Project measure / variable:   Yuan3   CO2_M06

ID, description, units MPD:24461   CO2_M06   dissolved-ionized carbon dioxide (CO2)   [mmol/L]  at age 6mo  
Data set, strains Yuan3   inbred   30 strains     sex: both     age: 26wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - dissolved-ionized carbon dioxide (CO2) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested28 strains25 strains
Mean of the strain means16.0   mmol/L 16.5   mmol/L
Median of the strain means16.2   mmol/L 17.0   mmol/L
SD of the strain means± 1.65 ± 2.93
Coefficient of variation (CV)0.103 0.177
Min–max range of strain means13.1   –   20.4   mmol/L 7.83   –   20.7   mmol/L
Mean sample size per strain7.9   mice 7.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15.4131 15.4131 2.4634 0.1175
strain 22 1396.9309 63.4969 10.1485 < 0.0001
sex:strain 22 638.4222 29.0192 4.6381 < 0.0001
Residuals 315 1970.8763 6.2568


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 17.7 1.93   6 0.788 0.109 15.6, 20.0 1.03
129S1/SvImJ m 19.9 3.29   8 1.16 0.165 15.6, 25.0 1.15
A/J f 15.3 2.88   16 0.721 0.188 8.4, 20.4 -0.43
A/J m 12.3 3.16   8 1.12 0.257 7.4, 17.0 -1.45
BALB/cByJ f 14.2 2.54   8 0.897 0.178 10.8, 18.4 -1.1
BALB/cByJ m 17.6 1.51   8 0.533 0.0857 15.4, 20.2 0.36
BTBR T+ Itpr3tf/J f 17.1 1.55   4 0.777 0.0908 15.2, 19.0 0.66
BTBR T+ Itpr3tf/J m 16.6 2.52   8 0.889 0.151 12.8, 21.4 0.02
BUB/BnJ f 16.9 1.84   6 0.751 0.109 14.4, 18.8 0.54
BUB/BnJ m 15.9 1.13   6 0.461 0.0709 14.6, 17.6 -0.22
C3H/HeJ f 20.4 2.33   8 0.824 0.114 18.0, 25.0 2.67
C3H/HeJ m 17.5 2.39   7 0.903 0.137 12.8, 19.6 0.33
C57BL/10J f 14.3 2.32   8 0.82 0.162 11.8, 18.6 -1.04
C57BL/10J m 14.9 3.03   8 1.07 0.203 11.4, 20.0 -0.56
C57BL/6J f 15.3 1.93   8 0.683 0.126 12.5, 18.9 -0.43
C57BL/6J m 16.5 0.755   4 0.377 0.0459 15.6, 17.4 -0.01
C57BLKS/J f 18.7 1.59   8 0.562 0.0851 15.8, 21.0 1.63
C57BLKS/J m 20.7 2.09   8 0.74 0.101 18.2, 24.8 1.42
C57BR/cdJ m 19.1 2.64   4 1.32 0.138 15.6, 21.8 0.88
C57L/J f 17.2 2.34   8 0.827 0.136 13.4, 20.0 0.72
C57L/J m 18.1 1.68   8 0.594 0.0925 15.2, 20.6 0.53
CAST/EiJ f 16.6 1.98   4 0.988 0.119 15.1, 19.5 0.36
CBA/J f 17.2 1.89   8 0.667 0.11 13.8, 20.0 0.72
DBA/2J f 15.0 3.51   8 1.24 0.234 8.6, 20.6 -0.61
DBA/2J m 12.2 3.35   16 0.838 0.275 8.4, 18.0 -1.48
FVB/NJ f 13.9 2.24   14 0.598 0.161 10.2, 17.6 -1.28
FVB/NJ m 16.0 1.56   9 0.519 0.0972 13.6, 18.8 -0.18
KK/HlJ f 16.3 2.76   8 0.976 0.169 11.0, 19.8 0.18
LP/J f 16.8 1.97   8 0.695 0.117 14.1, 20.1 0.48
LP/J m 17.6 2.41   8 0.853 0.137 13.0, 21.2 0.36
MOLF/EiJ f 17.0 0.0   2   0.0 0.0 17.0, 17.0 0.6
MOLF/EiJ m 12.6 1.67   5 0.748 0.133 11.0, 15.0 -1.34
MRL/MpJ m 20.1 3.34   8 1.18 0.167 13.0, 22.6 1.22
NOD.B10Sn-H2b/J f 17.6 1.45   9 0.484 0.0826 15.0, 20.3 0.97
NOD.B10Sn-H2b/J m 19.6 1.03   7 0.39 0.0527 17.5, 20.7 1.05
NON/ShiLtJ f 14.4 1.63   8 0.577 0.114 11.2, 16.0 -0.98
NON/ShiLtJ m 7.83 3.04   7 1.15 0.389 3.8, 12.6 -2.97
NZO/HlLtJ f 16.0 1.8   8 0.636 0.112 13.0, 18.6 0.0
NZO/HlLtJ m 15.3 6.09   6 2.49 0.398 8.6, 24.8 -0.42
NZW/LacJ f 16.7 1.96   8 0.692 0.117 12.8, 19.2 0.42
P/J f 13.1 2.5   8 0.882 0.191 11.0, 18.0 -1.76
P/J m 19.0 1.78   8 0.628 0.0937 16.3, 21.3 0.84
PL/J f 15.3 4.29   11 1.29 0.28 9.2, 19.8 -0.43
PL/J m 17.6 1.25   8 0.44 0.071 16.0, 19.4 0.36
PWD/PhJ f 14.0 2.12   8 0.751 0.151 11.0, 16.0 -1.22
PWD/PhJ m 15.5 2.21   7 0.833 0.142 11.4, 18.0 -0.35
RIIIS/J f 16.2 3.89   7 1.47 0.24 10.6, 21.2 0.12
RIIIS/J m 16.3 2.09   8 0.738 0.128 12.2, 18.4 -0.08
SJL/J f 14.9 1.73   8 0.61 0.115 12.8, 18.4 -0.67
SM/J f 16.2 1.67   8 0.592 0.103 13.4, 18.2 0.12
SM/J m 17.7 1.59   6 0.65 0.0898 15.2, 19.4 0.4
WSB/EiJ f 13.9 2.17   8 0.766 0.156 9.9, 16.7 -1.28
WSB/EiJ m 17.0 1.06   6 0.431 0.062 15.5, 18.1 0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 17.6667 1.0212 19.6758 15.6575
129S1/SvImJ m 19.925 0.8844 21.665 18.185
A/J f 15.3 0.6253 16.5304 14.0696
A/J m 12.325 0.8844 14.065 10.585
BALB/cByJ f 14.25 0.8844 15.99 12.51
BALB/cByJ m 17.6 0.8844 19.34 15.86
BTBR T+ Itpr3tf/J f 17.1 1.2507 19.5607 14.6393
BTBR T+ Itpr3tf/J m 16.65 0.8844 18.39 14.91
BUB/BnJ f 16.9 1.0212 18.9092 14.8908
BUB/BnJ m 15.9333 1.0212 17.9425 13.9242
C3H/HeJ f 20.375 0.8844 22.115 18.635
C3H/HeJ m 17.4857 0.9454 19.3459 15.6256
C57BL/10J f 14.3 0.8844 16.04 12.56
C57BL/10J m 14.925 0.8844 16.665 13.185
C57BL/6J f 15.325 0.8844 17.065 13.585
C57BL/6J m 16.45 1.2507 18.9107 13.9893
C57BLKS/J f 18.675 0.8844 20.415 16.935
C57BLKS/J m 20.7 0.8844 22.44 18.96
C57L/J f 17.2 0.8844 18.94 15.46
C57L/J m 18.15 0.8844 19.89 16.41
DBA/2J f 15.025 0.8844 16.765 13.285
DBA/2J m 12.175 0.6253 13.4054 10.9446
FVB/NJ f 13.8857 0.6685 15.201 12.5704
FVB/NJ m 16.0 0.8338 17.6405 14.3595
LP/J f 16.775 0.8844 18.515 15.035
LP/J m 17.65 0.8844 19.39 15.91
MOLF/EiJ f 17.0 1.7687 20.48 13.52
MOLF/EiJ m 12.6 1.1186 14.8009 10.3991
NOD.B10Sn-H2b/J f 17.5889 0.8338 19.2294 15.9484
NOD.B10Sn-H2b/J m 19.5857 0.9454 21.4459 17.7256
NON/ShiLtJ f 14.375 0.8844 16.115 12.635
NON/ShiLtJ m 7.8286 0.9454 9.6887 5.9684
NZO/HlLtJ f 16.0 0.8844 17.74 14.26
NZO/HlLtJ m 15.3 1.0212 17.3092 13.2908
P/J f 13.1 0.8844 14.84 11.36
P/J m 18.95 0.8844 20.69 17.21
PL/J f 15.3091 0.7542 16.793 13.8252
PL/J m 17.55 0.8844 19.29 15.81
PWD/PhJ f 14.025 0.8844 15.765 12.285
PWD/PhJ m 15.5429 0.9454 17.403 13.6827
RIIIS/J f 16.1714 0.9454 18.0316 14.3113
RIIIS/J m 16.3 0.8844 18.04 14.56
SM/J f 16.225 0.8844 17.965 14.485
SM/J m 17.7333 1.0212 19.7425 15.7242
WSB/EiJ f 13.9 0.8844 15.64 12.16
WSB/EiJ m 17.0333 1.0212 19.0425 15.0242


