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Project measure / variable:   Peters4   MCHC_M24


  STRAIN COMPARISON PLOT
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Peters4 - mean RBC hemoglobin concentration (MCHC) at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains12 strains
Mean of the strain means31.5   g/dL 31.6   g/dL
Median of the strain means31.6   g/dL 32.0   g/dL
SD of the strain means± 1.25 ± 1.33
Coefficient of variation (CV)0.0395 0.0420
Min–max range of strain means29.5   –   33.9   g/dL 28.0   –   33.0   g/dL
Mean sample size per strain6.7   mice 6.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.2122 4.2122 3.7133 0.0564
strain 9 108.9449 12.105 10.6713 < 0.0001
sex:strain 9 69.0342 7.6705 6.762 < 0.0001
Residuals 119 134.9875 1.1343


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 32.3 1.05   8 0.371 0.0325 30.4, 34.0 0.62
129S1/SvImJ m 32.1 0.58   12 0.167 0.0181 31.4, 32.9 0.38
A/J m 31.8 0.424   2   0.3 0.0133 31.5, 32.1 0.16
BALB/cByJ f 33.9 1.65   6 0.673 0.0487 32.3, 36.8 1.91
C57BL/10J f 30.3 1.12   7 0.424 0.037 28.5, 31.7 -0.99
C57BL/10J m 30.7 1.51   8 0.536 0.0493 28.3, 33.6 -0.67
C57BL/6J f 29.5 0.959   6 0.392 0.0325 28.0, 30.4 -1.63
C57BL/6J m 32.1 0.626   7 0.236 0.0195 31.3, 33.0 0.38
C57BLKS/J f 30.3 0.615   6 0.251 0.0203 29.4, 31.2 -0.99
C57BLKS/J m 32.2 0.212   7 0.08 0.00657 31.9, 32.5 0.46
C57BR/cdJ f 31.2 0.711   7 0.269 0.0228 30.3, 32.3 -0.26
C57BR/cdJ m 28.0 2.64   6 1.08 0.0942 25.0, 31.5 -2.71
LP/J f 31.7 0.618   7 0.233 0.0195 31.0, 32.8 0.14
LP/J m 31.6 0.456   5 0.204 0.0144 31.3, 32.4 0.01
NON/ShiLtJ f 31.1 0.9   7 0.34 0.0289 29.9, 32.0 -0.34
NON/ShiLtJ m 31.2 0.455   6 0.186 0.0146 30.5, 31.6 -0.3
NZW/LacJ f 32.7 1.5   7 0.567 0.0459 30.1, 34.7 0.94
NZW/LacJ m 33.0 0.883   7 0.334 0.0268 31.2, 33.8 1.06
PWD/PhJ f 32.2 1.24   6 0.507 0.0385 30.6, 34.0 0.54
PWD/PhJ m 32.9 1.19   6 0.484 0.0361 31.2, 34.2 0.99
SM/J m 31.1 0.818   7 0.309 0.0263 30.0, 32.0 -0.37
WSB/EiJ f 31.6 0.608   7 0.23 0.0193 30.8, 32.4 0.06
WSB/EiJ m 32.4 1.22   7 0.46 0.0375 30.7, 34.4 0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 32.275 0.3766 33.0206 31.5294
129S1/SvImJ m 32.075 0.3075 32.6838 31.4662
C57BL/10J f 30.3 0.4026 31.0971 29.5029
C57BL/10J m 30.7375 0.3766 31.4831 29.9919
C57BL/6J f 29.5 0.4348 30.361 28.639
C57BL/6J m 32.1143 0.4026 32.9114 31.3172
C57BLKS/J f 30.2667 0.4348 31.1276 29.4057
C57BLKS/J m 32.1857 0.4026 32.9828 31.3886
C57BR/cdJ f 31.2429 0.4026 32.04 30.4458
C57BR/cdJ m 28.0167 0.4348 28.8776 27.1557
LP/J f 31.6857 0.4026 32.4828 30.8886
LP/J m 31.64 0.4763 32.5831 30.6969
NON/ShiLtJ f 31.1 0.4026 31.8971 30.3029
NON/ShiLtJ m 31.1667 0.4348 32.0276 30.3057
NZW/LacJ f 32.6571 0.4026 33.4542 31.86
NZW/LacJ m 32.9571 0.4026 33.7542 32.16
PWD/PhJ f 32.25 0.4348 33.111 31.389
PWD/PhJ m 32.85 0.4348 33.711 31.989
WSB/EiJ f 31.5571 0.4026 32.3542 30.76
WSB/EiJ m 32.4 0.4026 33.1971 31.6029


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 32.175 0.2431 32.6563 31.6937
C57BL/10J both 30.5187 0.2756 31.0645 29.973
C57BL/6J both 30.8071 0.2963 31.3938 30.2205
C57BLKS/J both 31.2262 0.2963 31.8128 30.6395
C57BR/cdJ both 29.6298 0.2963 30.2164 29.0431
LP/J both 31.6629 0.3118 32.2803 31.0454
NON/ShiLtJ both 31.1333 0.2963 31.72 30.5467
NZW/LacJ both 32.8071 0.2846 33.3708 32.2435
PWD/PhJ both 32.55 0.3075 33.1588 31.9412
WSB/EiJ both 31.9786 0.2846 32.5422 31.4149




  GWAS USING LINEAR MIXED MODELS