Project measure / variable:   Jaxpheno2   pct_spleen8

ID, description, units MPD:22742   pct_spleen8   spleen weight, as percentage of body weight   [%]  at age 8wks  
Data set, strains Jaxpheno2   inbred   11 strains     sex: both     age: 8wks
Procedure organ weights
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  STRAIN COMPARISON PLOT
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Jaxpheno2 - spleen weight, as percentage of body weight at age 8wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means0.401   % 0.298   %
Median of the strain means0.406   % 0.316   %
SD of the strain means± 0.103 ± 0.0698
Coefficient of variation (CV)0.258 0.234
Min–max range of strain means0.152   –   0.526   % 0.134   –   0.370   %
Mean sample size per strain7.9   mice 8.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4225 0.4225 168.5267 < 0.0001
strain 10 0.8364 0.0836 33.3597 < 0.0001
sex:strain 10 0.1113 0.0111 4.4397 < 0.0001
Residuals 168 0.4212 0.0025


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.129P2-Apoetm1Unc/J f 0.526 0.141   5 0.0631 0.268 0.41, 0.77 1.21
B6.129P2-Apoetm1Unc/J m 0.352 0.0277   5 0.0124 0.0788 0.32, 0.39 0.77
B6D2F1/J f 0.368 0.0902   6 0.0368 0.245 0.24, 0.51 -0.32
B6D2F1/J m 0.266 0.0152   5 0.00678 0.057 0.25, 0.29 -0.47
BALB/cByJ f 0.469 0.0269   10 0.00849 0.0573 0.42, 0.5 0.65
BALB/cByJ m 0.328 0.0274   10 0.00867 0.0836 0.29, 0.39 0.42
BALB/cJ f 0.41 0.0371   10 0.0117 0.0905 0.37, 0.49 0.08
BALB/cJ m 0.316 0.0407   9 0.0136 0.129 0.27, 0.41 0.25
C3H/HeJ f 0.496 0.0826   5 0.037 0.167 0.43, 0.64 0.92
C3H/HeJ m 0.298 0.0217   5 0.0097 0.0727 0.28, 0.33 -0.01
C57BL/6J f 0.406 0.0476   15 0.0123 0.117 0.34, 0.53 0.05
C57BL/6J m 0.346 0.04   15 0.0103 0.116 0.28, 0.44 0.68
CBA/J f 0.343 0.038   10 0.012 0.111 0.3, 0.43 -0.56
CBA/J m 0.237 0.0337   15 0.0087 0.142 0.19, 0.34 -0.88
DBA/2J f 0.394 0.0785   10 0.0248 0.199 0.26, 0.51 -0.07
DBA/2J m 0.37 0.0474   15 0.0122 0.128 0.31, 0.45 1.03
FVB/NJ f 0.496 0.0195   5 0.00872 0.0393 0.47, 0.51 0.92
FVB/NJ m 0.366 0.0134   5 0.006 0.0367 0.35, 0.38 0.97
NOD.CB17-Prkdcscid/J f 0.152 0.0349   5 0.0156 0.23 0.12, 0.19 -2.41
NOD.CB17-Prkdcscid/J m 0.134 0.0114   5 0.0051 0.0851 0.12, 0.15 -2.36
NOD/ShiLtJ f 0.354 0.0729   10 0.0231 0.206 0.27, 0.5 -0.46
NOD/ShiLtJ m 0.27 0.02   10 0.00632 0.0741 0.24, 0.3 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.129P2-Apoetm1Unc/J f 0.526 0.0224 0.5702 0.4818
B6.129P2-Apoetm1Unc/J m 0.352 0.0224 0.3962 0.3078
B6D2F1/J f 0.3683 0.0204 0.4087 0.328
B6D2F1/J m 0.266 0.0224 0.3102 0.2218
BALB/cByJ f 0.469 0.0158 0.5003 0.4377
BALB/cByJ m 0.328 0.0158 0.3593 0.2967
BALB/cJ f 0.41 0.0158 0.4413 0.3787
BALB/cJ m 0.3156 0.0167 0.3485 0.2826
C3H/HeJ f 0.496 0.0224 0.5402 0.4518
C3H/HeJ m 0.298 0.0224 0.3422 0.2538
C57BL/6J f 0.406 0.0129 0.4315 0.3805
C57BL/6J m 0.346 0.0129 0.3715 0.3205
CBA/J f 0.343 0.0158 0.3743 0.3117
CBA/J m 0.2373 0.0129 0.2629 0.2118
DBA/2J f 0.394 0.0158 0.4253 0.3627
DBA/2J m 0.37 0.0129 0.3955 0.3445
FVB/NJ f 0.496 0.0224 0.5402 0.4518
FVB/NJ m 0.366 0.0224 0.4102 0.3218
NOD.CB17-Prkdcscid/J f 0.152 0.0224 0.1962 0.1078
NOD.CB17-Prkdcscid/J m 0.134 0.0224 0.1782 0.0898
NOD/ShiLtJ f 0.354 0.0158 0.3853 0.3227
NOD/ShiLtJ m 0.27 0.0158 0.3013 0.2387


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.129P2-Apoetm1Unc/J both 0.439 0.0158 0.4703 0.4077
B6D2F1/J both 0.3172 0.0152 0.3471 0.2872
BALB/cByJ both 0.3985 0.0112 0.4206 0.3764
BALB/cJ both 0.3628 0.0115 0.3855 0.3401
C3H/HeJ both 0.397 0.0158 0.4283 0.3657
C57BL/6J both 0.376 0.0091 0.394 0.358
CBA/J both 0.2902 0.0102 0.3103 0.27
DBA/2J both 0.382 0.0102 0.4022 0.3618
FVB/NJ both 0.431 0.0158 0.4623 0.3997
NOD.CB17-Prkdcscid/J both 0.143 0.0158 0.1743 0.1117
NOD/ShiLtJ both 0.312 0.0112 0.3341 0.2899




  GWAS USING LINEAR MIXED MODELS