Project measure / variable:   Petkova1   CD4_mem_central_M06

ID, description, units MPD:24237   CD4_mem_central_M06   CD4 T cells, central memory, as percentage of total CD4 T cells   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, central memory, as percentage of total CD4 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means3.34   % 3.91   %
Median of the strain means2.56   % 3.96   %
SD of the strain means± 2.40 ± 2.28
Coefficient of variation (CV)0.720 0.585
Min–max range of strain means0.0140   –   10.2   % 0.0164   –   8.65   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 34.3635 34.3635 13.0323 0.0003
strain 30 1693.0226 56.4341 21.4025 < 0.0001
sex:strain 30 950.3043 31.6768 12.0133 < 0.0001
Residuals 435 1147.0092 2.6368


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.2 3.9   8 1.38 0.382 2.83, 14.7 2.85
129S1/SvImJ m 1.94 0.612   8 0.217 0.316 1.04, 2.99 -0.86
A/J f 2.35 0.981   8 0.347 0.418 1.04, 4.32 -0.41
A/J m 6.77 2.64   8 0.932 0.39 4.35, 11.7 1.25
AKR/J f 3.76 3.58   8 1.26 0.952 1.31, 12.2 0.17
AKR/J m 4.9 1.06   8 0.376 0.217 3.28, 6.2 0.44
BALB/cByJ f 1.03 0.145   8 0.0511 0.14 0.84, 1.3 -0.96
BALB/cByJ m 3.59 1.56   8 0.553 0.436 1.08, 5.51 -0.14
BTBR T+ Itpr3tf/J f 1.5 0.385   8 0.136 0.257 0.94, 2.2 -0.77
BTBR T+ Itpr3tf/J m 1.41 0.3   8 0.106 0.212 1.02, 1.95 -1.09
BUB/BnJ f 1.28 0.462   8 0.163 0.36 0.64, 1.89 -0.86
BUB/BnJ m 3.1 0.719   8 0.254 0.232 2.43, 4.63 -0.35
C3H/HeJ f 3.7 1.25   8 0.443 0.339 2.21, 5.65 0.15
C3H/HeJ m 5.16 1.31   8 0.464 0.255 3.25, 6.85 0.55
C57BL/10J f 5.78 1.12   8 0.395 0.193 3.27, 7.07 1.02
C57BL/10J m 5.97 2.2   8 0.778 0.369 3.22, 9.91 0.9
C57BL/6J f 7.81 0.705   8 0.249 0.0903 6.66, 8.87 1.86
C57BL/6J m 5.16 1.64   8 0.58 0.318 2.58, 6.95 0.55
C57BLKS/J f 6.81 1.55   8 0.547 0.227 4.52, 9.2 1.44
C57BLKS/J m 6.85 1.15   8 0.407 0.168 4.71, 8.15 1.29
C57BR/cdJ f 2.52 1.04   8 0.369 0.414 1.01, 3.76 -0.34
C57BR/cdJ m 5.53 1.26   8 0.446 0.228 3.75, 6.93 0.71
C57L/J f 6.06 3.12   8 1.1 0.515 2.04, 11.2 1.13
C57L/J m 4.51 2.12   8 0.75 0.47 2.37, 8.31 0.26
CAST/EiJ f 3.1 2.38   6 0.972 0.767 0.93, 6.08 -0.1
CBA/J f 4.61 1.41   8 0.5 0.307 2.53, 7.65 0.53
CBA/J m 5.96 3.48   8 1.23 0.583 2.9, 13.1 0.9
DBA/2J f 3.17 1.27   8 0.448 0.4 0.99, 4.6 -0.07
DBA/2J m 2.53 0.546   8 0.193 0.216 1.8, 3.36 -0.6
FVB/NJ f 2.25 0.643   8 0.227 0.286 1.68, 3.46 -0.45
FVB/NJ m 5.04 0.649   8 0.23 0.129 3.64, 5.82 0.5
KK/HlJ f 2.28 1.32   8 0.468 0.582 0.81, 5.08 -0.44
KK/HlJ m 0.911 0.508   8 0.18 0.558 0.25, 1.81 -1.31
LP/J f 5.68 4.07   8 1.44 0.717 1.15, 11.5 0.97
