Project measure / variable:   Petkova1   CD8_mem_effector_M06

ID, description, units MPD:24266   CD8_mem_effector_M06   CD8 T cells, effector memory, as percentage of total CD8 T cells   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, effector memory, as percentage of total CD8 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means15.6   % 12.5   %
Median of the strain means8.26   % 7.17   %
SD of the strain means± 14.3 ± 13.5
Coefficient of variation (CV)0.920 1.08
Min–max range of strain means1.32   –   48.3   % 0.920   –   49.1   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 993.1894 993.1894 28.5891 < 0.0001
strain 30 81555.4979 2718.5166 78.2528 < 0.0001
sex:strain 30 12520.7602 417.3587 12.0137 < 0.0001
Residuals 435 15111.9797 34.7402


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.9 7.01   8 2.48 0.335 9.9, 29.7 0.37
129S1/SvImJ m 16.8 2.66   8 0.939 0.158 13.7, 21.8 0.32
A/J f 48.3 8.46   8 2.99 0.175 36.8, 65.4 2.28
A/J m 41.8 5.98   8 2.12 0.143 31.0, 48.2 2.18
AKR/J f 12.4 11.7   8 4.13 0.946 6.65, 41.1 -0.22
AKR/J m 10.7 3.43   8 1.21 0.322 4.17, 14.6 -0.13
BALB/cByJ f 37.9 5.15   8 1.82 0.136 29.7, 45.1 1.55
BALB/cByJ m 1.61 0.875   8 0.31 0.542 0.36, 2.58 -0.81
BTBR T+ Itpr3tf/J f 2.39 0.343   8 0.121 0.144 1.87, 2.84 -0.92
BTBR T+ Itpr3tf/J m 2.73 1.1   8 0.389 0.403 1.86, 4.64 -0.73
BUB/BnJ f 41.0 6.78   8 2.4 0.165 28.8, 49.1 1.77
BUB/BnJ m 49.1 8.87   8 3.14 0.181 38.0, 68.2 2.72
C3H/HeJ f 7.94 1.72   8 0.609 0.217 5.08, 10.5 -0.53
C3H/HeJ m 5.28 1.56   8 0.55 0.295 3.0, 7.95 -0.54
C57BL/10J f 8.58 3.37   8 1.19 0.393 4.51, 14.3 -0.49
C57BL/10J m 4.79 1.78   8 0.629 0.372 2.23, 7.33 -0.57
C57BL/6J f 4.89 2.89   8 1.02 0.592 1.86, 9.15 -0.75
C57BL/6J m 3.9 1.31   8 0.462 0.336 2.41, 6.54 -0.64
C57BLKS/J f 2.77 1.01   8 0.356 0.363 1.53, 4.2 -0.89
C57BLKS/J m 2.37 0.435   8 0.154 0.183 1.85, 3.29 -0.75
C57BR/cdJ f 10.5 3.35   8 1.18 0.318 7.05, 16.8 -0.36
C57BR/cdJ m 9.83 2.54   8 0.896 0.258 4.56, 12.9 -0.2
C57L/J f 3.87 0.812   8 0.287 0.21 2.6, 4.76 -0.82
C57L/J m 4.92 1.76   8 0.622 0.357 2.91, 8.25 -0.56
CAST/EiJ f 6.44 1.37   6 0.561 0.213 5.11, 8.29 -0.64
CBA/J f 5.64 1.69   8 0.596 0.299 3.3, 8.62 -0.69
CBA/J m 9.11 3.0   8 1.06 0.329 5.79, 15.2 -0.25
DBA/2J f 10.5 3.67   8 1.3 0.348 5.43, 15.5 -0.36
DBA/2J m 16.4 3.87   8 1.37 0.237 8.75, 21.4 0.29
FVB/NJ f 4.94 1.49   8 0.526 0.301 3.31, 6.93 -0.74
FVB/NJ m 6.64 1.66   8 0.588 0.251 4.35, 8.72 -0.44
KK/HlJ f 24.0 15.1   8 5.34 0.63 10.0, 49.5 0.59
KK/HlJ m 9.55 3.36   8 1.19 0.352 5.78, 15.2 -0.22
LP/J f 35.5 19.7   8 6.96 0.554 11.8, 63.6 1.39
