Project measure / variable:   Korstanje1   CREA_M12


  STRAIN COMPARISON PLOT
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Korstanje1 - creatinine (urine CREA) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means75.9   mg/dL 81.8   mg/dL
Median of the strain means74.8   mg/dL 78.8   mg/dL
SD of the strain means± 20.7 ± 23.3
Coefficient of variation (CV)0.273 0.284
Min–max range of strain means30.3   –   108   mg/dL 42.1   –   138   mg/dL
Mean sample size per strain7.5   mice 7.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4633.6731 4633.6731 11.6038 0.0007
strain 29 165750.1659 5715.523 14.313 < 0.0001
sex:strain 29 51178.0636 1764.7608 4.4194 < 0.0001
Residuals 388 154937.3081 399.323


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 93.0 18.8   8 6.66 0.202 70.8, 118.0 0.82
129S1/SvImJ m 72.2 20.5   8 7.25 0.284 32.0, 101.0 -0.41
A/J f 81.1 9.58   8 3.39 0.118 68.9, 95.4 0.25
A/J m 122.0 20.1   8 7.11 0.165 87.3, 142.0 1.73
BALB/cByJ f 86.9 22.1   8 7.83 0.255 65.7, 116.0 0.53
BALB/cByJ m 101.0 24.0   8 8.49 0.237 64.7, 145.0 0.82
BTBR T+ Itpr3tf/J f 58.7 14.0   8 4.94 0.238 32.2, 74.0 -0.83
BTBR T+ Itpr3tf/J m 62.6 10.9   8 3.84 0.173 44.6, 77.7 -0.83
BUB/BnJ f 59.4 19.1   8 6.76 0.322 40.2, 97.4 -0.8
BUB/BnJ m 82.5 28.7   6 11.7 0.348 34.4, 112.0 0.03
C3H/HeJ f 75.9 15.0   8 5.32 0.198 50.7, 90.6 0.0
C3H/HeJ m 94.3 6.49   8 2.29 0.0688 87.4, 107.0 0.54
C57BL/10J f 108.0 26.9   8 9.53 0.249 67.2, 146.0 1.55
C57BL/10J m 130.0 3.37   8 1.19 0.0259 127.0, 135.0 2.07
C57BL/6J f 67.0 13.3   8 4.71 0.199 52.8, 86.8 -0.43
C57BL/6J m 46.7 15.4   8 5.45 0.33 28.9, 68.5 -1.51
C57BLKS/J f 82.0 19.9   7 7.51 0.243 45.7, 104.0 0.29
C57BLKS/J m 70.2 13.2   7 4.98 0.188 58.6, 92.3 -0.5
C57BR/cdJ f 70.6 14.3   7 5.41 0.203 47.2, 93.3 -0.26
C57BR/cdJ m 57.2 11.7   8 4.13 0.204 44.9, 71.7 -1.06
C57L/J f 62.2 25.0   8 8.84 0.402 38.4, 119.0 -0.66
C57L/J m 87.4 13.0   8 4.6 0.149 72.1, 114.0 0.24
CAST/EiJ f 83.0 12.8   7 4.85 0.155 70.0, 107.0 0.34
CAST/EiJ m 78.4 12.9   7 4.87 0.164 66.1, 102.0 -0.15
CBA/J f 98.2 8.52   7 3.22 0.0868 90.6, 116.0 1.08
CBA/J m 97.5 8.96   7 3.39 0.0919 86.7, 107.0 0.67
DBA/2J f 73.8 26.1   6 10.6 0.353 37.2, 105.0 -0.1
DBA/2J m 81.7 14.7   5 6.57 0.18 67.1, 98.9 -0.01
FVB/NJ f 100.0 14.7   7 5.55 0.147 91.5, 133.0 1.16
FVB/NJ m 138.0 44.2   8 15.6 0.32 66.5, 206.0 2.41
KK/HlJ f 73.8 17.7   7 6.68 0.24 52.9, 94.8 -0.1
KK/HlJ m 95.1 23.0   8 8.12 0.241 47.4, 117.0 0.57
LP/J f 97.8 39.5   8 14.0 0.404 66.0, 177.0 1.06
LP/J m 74.6 15.0   8 5.29 0.2 55.4, 95.0 -0.31
MRL/MpJ f 97.9 32.7   7 12.4 0.335 62.8, 140.0 1.06
