Project measure / variable:   Eumorphia2   BMD_12wk

ID, description, units MPD:25904   BMD_12wk   bone mineral density (BMD)   [g/cm2]  at age 12wks  
Data set, strains Eumorphia2   inbred   5 strains     sex: both
Procedure DXA
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  STRAIN COMPARISON PLOT
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Eumorphia2 - bone mineral density (BMD) at age 12wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested5 strains5 strains
Mean of the strain means0.0552   g/cm2 0.0557   g/cm2
Median of the strain means0.0576   g/cm2 0.0565   g/cm2
SD of the strain means± 0.00438 ± 0.00485
Coefficient of variation (CV)0.0794 0.0870
Min–max range of strain means0.0487   –   0.0593   g/cm2 0.0506   –   0.0629   g/cm2
Mean sample size per strain11.0   mice 10.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0 0.0 2.3131 0.1315
strain 4 0.0019 0.0005 48.3688 < 0.0001
sex:strain 4 0.0001 0.0 3.0143 0.0216
Residuals 99 0.001 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S2/SvPas f 0.0577 0.00241   10 0.000761 0.0417 0.0538, 0.062 0.57
129S2/SvPas m 0.0565 0.0021   10 0.000663 0.0371 0.053, 0.059 0.16
BALB/cJ f 0.0528 0.00223   10 0.000706 0.0423 0.0471, 0.0549 -0.55
BALB/cJ m 0.0519 0.0018   10 0.00057 0.0347 0.0493, 0.0541 -0.79
C3HeB/FeJ f 0.0576 0.00142   10 0.000448 0.0246 0.0555, 0.0605 0.54
C3HeB/FeJ m 0.0567 0.00156   10 0.000493 0.0275 0.0548, 0.0596 0.2
C57BL/6J f 0.0487 0.00214   10 0.000678 0.044 0.0454, 0.0539 -1.49
C57BL/6J m 0.0506 0.00136   9 0.000453 0.0269 0.0483, 0.0526 -1.06
C57BL/6N f 0.0593 0.00595   15 0.00154 0.1 0.05, 0.072 0.93
C57BL/6N m 0.0629 0.00377   15 0.000973 0.0599 0.057, 0.072 1.48


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas f 0.0577 0.001 0.0596 0.0557
129S2/SvPas m 0.0565 0.001 0.0584 0.0546
BALB/cJ f 0.0528 0.001 0.0547 0.0508
BALB/cJ m 0.0519 0.001 0.0539 0.05
C3HeB/FeJ f 0.0576 0.001 0.0596 0.0557
C3HeB/FeJ m 0.0567 0.001 0.0586 0.0547
C57BL/6J f 0.0487 0.001 0.0507 0.0468
C57BL/6J m 0.0506 0.001 0.0527 0.0486
C57BL/6N f 0.0593 0.0008 0.0609 0.0577
C57BL/6N m 0.0629 0.0008 0.0645 0.0613


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S2/SvPas both 0.0571 0.0007 0.0585 0.0557
BALB/cJ both 0.0524 0.0007 0.0537 0.051
C3HeB/FeJ both 0.0572 0.0007 0.0585 0.0558
C57BL/6J both 0.0497 0.0007 0.0511 0.0482
C57BL/6N both 0.0611 0.0006 0.0622 0.06




GWAS analysis not available: SNP data is not available for enough strains (at least 4)