Project measure / variable:   Donahue5   pct_CD8

ID, description, units MPD:41412   pct_CD8   CD8 T cells (percentage of viable WBC)   [%]  
Data set, strains Donahue5   B6.A consomic w/par   22 strains     sex: both     age: 7wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Donahue5 - CD8 T cells (percentage of viable WBC)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested22 strains22 strains
Mean of the strain means9.32   % 7.67   %
Median of the strain means8.91   % 7.20   %
SD of the strain means± 3.30 ± 2.91
Coefficient of variation (CV)0.354 0.380
Min–max range of strain means4.23   –   19.5   % 3.94   –   17.0   %
Mean sample size per strain8.4   mice 8.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 266.7317 266.7317 32.0037 < 0.0001
strain 21 3305.0551 157.3836 18.8836 < 0.0001
sex:strain 21 112.9672 5.3794 0.6454 0.8838
Residuals 341 2842.0294 8.3344


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 6.37 1.27   16 0.318 0.2 4.22, 9.79 -0.89
A/J m 3.94 1.49   16 0.372 0.378 1.58, 6.3 -1.28
B6.A-Chr1 f 9.51 0.902   8 0.319 0.0949 8.3, 10.7 0.06
B6.A-Chr1 m 7.5 0.812   8 0.287 0.108 6.3, 8.58 -0.06
B6.A-Chr10 f 9.56 7.7   8 2.72 0.806 1.7, 19.2 0.07
B6.A-Chr10 m 6.4 5.08   8 1.8 0.794 1.02, 12.7 -0.44
B6.A-Chr11 f 7.52 4.63   8 1.64 0.615 2.83, 12.9 -0.55
B6.A-Chr11 m 7.54 2.37   8 0.837 0.314 3.33, 10.1 -0.04
B6.A-Chr12 f 9.02 0.98   8 0.347 0.109 7.22, 10.2 -0.09
B6.A-Chr12 m 6.61 1.27   8 0.451 0.193 4.93, 8.26 -0.36
B6.A-Chr13 f 14.0 2.92   8 1.03 0.209 10.0, 17.4 1.42
B6.A-Chr13 m 12.4 3.53   8 1.25 0.284 8.15, 18.9 1.62
B6.A-Chr14 f 8.74 5.44   8 1.92 0.623 3.08, 14.7 -0.18
B6.A-Chr14 m 8.8 4.14   8 1.47 0.471 3.86, 13.2 0.39
B6.A-Chr15 f 6.54 2.26   8 0.797 0.345 1.15, 8.1 -0.84
B6.A-Chr15 m 6.15 0.789   8 0.279 0.128 5.36, 7.8 -0.52
B6.A-Chr16 f 8.39 1.51   8 0.534 0.18 6.96, 11.2 -0.28
B6.A-Chr16 m 6.92 1.84   8 0.65 0.266 2.81, 8.49 -0.26
B6.A-Chr17 f 19.5 2.53   8 0.893 0.13 15.6, 23.7 3.09
B6.A-Chr17 m 17.0 3.16   8 1.12 0.186 13.4, 20.9 3.2
B6.A-Chr18 f 12.0 6.79   8 2.4 0.566 3.93, 20.7 0.81
B6.A-Chr18 m 9.43 3.69   8 1.31 0.392 4.69, 14.7 0.6
B6.A-Chr19 f 12.1 3.11   8 1.1 0.258 8.29, 16.7 0.84
B6.A-Chr19 m 10.1 1.67   8 0.59 0.165 7.23, 12.5 0.83
B6.A-Chr2 f 9.81 1.92   9 0.641 0.196 7.35, 13.7 0.15
B6.A-Chr2 m 7.68 2.32   8 0.82 0.302 2.87, 10.3 0.0
B6.A-Chr3 f 10.5 5.36   8 1.89 0.511 5.16, 17.3 0.36
B6.A-Chr3 m 7.26 3.33   8 1.18 0.459 3.52, 13.6 -0.14
B6.A-Chr4 f 9.15 0.674   8 0.238 0.0736 8.21, 9.94 -0.05
B6.A-Chr4 m 5.64 0.695   8 0.246 0.123 4.35, 6.48 -0.7
B6.A-Chr5 f 4.23 0.762   8 0.269 0.18 3.0, 5.3 -1.54
B6.A-Chr5 m 3.98 0.562   8 0.199 0.141 3.16, 4.63 -1.27
B6.A-Chr6 f 11.9 1.27   8 0.449 0.106 10.7, 14.8 0.78
B6.A-Chr6 m 9.83 0.679   8 0.24 0.0691 8.73, 10.8 0.74
B6.A-Chr7 f 4.69 2.52   8 0.892 0.538 1.75, 8.18 -1.4
B6.A-Chr7 m 4.18 2.19   8 0.773 0.523 1.41, 8.23 -1.2
B6.A-Chr8 f 6.87 4.04   8 1.43 0.588 2.56, 11.7 -0.74
B6.A-Chr8 m 6.57 3.13   8 1.11 0.476 2.72, 10.6 -0.38
B6.A-Chr9 f 7.29 1.71   8 0.606 0.235 4.02, 9.07 -0.62
B6.A-Chr9 m 7.13 1.5   8 0.532 0.211 4.22, 8.85 -0.18
B6.A-ChrX f 8.54 1.81   8 0.64 0.212 6.26, 10.8 -0.24
B6.A-ChrX m 5.99 1.89   8 0.667 0.315 3.22, 9.04 -0.58
C57BL/6J f 8.81 1.85   16 0.462 0.21 6.17, 12.1 -0.15
C57BL/6J m 7.64 1.38   16 0.346 0.181 4.33, 9.21 -0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 6.3687 0.7217 7.7884 4.9491
A/J m 3.9356 0.7217 5.3552 2.516
B6.A-Chr1 f 9.5088 1.0207 11.5164 7.5011
B6.A-Chr1 m 7.5 1.0207 9.5076 5.4924
B6.A-Chr10 f 9.5563 1.0207 11.5639 7.5486
B6.A-Chr10 m 6.3975 1.0207 8.4051 4.3899
B6.A-Chr11 f 7.52 1.0207 9.5276 5.5124
B6.A-Chr11 m 7.5388 1.0207 9.5464 5.5311
B6.A-Chr12 f 9.0162 1.0207 11.0239 7.0086
B6.A-Chr12 m 6.6087 1.0207 8.6164 4.6011
B6.A-Chr13 f 14.0 1.0207 16.0076 11.9924
B6.A-Chr13 m 12.4387 1.0207 14.4464 10.4311
B6.A-Chr14 f 8.7363 1.0207 10.7439 6.7286
B6.A-Chr14 m 8.7975 1.0207 10.8051 6.7899
B6.A-Chr15 f 6.5375 1.0207 8.5451 4.5299
B6.A-Chr15 m 6.15 1.0207 8.1576 4.1424
B6.A-Chr16 f 8.3862 1.0207 10.3939 6.3786
B6.A-Chr16 m 6.9212 1.0207 8.9289 4.9136
B6.A-Chr17 f 19.4625 1.0207 21.4701 17.4549
B6.A-Chr17 m 16.95 1.0207 18.9576 14.9424
B6.A-Chr18 f 12.0 1.0207 14.0076 9.9924
B6.A-Chr18 m 9.4312 1.0207 11.4389 7.4236
B6.A-Chr19 f 12.075 1.0207 14.0826 10.0674
B6.A-Chr19 m 10.125 1.0207 12.1326 8.1174
B6.A-Chr2 f 9.8133 0.9623 11.7061 7.9205
B6.A-Chr2 m 7.6838 1.0207 9.6914 5.6761
B6.A-Chr3 f 10.4913 1.0207 12.4989 8.4836
B6.A-Chr3 m 7.2563 1.0207 9.2639 5.2486
B6.A-Chr4 f 9.1487 1.0207 11.1564 7.1411
B6.A-Chr4 m 5.6412 1.0207 7.6489 3.6336
B6.A-Chr5 f 4.23 1.0207 6.2376 2.2224
B6.A-Chr5 m 3.9762 1.0207 5.9839 1.9686
B6.A-Chr6 f 11.925 1.0207 13.9326 9.9174
B6.A-Chr6 m 9.8275 1.0207 11.8351 7.8199
B6.A-Chr7 f 4.6888 1.0207 6.6964 2.6811
B6.A-Chr7 m 4.1825 1.0207 6.1901 2.1749
B6.A-Chr8 f 6.865 1.0207 8.8726 4.8574
B6.A-Chr8 m 6.5663 1.0207 8.5739 4.5586
B6.A-Chr9 f 7.2875 1.0207 9.2951 5.2799
B6.A-Chr9 m 7.1312 1.0207 9.1389 5.1236
B6.A-ChrX f 8.5413 1.0207 10.5489 6.5336
B6.A-ChrX m 5.9863 1.0207 7.9939 3.9786
C57BL/6J f 8.8062 0.7217 10.2259 7.3866
C57BL/6J m 7.6425 0.7217 9.0621 6.2229