MRL/MpJ m 72.3 21.7   8 7.68 0.3 53.9, 121.0 -0.41
NOD.B10Sn-H2b/J f 65.2 15.7   7 5.93 0.241 45.6, 89.7 -0.52
NOD.B10Sn-H2b/J m 77.8 23.0   10 7.28 0.296 41.5, 113.0 -0.17
NON/ShiLtJ f 107.0 26.5   8 9.38 0.247 64.6, 151.0 1.5
NON/ShiLtJ m 88.6 20.1   8 7.09 0.226 64.4, 115.0 0.29
NZO/HlLtJ f 50.3 12.4   7 4.7 0.247 35.7, 71.2 -1.24
NZO/HlLtJ m 52.7 15.7   6 6.43 0.299 33.2, 73.6 -1.25
NZW/LacJ f 37.2 21.1   8 7.48 0.568 18.0, 69.5 -1.87
NZW/LacJ m 74.7 14.6   8 5.15 0.195 54.4, 97.2 -0.31
P/J f 58.1 34.0   7 12.9 0.586 28.8, 114.0 -0.86
P/J m 70.5 21.2   4 10.6 0.3 53.3, 97.1 -0.49
PL/J f 60.2 14.8   7 5.58 0.245 46.0, 90.3 -0.76
PL/J m 97.4 8.24   6 3.36 0.0846 87.5, 109.0 0.67
PWD/PhJ f 47.0 17.8   8 6.3 0.379 17.3, 64.3 -1.4
PWD/PhJ m 79.3 29.2   8 10.3 0.369 55.7, 136.0 -0.11
RIIIS/J f 94.9 22.1   8 7.81 0.233 73.4, 142.0 0.92
RIIIS/J m 86.9 25.7   8 9.09 0.296 42.6, 110.0 0.22
SJL/J f 70.4 29.0   5 13.0 0.412 44.8, 120.0 -0.27
SJL/J m 65.9 22.7   8 8.02 0.344 34.4, 102.0 -0.69
SM/J f 84.0 4.4   8 1.56 0.0524 75.9, 91.1 0.39
SM/J m 47.9 16.1   9 5.36 0.335 20.3, 68.2 -1.46
SWR/J f 30.3 11.8   8 4.16 0.389 15.9, 52.4 -2.2
SWR/J m 42.1 3.08   6 1.26 0.0731 37.5, 46.5 -1.71
WSB/EiJ f 104.0 13.3   7 5.02 0.127 83.1, 124.0 1.36
WSB/EiJ m 108.0 8.54   8 3.02 0.0788 89.4, 114.0 1.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 93.05 7.0651 106.9406 79.1594
129S1/SvImJ m 72.2375 7.0651 86.1281 58.3469
A/J f 81.075 7.0651 94.9656 67.1844
A/J m 121.7875 7.0651 135.6781 107.8969
BALB/cByJ f 86.8875 7.0651 100.7781 72.9969
BALB/cByJ m 101.4375 7.0651 115.3281 87.5469
BTBR T+ Itpr3tf/J f 58.75 7.0651 72.6406 44.8594
BTBR T+ Itpr3tf/J m 62.65 7.0651 76.5406 48.7594
BUB/BnJ f 59.4 7.0651 73.2906 45.5094
BUB/BnJ m 82.5 8.1581 98.5395 66.4605
C3H/HeJ f 75.875 7.0651 89.7656 61.9844
C3H/HeJ m 94.3375 7.0651 108.2281 80.4469
C57BL/10J f 108.4125 7.0651 122.3031 94.5219
C57BL/10J m 130.25 7.0651 144.1406 116.3594
C57BL/6J f 67.025 7.0651 80.9156 53.1344
C57BL/6J m 46.65 7.0651 60.5406 32.7594
C57BLKS/J f 81.9571 7.5529 96.8069 67.1074
C57BLKS/J m 70.1714 7.5529 85.0211 55.3217
C57BR/cdJ f 70.5714 7.5529 85.4211 55.7217
C57BR/cdJ m 57.175 7.0651 71.0656 43.2844
C57L/J f 62.2 7.0651 76.0906 48.3094
C57L/J m 87.3625 7.0651 101.2531 73.4719
CAST/EiJ f 83.0429 7.5529 97.8926 68.1931
CAST/EiJ m 78.4 7.5529 93.2497 63.5503
CBA/J f 98.2429 7.5529 113.0926 83.3931
CBA/J m 97.4857 7.5529 112.3354 82.636
DBA/2J f 73.85 8.1581 89.8895 57.8105
DBA/2J m 81.68 8.9367 99.2504 64.1096
FVB/NJ f 100.1 7.5529 114.9497 85.2503
FVB/NJ m 138.0 7.0651 151.8906 124.1094
