Project measure / variable:   Threadgill2   APAP_Sulf_50_3

ID, description, units MPD:39620   APAP_Sulf_50_3   serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen   [µg/mL]  3h  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - serum acetaminophen sulfate (APAP-sulfate), 50 mg/mL dose acetaminophen 3h



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means1.63   µg/mL
Median of the strain means1.67   µg/mL
SD of the strain means± 0.374
Coefficient of variation (CV)0.230
Min–max range of strain means1.22   –   2.15   µg/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 2.6051 0.6513 0.4422 0.7765
Residuals 17 25.0371 1.4728


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 2.15 1.97   5 0.881 0.916 0.11, 4.62 1.4
C57BL/6J m 1.32 0.394   3 0.227 0.299 1.06, 1.77 -0.82
DBA/2J m 1.67 1.29   5 0.579 0.774 0.18, 3.35 0.11
LP/J m 1.22 0.603   5 0.27 0.496 0.73, 2.25 -1.09
NZW/LacJ m 1.78 0.59   4 0.295 0.331 1.18, 2.58 0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 2.152 0.5427 3.2971 1.0069
C57BL/6J m 1.3167 0.7007 2.7949 0.0
DBA/2J m 1.672 0.5427 2.8171 0.5269
LP/J m 1.216 0.5427 2.3611 0.0709
NZW/LacJ m 1.78 0.6068 3.0602 0.4998




  GWAS USING LINEAR MIXED MODELS