LP/J m 7.45 3.35   8 1.19 0.45 3.01, 11.9 1.55
MOLF/EiJ f 0.014 0.02   7 0.00757 1.43 -1.38
MOLF/EiJ m 0.0164 0.0173   8 0.00612 1.06 -1.7
MRL/MpJ f 1.76 0.627   8 0.222 0.357 1.07, 2.59 -0.66
MRL/MpJ m 1.76 0.289   8 0.102 0.164 1.29, 2.01 -0.94
NOD.B10Sn-H2b/J f 3.26 1.18   9 0.393 0.362 1.8, 5.25 -0.03
NOD.B10Sn-H2b/J m 3.96 1.48   7 0.56 0.374 2.18, 6.03 0.02
NON/ShiLtJ f 1.58 0.557   8 0.197 0.352 0.9, 2.58 -0.73
NON/ShiLtJ m 8.65 3.32   8 1.18 0.384 4.28, 15.4 2.08
NZO/HlLtJ f 3.49 0.759   8 0.268 0.218 2.65, 4.71 0.06
NZO/HlLtJ m 3.57 1.4   8 0.494 0.392 1.29, 5.57 -0.15
NZW/LacJ f 7.82 3.2   8 1.13 0.409 3.82, 13.5 1.86
NZW/LacJ m 4.11 0.671   8 0.237 0.163 3.05, 4.93 0.09
P/J f 1.81 0.724   8 0.256 0.399 1.08, 3.11 -0.64
P/J m 4.49 1.32   8 0.465 0.293 2.2, 6.33 0.26
PL/J f 2.48 0.405   7 0.153 0.163 1.84, 3.0 -0.36
PL/J m 2.31 0.38   7 0.143 0.164 1.72, 2.71 -0.7
PWD/PhJ f 0.127 0.0848   8 0.03 0.667 0.054, 0.31 -1.34
PWD/PhJ m 0.226 0.149   8 0.0527 0.659 0.12, 0.59 -1.61
RIIIS/J f 1.48 0.45   8 0.159 0.303 1.01, 2.31 -0.77
RIIIS/J m 0.878 0.214   8 0.0758 0.244 0.64, 1.2 -1.33
SJL/J f 0.745 0.197   8 0.0697 0.265 0.51, 1.0 -1.08
SJL/J m 7.42 1.69   6 0.69 0.228 4.66, 9.35 1.54
SM/J f 3.59 1.27   16 0.316 0.353 1.93, 6.44 0.1
SM/J m 2.85 0.44   8 0.156 0.154 2.17, 3.5 -0.46
SWR/J f 2.22 2.29   8 0.808 1.03 0.7, 7.55 -0.47
SWR/J m 1.81 0.761   8 0.269 0.42 0.77, 3.12 -0.92
WSB/EiJ f 2.61 0.36   8 0.127 0.138 2.16, 3.18 -0.3
WSB/EiJ m 2.25 0.375   6 0.153 0.166 1.7, 2.85 -0.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.225 0.5741 11.3534 9.0966
129S1/SvImJ m 1.94 0.5741 3.0684 0.8116
A/J f 2.3488 0.5741 3.4771 1.2204
A/J m 6.7688 0.5741 7.8971 5.6404
AKR/J f 3.7575 0.5741 4.8859 2.6291
AKR/J m 4.8962 0.5741 6.0246 3.7679
BALB/cByJ f 1.03 0.5741 2.1584 0.0
BALB/cByJ m 3.5925 0.5741 4.7209 2.4641
BTBR T+ Itpr3tf/J f 1.4975 0.5741 2.6259 0.3691
BTBR T+ Itpr3tf/J m 1.4112 0.5741 2.5396 0.2829
BUB/BnJ f 1.2838 0.5741 2.4121 0.1554
BUB/BnJ m 3.1013 0.5741 4.2296 1.9729
C3H/HeJ f 3.7 0.5741 4.8284 2.5716
C3H/HeJ m 5.16 0.5741 6.2884 4.0316
C57BL/10J f 5.7775 0.5741 6.9059 4.6491
C57BL/10J m 5.9675 0.5741 7.0959 4.8391
C57BL/6J f 7.81 0.5741 8.9384 6.6816
C57BL/6J m 5.16 0.5741 6.2884 4.0316
C57BLKS/J f 6.8088 0.5741 7.9371 5.6804
C57BLKS/J m 6.8463 0.5741 7.9746 5.7179
C57BR/cdJ f 2.515 0.5741 3.6434 1.3866
C57BR/cdJ m 5.525 0.5741 6.6534 4.3966
C57L/J f 6.0562 0.5741 7.1846 4.9279
C57L/J m 4.5125 0.5741 5.6409 3.3841
CBA/J f 4.6062 0.5741 5.7346 3.4779
CBA/J m 5.9638 0.5741 7.0921 4.8354
DBA/2J f 3.1675 0.5741 4.2959 2.0391