KK/HlJ f 73.7857 7.5529 88.6354 58.936
KK/HlJ m 95.125 7.0651 109.0156 81.2344
LP/J f 97.775 7.0651 111.6656 83.8844
LP/J m 74.575 7.0651 88.4656 60.6844
MRL/MpJ f 97.8857 7.5529 112.7354 83.036
MRL/MpJ m 72.275 7.0651 86.1656 58.3844
NOD.B10Sn-H2b/J f 65.2429 7.5529 80.0926 50.3931
NOD.B10Sn-H2b/J m 77.78 6.3192 90.2042 65.3558
NON/ShiLtJ f 107.325 7.0651 121.2156 93.4344
NON/ShiLtJ m 88.5875 7.0651 102.4781 74.6969
NZO/HlLtJ f 50.3143 7.5529 65.164 35.4646
NZO/HlLtJ m 52.7333 8.1581 68.7729 36.6938
NZW/LacJ f 37.2 7.0651 51.0906 23.3094
NZW/LacJ m 74.7 7.0651 88.5906 60.8094
P/J f 58.1143 7.5529 72.964 43.2646
P/J m 70.525 9.9915 90.1693 50.8807
PL/J f 60.1857 7.5529 75.0354 45.336
PL/J m 97.4167 8.1581 113.4562 81.3771
PWD/PhJ f 47.0375 7.0651 60.9281 33.1469
PWD/PhJ m 79.2625 7.0651 93.1531 65.3719
RIIIS/J f 94.95 7.0651 108.8406 81.0594
RIIIS/J m 86.875 7.0651 100.7656 72.9844
SJL/J f 70.36 8.9367 87.9304 52.7896
SJL/J m 65.8875 7.0651 79.7781 51.9969
SM/J f 84.05 7.0651 97.9406 70.1594
SM/J m 47.9444 6.661 61.0407 34.8482
SWR/J f 30.2625 7.0651 44.1531 16.3719
SWR/J m 42.1 8.1581 58.1395 26.0605
WSB/EiJ f 104.4571 7.5529 119.3069 89.6074
WSB/EiJ m 108.425 7.0651 122.3156 94.5344


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 82.6438 4.9958 92.4659 72.8216
A/J both 101.4312 4.9958 111.2534 91.6091
BALB/cByJ both 94.1625 4.9958 103.9847 84.3403
BTBR T+ Itpr3tf/J both 60.7 4.9958 70.5222 50.8778
BUB/BnJ both 70.95 5.396 81.5591 60.3409
C3H/HeJ both 85.1062 4.9958 94.9284 75.2841
C57BL/10J both 119.3313 4.9958 129.1534 109.5091
C57BL/6J both 56.8375 4.9958 66.6597 47.0153
C57BLKS/J both 76.0643 5.3407 86.5646 65.564
C57BR/cdJ both 63.8732 5.1711 74.0401 53.7063
C57L/J both 74.7813 4.9958 84.6034 64.9591
CAST/EiJ both 80.7214 5.3407 91.2218 70.2211
CBA/J both 97.8643 5.3407 108.3646 87.364
DBA/2J both 77.765 6.0502 89.6602 65.8698
FVB/NJ both 119.05 5.1711 129.2169 108.8831
KK/HlJ both 84.4554 5.1711 94.6223 74.2885
LP/J both 86.175 4.9958 95.9972 76.3528
MRL/MpJ both 85.0804 5.1711 95.2473 74.9135
NOD.B10Sn-H2b/J both 71.5114 4.9239 81.1923 61.8306
NON/ShiLtJ both 97.9562 4.9958 107.7784 88.1341
NZO/HlLtJ both 51.5238 5.5588 62.4529 40.5947
NZW/LacJ both 55.95 4.9958 65.7722 46.1278
P/J both 64.3196 6.2625 76.6324 52.0069
PL/J both 78.8012 5.5588 89.7303 67.8721
PWD/PhJ both 63.15 4.9958 72.9722 53.3278
RIIIS/J both 90.9125 4.9958 100.7347 81.0903
SJL/J both 68.1237 5.6961 79.3227 56.9248
SM/J both 65.9972 4.855 75.5426 56.4518
SWR/J both 36.1812 5.396 46.7904 25.5721
WSB/EiJ both 106.4411 5.1711 116.608 96.2742




  GWAS USING LINEAR MIXED MODELS