LP/J m 45.1 20.0   8 7.06 0.443 19.5, 69.7 2.42
MOLF/EiJ f 21.8 4.03   7 1.52 0.185 17.2, 28.6 0.43
MOLF/EiJ m 21.7 4.79   8 1.7 0.221 16.4, 31.3 0.68
MRL/MpJ f 18.9 5.38   8 1.9 0.284 12.2, 29.2 0.23
MRL/MpJ m 10.4 4.06   8 1.43 0.389 5.44, 17.8 -0.16
NOD.B10Sn-H2b/J f 3.52 1.05   9 0.352 0.299 2.5, 5.84 -0.84
NOD.B10Sn-H2b/J m 5.52 1.23   7 0.464 0.222 3.88, 7.58 -0.52
NON/ShiLtJ f 27.8 4.48   8 1.58 0.161 21.9, 36.8 0.85
NON/ShiLtJ m 16.1 2.7   8 0.954 0.168 12.8, 20.1 0.27
NZO/HlLtJ f 3.89 1.05   8 0.371 0.27 2.7, 6.05 -0.82
NZO/HlLtJ m 7.36 1.97   8 0.698 0.268 5.41, 11.5 -0.38
NZW/LacJ f 30.5 9.17   8 3.24 0.301 19.0, 46.3 1.04
NZW/LacJ m 18.3 3.23   8 1.14 0.177 13.5, 21.6 0.43
P/J f 36.5 11.6   8 4.1 0.318 21.8, 62.4 1.46
P/J m 0.92 0.127   8 0.0449 0.138 0.71, 1.11 -0.86
PL/J f 1.42 0.328   7 0.124 0.23 1.02, 2.06 -0.99
PL/J m 1.83 0.48   7 0.181 0.263 0.95, 2.46 -0.79
PWD/PhJ f 6.03 4.67   8 1.65 0.774 1.31, 14.5 -0.67
PWD/PhJ m 3.36 1.27   8 0.45 0.379 1.38, 5.57 -0.68
RIIIS/J f 4.57 1.2   8 0.423 0.262 3.44, 6.9 -0.77
RIIIS/J m 7.03 1.07   8 0.38 0.153 5.56, 8.73 -0.41
SJL/J f 7.84 0.941   8 0.333 0.12 6.83, 9.87 -0.54
SJL/J m 5.99 2.48   6 1.01 0.414 3.2, 9.73 -0.48
SM/J f 4.95 2.29   16 0.573 0.463 1.56, 9.69 -0.74
SM/J m 7.17 1.4   8 0.496 0.196 4.51, 9.56 -0.4
SWR/J f 41.8 11.6   8 4.1 0.277 26.1, 66.0 1.83
SWR/J m 39.8 6.61   8 2.34 0.166 30.9, 48.2 2.03
WSB/EiJ f 1.32 0.882   8 0.312 0.671 0.45, 3.2 -1.0
WSB/EiJ m 1.47 0.456   6 0.186 0.311 1.04, 2.25 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.9 2.0839 24.9957 16.8043
129S1/SvImJ m 16.7875 2.0839 20.8832 12.6918
A/J f 48.3375 2.0839 52.4332 44.2418
A/J m 41.7625 2.0839 45.8582 37.6668
AKR/J f 12.3562 2.0839 16.452 8.2605
AKR/J m 10.6525 2.0839 14.7482 6.5568
BALB/cByJ f 37.925 2.0839 42.0207 33.8293
BALB/cByJ m 1.615 2.0839 5.7107 0.0
BTBR T+ Itpr3tf/J f 2.39 2.0839 6.4857 0.0
BTBR T+ Itpr3tf/J m 2.7288 2.0839 6.8245 0.0
BUB/BnJ f 41.0125 2.0839 45.1082 36.9168
BUB/BnJ m 49.0625 2.0839 53.1582 44.9668
C3H/HeJ f 7.9438 2.0839 12.0395 3.848
C3H/HeJ m 5.2788 2.0839 9.3745 1.183
C57BL/10J f 8.5787 2.0839 12.6745 4.483
C57BL/10J m 4.7875 2.0839 8.8832 0.6918
C57BL/6J f 4.8863 2.0839 8.982 0.7905
C57BL/6J m 3.8988 2.0839 7.9945 0.0
C57BLKS/J f 2.7688 2.0839 6.8645 0.0
C57BLKS/J m 2.3713 2.0839 6.467 0.0
C57BR/cdJ f 10.5137 2.0839 14.6095 6.418
C57BR/cdJ m 9.8325 2.0839 13.9282 5.7368
C57L/J f 3.8663 2.0839 7.962 0.0
C57L/J m 4.9238 2.0839 9.0195 0.828
CBA/J f 5.6412 2.0839 9.737 1.5455
CBA/J m 9.1075 2.0839 13.2032 5.0118
DBA/2J f 10.5275 2.0839 14.6232 6.4318
DBA/2J m 16.3688 2.0839 20.4645 12.273
FVB/NJ f 4.9425 2.0839 9.0382 0.8468