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 5.1522 0.5103 6.156 4.1484
B6.A-Chr1 both 8.5044 0.7217 9.924 7.0848
B6.A-Chr10 both 7.9769 0.7217 9.3965 6.5573
B6.A-Chr11 both 7.5294 0.7217 8.949 6.1098
B6.A-Chr12 both 7.8125 0.7217 9.2321 6.3929
B6.A-Chr13 both 13.2194 0.7217 14.639 11.7998
B6.A-Chr14 both 8.7669 0.7217 10.1865 7.3473
B6.A-Chr15 both 6.3437 0.7217 7.7634 4.9241
B6.A-Chr16 both 7.6537 0.7217 9.0734 6.2341
B6.A-Chr17 both 18.2062 0.7217 19.6259 16.7866
B6.A-Chr18 both 10.7156 0.7217 12.1352 9.296
B6.A-Chr19 both 11.1 0.7217 12.5196 9.6804
B6.A-Chr2 both 8.7485 0.7014 10.1282 7.3689
B6.A-Chr3 both 8.8738 0.7217 10.2934 7.4541
B6.A-Chr4 both 7.395 0.7217 8.8146 5.9754
B6.A-Chr5 both 4.1031 0.7217 5.5227 2.6835
B6.A-Chr6 both 10.8762 0.7217 12.2959 9.4566
B6.A-Chr7 both 4.4356 0.7217 5.8552 3.016
B6.A-Chr8 both 6.7156 0.7217 8.1352 5.296
B6.A-Chr9 both 7.2094 0.7217 8.629 5.7898
B6.A-ChrX both 7.2638 0.7217 8.6834 5.8441
C57BL/6J both 8.2244 0.5103 9.2282 7.2206




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA