Project measure / variable:   Gupta1   refluxVUR_index

ID, description, units MPD:39115   refluxVUR_index   vesico-ureteric reflux (VUR) index   [score]  
Data set, strains Gupta1   inbred   8 strains     sex: both     age: postnatal d1
Procedure renal function assay
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  STRAIN COMPARISON PLOT
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Gupta1 - vesico-ureteric reflux (VUR) index



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means0.812   score 1.16   score
Median of the strain means0.500   score 0.448   score
SD of the strain means± 0.971 ± 1.35
Coefficient of variation (CV)1.20 1.16
Min–max range of strain means0   –   2.60   score 0   –   3.40   score
Mean sample size per strain7.9   mice 10.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1187 0.1187 0.0957 0.7577
strain 6 54.653 9.1088 7.3404 < 0.0001
sex:strain 6 3.1854 0.5309 0.4278 0.859
Residuals 108 134.0183 1.2409


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0 0.0   10 0.0 0.0 -0.84
129S1/SvImJ m 0.429 1.13   7 0.429 2.65 -0.54
AKR/J f 1.0 1.41   4 0.707 1.41 0.19
AKR/J m 0.467 1.06   15 0.274 2.27 -0.51
C3H/HeJ m 3.4 1.8   15 0.466 0.531 1.66
CBA/J f 1.5 1.73   4 0.866 1.15 0.71
CBA/J m 1.56 1.94   9 0.648 1.25 0.3
DBA/2J f 2.6 2.51   5 1.12 0.965 1.84
DBA/2J m 3.0 0.0   2   0.0 0.0 3.0, 3.0 1.36
FVB/NJ f 0.5 1.15   18 0.271 2.3 -0.32
FVB/NJ m 0.15 0.671   20 0.15 4.47 -0.75
SJL/J f 0.0 0.0   2   0.0 0.0 -0.84
SJL/J m 0.0 0.0   3 0.0 0.0 -0.86
SM/J f 0.0833 0.289   12 0.0833 3.46 -0.75
SM/J m 0.273 0.905   11 0.273 3.32 -0.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0 0.3523 0.6983 -0.6983
129S1/SvImJ m 0.4286 0.421 1.2631 -0.406
AKR/J f 1.0 0.557 2.104 -0.104
AKR/J m 0.4667 0.2876 1.0368 -0.1035
CBA/J f 1.5 0.557 2.604 0.396
CBA/J m 1.5556 0.3713 2.2916 0.8195
DBA/2J f 2.6 0.4982 3.5875 1.6125
DBA/2J m 3.0 0.7877 4.5613 1.4387
FVB/NJ f 0.5 0.2626 1.0204 -0.0204
FVB/NJ m 0.15 0.2491 0.6437 -0.3437
SJL/J f 0.0 0.7877 1.5613 -1.5613
SJL/J m 0.0 0.6431 1.2748 -1.2748
SM/J f 0.0833 0.3216 0.7207 -0.5541
SM/J m 0.2727 0.3359 0.9385 -0.393


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2143 0.2745 0.7584 -0.3298
AKR/J both 0.7333 0.3134 1.3546 0.1121
CBA/J both 1.5278 0.3347 2.1912 0.8643
DBA/2J both 2.8 0.466 3.7237 1.8763
FVB/NJ both 0.325 0.181 0.6837 -0.0337
SJL/J both 0.0 0.5085 1.0078 -1.0078
SM/J both 0.178 0.2325 0.6389 -0.2828




  GWAS USING LINEAR MIXED MODELS