FVB/NJ m 6.6375 2.0839 10.7332 2.5418
KK/HlJ f 23.9875 2.0839 28.0832 19.8918
KK/HlJ m 9.555 2.0839 13.6507 5.4593
LP/J f 35.5125 2.0839 39.6082 31.4168
LP/J m 45.05 2.0839 49.1457 40.9543
MOLF/EiJ f 21.7571 2.2278 26.1356 17.3786
MOLF/EiJ m 21.6875 2.0839 25.7832 17.5918
MRL/MpJ f 18.95 2.0839 23.0457 14.8543
MRL/MpJ m 10.4425 2.0839 14.5382 6.3468
NOD.B10Sn-H2b/J f 3.5233 1.9647 7.3848 0.0
NOD.B10Sn-H2b/J m 5.5186 2.2278 9.8971 1.1401
NON/ShiLtJ f 27.7875 2.0839 31.8832 23.6918
NON/ShiLtJ m 16.05 2.0839 20.1457 11.9543
NZO/HlLtJ f 3.8875 2.0839 7.9832 0.0
NZO/HlLtJ m 7.3562 2.0839 11.452 3.2605
NZW/LacJ f 30.5 2.0839 34.5957 26.4043
NZW/LacJ m 18.275 2.0839 22.3707 14.1793
P/J f 36.475 2.0839 40.5707 32.3793
P/J m 0.92 2.0839 5.0157 0.0
PL/J f 1.4229 2.2278 5.8014 0.0
PL/J m 1.8257 2.2278 6.2042 0.0
PWD/PhJ f 6.0275 2.0839 10.1232 1.9318
PWD/PhJ m 3.3625 2.0839 7.4582 0.0
RIIIS/J f 4.57 2.0839 8.6657 0.4743
RIIIS/J m 7.0338 2.0839 11.1295 2.938
SJL/J f 7.8375 2.0839 11.9332 3.7418
SJL/J m 5.99 2.4062 10.7193 1.2607
SM/J f 4.9513 1.4735 7.8474 2.0551
SM/J m 7.165 2.0839 11.2607 3.0693
SWR/J f 41.7625 2.0839 45.8582 37.6668
SWR/J m 39.8125 2.0839 43.9082 35.7168
WSB/EiJ f 1.315 2.0839 5.4107 0.0
WSB/EiJ m 1.4667 2.4062 6.196 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.8438 1.4735 21.7399 15.9476
A/J both 45.05 1.4735 47.9461 42.1539
AKR/J both 11.5044 1.4735 14.4005 8.6083
BALB/cByJ both 19.77 1.4735 22.6661 16.8739
BTBR T+ Itpr3tf/J both 2.5594 1.4735 5.4555 0.0
BUB/BnJ both 45.0375 1.4735 47.9336 42.1414
C3H/HeJ both 6.6113 1.4735 9.5074 3.7151
C57BL/10J both 6.6831 1.4735 9.5792 3.787
C57BL/6J both 4.3925 1.4735 7.2886 1.4964
C57BLKS/J both 2.57 1.4735 5.4661 0.0
C57BR/cdJ both 10.1731 1.4735 13.0692 7.277
C57L/J both 4.395 1.4735 7.2911 1.4989
CBA/J both 7.3744 1.4735 10.2705 4.4783
DBA/2J both 13.4481 1.4735 16.3442 10.552
FVB/NJ both 5.79 1.4735 8.6861 2.8939
KK/HlJ both 16.7712 1.4735 19.6674 13.8751
LP/J both 40.2812 1.4735 43.1774 37.3851
MOLF/EiJ both 21.7223 1.5252 24.7201 18.7246
MRL/MpJ both 14.6962 1.4735 17.5924 11.8001
NOD.B10Sn-H2b/J both 4.521 1.4852 7.44 1.602
NON/ShiLtJ both 21.9188 1.4735 24.8149 19.0226
NZO/HlLtJ both 5.6219 1.4735 8.518 2.7258
NZW/LacJ both 24.3875 1.4735 27.2836 21.4914
P/J both 18.6975 1.4735 21.5936 15.8014
PL/J both 1.6243 1.5753 4.7204 0.0
PWD/PhJ both 4.695 1.4735 7.5911 1.7989
RIIIS/J both 5.8019 1.4735 8.698 2.9058
SJL/J both 6.9137 1.5916 10.0419 3.7856
SM/J both 6.0581 1.2761 8.5662 3.55
SWR/J both 40.7875 1.4735 43.6836 37.8914
WSB/EiJ both 1.3908 1.5916 4.519 0.0




  GWAS USING LINEAR MIXED MODELS