DBA/2J m 2.53 0.5741 3.6584 1.4016
FVB/NJ f 2.2487 0.5741 3.3771 1.1204
FVB/NJ m 5.0413 0.5741 6.1696 3.9129
KK/HlJ f 2.2763 0.5741 3.4046 1.1479
KK/HlJ m 0.9113 0.5741 2.0396 0.0
LP/J f 5.6787 0.5741 6.8071 4.5504
LP/J m 7.4538 0.5741 8.5821 6.3254
MOLF/EiJ f 0.014 0.6137 1.2203 0.0
MOLF/EiJ m 0.0164 0.5741 1.1447 0.0
MRL/MpJ f 1.755 0.5741 2.8834 0.6266
MRL/MpJ m 1.76 0.5741 2.8884 0.6316
NOD.B10Sn-H2b/J f 3.26 0.5413 4.3238 2.1962
NOD.B10Sn-H2b/J m 3.9571 0.6137 5.1634 2.7509
NON/ShiLtJ f 1.5838 0.5741 2.7121 0.4554
NON/ShiLtJ m 8.655 0.5741 9.7834 7.5266
NZO/HlLtJ f 3.4875 0.5741 4.6159 2.3591
NZO/HlLtJ m 3.5688 0.5741 4.6971 2.4404
NZW/LacJ f 7.8225 0.5741 8.9509 6.6941
NZW/LacJ m 4.1138 0.5741 5.2421 2.9854
P/J f 1.8137 0.5741 2.9421 0.6854
P/J m 4.4913 0.5741 5.6196 3.3629
PL/J f 2.4829 0.6137 3.6891 1.2766
PL/J m 2.31 0.6137 3.5163 1.1037
PWD/PhJ f 0.1271 0.5741 1.2555 0.0
PWD/PhJ m 0.2263 0.5741 1.3546 0.0
RIIIS/J f 1.4825 0.5741 2.6109 0.3541
RIIIS/J m 0.8775 0.5741 2.0059 0.0
SJL/J f 0.745 0.5741 1.8734 0.0
SJL/J m 7.4217 0.6629 8.7246 6.1187
SM/J f 3.5856 0.406 4.3835 2.7877
SM/J m 2.85 0.5741 3.9784 1.7216
SWR/J f 2.2162 0.5741 3.3446 1.0879
SWR/J m 1.81 0.5741 2.9384 0.6816
WSB/EiJ f 2.61 0.5741 3.7384 1.4816
WSB/EiJ m 2.2533 0.6629 3.5563 0.9504


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.0825 0.406 6.8804 5.2846
A/J both 4.5588 0.406 5.3566 3.7609
AKR/J both 4.3269 0.406 5.1248 3.529
BALB/cByJ both 2.3112 0.406 3.1091 1.5134
BTBR T+ Itpr3tf/J both 1.4544 0.406 2.2523 0.6565
BUB/BnJ both 2.1925 0.406 2.9904 1.3946
C3H/HeJ both 4.43 0.406 5.2279 3.6321
C57BL/10J both 5.8725 0.406 6.6704 5.0746
C57BL/6J both 6.485 0.406 7.2829 5.6871
C57BLKS/J both 6.8275 0.406 7.6254 6.0296
C57BR/cdJ both 4.02 0.406 4.8179 3.2221
C57L/J both 5.2844 0.406 6.0823 4.4865
CBA/J both 5.285 0.406 6.0829 4.4871
DBA/2J both 2.8488 0.406 3.6466 2.0509
FVB/NJ both 3.645 0.406 4.4429 2.8471
KK/HlJ both 1.5938 0.406 2.3916 0.7959
LP/J both 6.5663 0.406 7.3641 5.7684
MOLF/EiJ both 0.0152 0.4202 0.8411 0.0
MRL/MpJ both 1.7575 0.406 2.5554 0.9596
NOD.B10Sn-H2b/J both 3.6086 0.4092 4.4128 2.8044
NON/ShiLtJ both 5.1194 0.406 5.9173 4.3215
NZO/HlLtJ both 3.5281 0.406 4.326 2.7302
NZW/LacJ both 5.9681 0.406 6.766 5.1702
P/J both 3.1525 0.406 3.9504 2.3546
PL/J both 2.3964 0.434 3.2494 1.5435
PWD/PhJ both 0.1767 0.406 0.9746 0.0
RIIIS/J both 1.18 0.406 1.9779 0.3821
SJL/J both 4.0833 0.4385 4.9451 3.2215
SM/J both 3.2178 0.3516 3.9088 2.5268
SWR/J both 2.0131 0.406 2.811 1.2152
WSB/EiJ both 2.4317 0.4385 3.2935 1.5699




  GWAS USING LINEAR MIXED MODELS