Project measure / variable:   Xing2   gait_score_M12

ID, description, units MPD:36305   gait_score_M12   gait score (1-3)   [score]  at age 12mo  
Data set, strains Xing2   inbred   31 strains     sex: both     age: 52wks
Procedure gait analysis
Ontology mappings

  STRAIN COMPARISON PLOT
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Xing2 - gait score (1-3) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains31 strains
Mean of the strain means2.75   score 2.67   score
Median of the strain means3.00   score 2.78   score
SD of the strain means± 0.464 ± 0.520
Coefficient of variation (CV)0.168 0.195
Min–max range of strain means1.00   –   3.00   score 1.00   –   3.00   score
Mean sample size per strain6.8   mice 6.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3151 0.3151 1.4702 0.2262
strain 27 24.7059 0.915 4.2692 < 0.0001
sex:strain 27 11.4256 0.4232 1.9744 0.0033
Residuals 328 70.3008 0.2143


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.5 0.837   6 0.342 0.335 1.0, 3.0 -0.55
129S1/SvImJ m 2.62 0.518   8 0.183 0.197 2.0, 3.0 -0.09
A/J f 1.67 0.816   6 0.333 0.49 1.0, 3.0 -2.34
A/J m 2.67 0.577   3 0.333 0.217 2.0, 3.0 0.01
AKR/J f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -3.78
AKR/J m 1.14 0.378   7 0.143 0.331 1.0, 2.0 -2.94
BALB/cByJ f 2.88 0.354   8 0.125 0.123 2.0, 3.0 0.27
BALB/cByJ m 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.64
BTBR T+ Itpr3tf/J f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.53
BTBR T+ Itpr3tf/J m 2.88 0.354   8 0.125 0.123 2.0, 3.0 0.41
BUB/BnJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -3.21
C3H/HeJ f 2.75 0.463   8 0.164 0.168 2.0, 3.0 -0.01
C3H/HeJ m 2.62 0.744   8 0.263 0.283 1.0, 3.0 -0.09
C57BL/10J f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.53
C57BL/10J m 2.75 0.707   8 0.25 0.257 1.0, 3.0 0.16
C57BL/6J m 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.64
C57BLKS/J f 2.67 0.516   6 0.211 0.194 2.0, 3.0 -0.18
C57BLKS/J m 1.57 0.787   7 0.297 0.501 1.0, 3.0 -2.11
C57BR/cdJ f 2.12 0.835   8 0.295 0.393 1.0, 3.0 -1.37
C57BR/cdJ m 2.62 0.744   8 0.263 0.283 1.0, 3.0 -0.09
C57L/J f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.53
C57L/J m 2.75 0.707   8 0.25 0.257 1.0, 3.0 0.16
CAST/EiJ f 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.53
CAST/EiJ m 2.86 0.378   7 0.143 0.132 2.0, 3.0 0.37
CBA/J f 2.83 0.408   6 0.167 0.144 2.0, 3.0 0.17
CBA/J m 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.64
DBA/2J f 2.83 0.408   6 0.167 0.144 2.0, 3.0 0.17
DBA/2J m 2.33 1.03   6 0.422 0.443 1.0, 3.0 -0.65
FVB/NJ f 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.53
FVB/NJ m 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.64
KK/HlJ f 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.53
KK/HlJ m 3.0 0.0   9 0.0 0.0 3.0, 3.0 0.64
LP/J f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.53
LP/J m 2.75 0.707   8 0.25 0.257 1.0, 3.0 0.16
MOLF/EiJ f 3.0 0.0   9 0.0 0.0 3.0, 3.0 0.53
MOLF/EiJ m 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.64
MRL/MpJ f 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.53
MRL/MpJ m 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.64
NOD.B10Sn-H2b/J f 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.53
NOD.B10Sn-H2b/J m 3.0 0.0   4 0.0 0.0 3.0, 3.0 0.64
NZO/HlLtJ f 3.0 0.0   5 0.0 0.0 3.0, 3.0 0.53
NZO/HlLtJ m 2.4 0.894   5 0.4 0.373 1.0, 3.0 -0.51
NZW/LacJ f 2.71 0.488   7 0.184 0.18 2.0, 3.0 -0.09
NZW/LacJ m 2.75 0.463   8 0.164 0.168 2.0, 3.0 0.16
P/J f 2.29 0.756   7 0.286 0.331 1.0, 3.0 -1.0
P/J m 3.0 0.0   5 0.0 0.0 3.0, 3.0 0.64
PL/J f 3.0 0.0   4 0.0 0.0 3.0, 3.0 0.53
PL/J m 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.64
PWD/PhJ f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.53
PWD/PhJ m 2.67 0.516   6 0.211 0.194 2.0, 3.0 0.01
RIIIS/J f 3.0 0.0   6 0.0 0.0 3.0, 3.0 0.53
RIIIS/J m 2.78 0.667   9 0.222 0.24 1.0, 3.0 0.22
SJL/J f 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.53
SJL/J m 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.64
SM/J f 2.6 0.548   5 0.245 0.211 2.0, 3.0 -0.33
SM/J m 2.5 0.926   8 0.327 0.37 1.0, 3.0 -0.32
SWR/J f 3.0 0.0   8 0.0 0.0 3.0, 3.0 0.53
SWR/J m 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.64
WSB/EiJ f 3.0 0.0   7 0.0 0.0 3.0, 3.0 0.53
WSB/EiJ m 3.0 0.0   2   0.0 0.0 3.0, 3.0 0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.5 0.189 2.8718 2.1282
129S1/SvImJ m 2.625 0.1637 2.947 2.303
A/J f 1.6667 0.189 2.0385 1.2949
A/J m 2.6667 0.2673 3.1925 2.1408
BALB/cByJ f 2.875 0.1637 3.197 2.553
BALB/cByJ m 3.0 0.1637 3.322 2.678
BTBR T+ Itpr3tf/J f 3.0 0.1637 3.322 2.678
BTBR T+ Itpr3tf/J m 2.875 0.1637 3.197 2.553
C3H/HeJ f 2.75 0.1637 3.072 2.428
C3H/HeJ m 2.625 0.1637 2.947 2.303
C57BL/10J f 3.0 0.1637 3.322 2.678
C57BL/10J m 2.75 0.1637 3.072 2.428
C57BLKS/J f 2.6667 0.189 3.0385 2.2949
C57BLKS/J m 1.5714 0.175 1.9157 1.2272
C57BR/cdJ f 2.125 0.1637 2.447 1.803
C57BR/cdJ m 2.625 0.1637 2.947 2.303
C57L/J f 3.0 0.1637 3.322 2.678
C57L/J m 2.75 0.1637 3.072 2.428
CAST/EiJ f 3.0 0.175 3.3442 2.6558
CAST/EiJ m 2.8571 0.175 3.2014 2.5129
CBA/J f 2.8333 0.189 3.2051 2.4615
CBA/J m 3.0 0.175 3.3442 2.6558
DBA/2J f 2.8333 0.189 3.2051 2.4615
DBA/2J m 2.3333 0.189 2.7051 1.9615
FVB/NJ f 3.0 0.189 3.3718 2.6282
FVB/NJ m 3.0 0.1637 3.322 2.678
KK/HlJ f 3.0 0.175 3.3442 2.6558
KK/HlJ m 3.0 0.1543 3.3036 2.6964
LP/J f 3.0 0.1637 3.322 2.678
LP/J m 2.75 0.1637 3.072 2.428
MOLF/EiJ f 3.0 0.1543 3.3036 2.6964
MOLF/EiJ m 3.0 0.189 3.3718 2.6282
MRL/MpJ f 3.0 0.175 3.3442 2.6558
MRL/MpJ m 3.0 0.1637 3.322 2.678
NOD.B10Sn-H2b/J f 3.0 0.189 3.3718 2.6282
NOD.B10Sn-H2b/J m 3.0 0.2315 3.4554 2.5446
NZO/HlLtJ f 3.0 0.207 3.4073 2.5927
NZO/HlLtJ m 2.4 0.207 2.8073 1.9927
NZW/LacJ f 2.7143 0.175 3.0585 2.3701
NZW/LacJ m 2.75 0.1637 3.072 2.428
P/J f 2.2857 0.175 2.6299 1.9415
P/J m 3.0 0.207 3.4073 2.5927
PL/J f 3.0 0.2315 3.4554 2.5446
PL/J m 3.0 0.189 3.3718 2.6282
PWD/PhJ f 3.0 0.1637 3.322 2.678
PWD/PhJ m 2.6667 0.189 3.0385 2.2949
RIIIS/J f 3.0 0.189 3.3718 2.6282
RIIIS/J m 2.7778 0.1543 3.0814 2.4742
SJL/J f 3.0 0.175 3.3442 2.6558
SJL/J m 3.0 0.175 3.3442 2.6558
SM/J f 2.6 0.207 3.0073 2.1927
SM/J m 2.5 0.1637 2.822 2.178
SWR/J f 3.0 0.1637 3.322 2.678
SWR/J m 3.0 0.175 3.3442 2.6558
WSB/EiJ f 3.0 0.175 3.3442 2.6558
WSB/EiJ m 3.0 0.3274 3.644 2.356