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.7958 0.6754 20.1248 17.4669
A/J both 13.8125 0.5416 14.878 12.747
BALB/cByJ both 15.925 0.6253 17.1554 14.6946
BTBR T+ Itpr3tf/J both 16.875 0.7659 18.3819 15.3681
BUB/BnJ both 16.4167 0.7221 17.8374 14.996
C3H/HeJ both 18.9304 0.6473 20.2039 17.6568
C57BL/10J both 14.6125 0.6253 15.8429 13.3821
C57BL/6J both 15.8875 0.7659 17.3944 14.3806
C57BLKS/J both 19.6875 0.6253 20.9179 18.4571
C57L/J both 17.675 0.6253 18.9054 16.4446
DBA/2J both 13.6 0.5416 14.6655 12.5345
FVB/NJ both 14.9429 0.5343 15.9942 13.8915
LP/J both 17.2125 0.6253 18.4429 15.9821
MOLF/EiJ both 14.8 1.0464 16.8588 12.7412
NOD.B10Sn-H2b/J both 18.5873 0.6303 19.8274 17.3472
NON/ShiLtJ both 11.1018 0.6473 12.3753 9.8282
NZO/HlLtJ both 15.65 0.6754 16.9789 14.3211
P/J both 16.025 0.6253 17.2554 14.7946
PL/J both 16.4295 0.5811 17.5729 15.2861
PWD/PhJ both 14.7839 0.6473 16.0575 13.5104
RIIIS/J both 16.2357 0.6473 17.5093 14.9622
SM/J both 16.9792 0.6754 18.3081 15.6502
WSB/EiJ both 15.4667 0.6754 16.7956 14.1377




  GWAS USING LINEAR MIXED MODELS