498




  GWAS USING LINEAR MIXED MODELS