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.5625 0.125 2.8084 2.3166
A/J both 2.1667 0.1637 2.4887 1.8447
BALB/cByJ both 2.9375 0.1157 3.1652 2.7098
BTBR T+ Itpr3tf/J both 2.9375 0.1157 3.1652 2.7098
C3H/HeJ both 2.6875 0.1157 2.9152 2.4598
C57BL/10J both 2.875 0.1157 3.1027 2.6473
C57BLKS/J both 2.119 0.1288 2.3724 1.8657
C57BR/cdJ both 2.375 0.1157 2.6027 2.1473
C57L/J both 2.875 0.1157 3.1027 2.6473
CAST/EiJ both 2.9286 0.1237 3.172 2.6852
CBA/J both 2.9167 0.1288 3.17 2.6633
DBA/2J both 2.5833 0.1336 2.8462 2.3204
FVB/NJ both 3.0 0.125 3.2459 2.7541
KK/HlJ both 3.0 0.1167 3.2295 2.7705
LP/J both 2.875 0.1157 3.1027 2.6473
MOLF/EiJ both 3.0 0.122 3.24 2.76
MRL/MpJ both 3.0 0.1198 3.2357 2.7643
NOD.B10Sn-H2b/J both 3.0 0.1494 3.2939 2.7061
NZO/HlLtJ both 2.7 0.1464 2.988 2.412
NZW/LacJ both 2.7321 0.1198 2.9678 2.4965
P/J both 2.6429 0.1355 2.9095 2.3762
PL/J both 3.0 0.1494 3.2939 2.7061
PWD/PhJ both 2.8333 0.125 3.0793 2.5874
RIIIS/J both 2.8889 0.122 3.1289 2.6489
SJL/J both 3.0 0.1237 3.2434 2.7566
SM/J both 2.55 0.132 2.8096 2.2904
SWR/J both 3.0 0.1198 3.2357 2.7643
WSB/EiJ both 3.0 0.1856 3.3651 2.6349




  GWAS USING LINEAR MIXED MODELS