Project measure / variable:   Hampton1   PR

ID, description, units MPD:1708   PR   interval between peak of P-wave to R-wave (PR)   [ms]  
Data set, strains Hampton1   inbred   17 strains     sex: both     age: 9-12wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Hampton1 - interval between peak of P-wave to R-wave (PR)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested17 strains17 strains
Mean of the strain means26.6   ms 24.7   ms
Median of the strain means26.9   ms 26.1   ms
SD of the strain means± 2.57 ± 4.57
Coefficient of variation (CV)0.0966 0.185
Min–max range of strain means21.9   –   30.3   ms 12.3   –   30.4   ms
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 54.4292 54.4292 11.3173 0.0009
strain 15 1544.2725 102.9515 21.4063 < 0.0001
sex:strain 15 441.9809 29.4654 6.1266 < 0.0001
Residuals 216 1038.8301 4.8094


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 30.3 2.04   8 0.72 0.0672 26.3, 32.5 1.44
129S1/SvImJ m 29.1 1.26   8 0.447 0.0434 28.0, 31.5 0.97
A/J f 28.3 1.7   8 0.602 0.0602 25.2, 30.0 0.66
A/J m 26.9 1.19   7 0.449 0.0442 25.0, 28.8 0.48
AKR/J f 25.7 3.0   8 1.06 0.117 19.2, 29.0 -0.35
AKR/J m 25.6 1.72   8 0.609 0.0673 22.8, 27.5 0.2
BALB/cJ f 27.7 1.49   7 0.564 0.0539 24.8, 29.4 0.43
BALB/cJ m 27.1 3.04   8 1.07 0.112 22.6, 31.0 0.53
BTBR T+ Itpr3tf/J f 26.9 2.51   8 0.888 0.0933 23.7, 29.9 0.12
BTBR T+ Itpr3tf/J m 30.4 1.41   8 0.5 0.0465 29.1, 33.4 1.25
C3H/HeJ f 21.9 3.79   7 1.43 0.173 15.5, 27.4 -1.83
C3H/HeJ m 23.9 1.8   8 0.638 0.0757 20.7, 26.0 -0.17
C57BL/6J f 24.0 1.57   8 0.557 0.0657 22.2, 26.8 -1.01
C57BL/6J m 26.1 2.57   8 0.907 0.0984 22.3, 28.8 0.31
CAST/EiJ f 23.9 1.14   8 0.403 0.0477 21.9, 25.1 -1.05
CAST/EiJ m 21.2 2.27   8 0.804 0.107 17.8, 24.1 -0.76
CBA/J f 23.4 3.28   8 1.16 0.14 16.9, 26.9 -1.25
CBA/J m 24.9 1.48   8 0.524 0.0596 22.7, 26.8 0.05
DBA/2J f 27.7 0.779   6 0.318 0.0282 26.8, 28.8 0.43
DBA/2J m 12.3 0.0   1   0.0 0.0 12.3, 12.3 -2.71
FVB/NJ f 23.3 2.58   7 0.975 0.11 19.5, 27.3 -1.28
FVB/NJ m 19.9 2.21   8 0.781 0.111 15.3, 23.0 -1.05
LP/J f 27.7 1.59   8 0.562 0.0574 25.0, 30.0 0.43
LP/J m 27.9 1.8   8 0.638 0.0647 25.5, 30.4 0.7
NOD/ShiLtJ f 26.4 1.98   8 0.701 0.0752 22.2, 28.2 -0.08
NOD/ShiLtJ m 26.1 0.49   8 0.173 0.0188 25.5, 26.9 0.31
NZB/BlNJ f 29.6 1.29   8 0.456 0.0436 27.6, 31.2 1.17
NZB/BlNJ m 25.8 3.33   7 1.26 0.129 20.3, 28.9 0.24
PL/J f 29.8 2.66   8 0.941 0.0894 25.0, 34.0 1.25
PL/J m 27.3 1.54   8 0.544 0.0562 24.6, 29.5 0.57
SJL/J f 29.4 2.71   8 0.957 0.092 24.8, 32.1 1.09
SJL/J m 27.6 1.1   8 0.389 0.0398 26.3, 29.2 0.64
SWR/J f 26.2 2.13   8 0.752 0.0813 23.1, 28.3 -0.16
SWR/J m 17.6 3.96   5 1.77 0.225 13.0, 22.1 -1.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 30.3125 0.7754 31.8407 28.7843
129S1/SvImJ m 29.125 0.7754 30.6532 27.5968
A/J f 28.275 0.7754 29.8032 26.7468
A/J m 26.9 0.8289 28.5337 25.2663
AKR/J f 25.6625 0.7754 27.1907 24.1343
AKR/J m 25.5875 0.7754 27.1157 24.0593
BALB/cJ f 27.6857 0.8289 29.3195 26.052
BALB/cJ m 27.1125 0.7754 28.6407 25.5843
BTBR T+ Itpr3tf/J f 26.9125 0.7754 28.4407 25.3843
BTBR T+ Itpr3tf/J m 30.4125 0.7754 31.9407 28.8843
C3H/HeJ f 21.8714 0.8289 23.5052 20.2377
C3H/HeJ m 23.85 0.7754 25.3782 22.3218
C57BL/6J f 23.975 0.7754 25.5032 22.4468
C57BL/6J m 26.0875 0.7754 27.6157 24.5593
CAST/EiJ f 23.925 0.7754 25.4532 22.3968
CAST/EiJ m 21.175 0.7754 22.7032 19.6468
CBA/J f 23.375 0.7754 24.9032 21.8468
CBA/J m 24.9 0.7754 26.4282 23.3718
FVB/NJ f 23.3429 0.8289 24.9766 21.7091
FVB/NJ m 19.875 0.7754 21.4032 18.3468
LP/J f 27.6875 0.7754 29.2157 26.1593
LP/J m 27.8875 0.7754 29.4157 26.3593
NOD/ShiLtJ f 26.3625 0.7754 27.8907 24.8343
NOD/ShiLtJ m 26.1 0.7754 27.6282 24.5718
NZB/BlNJ f 29.5875 0.7754 31.1157 28.0593
NZB/BlNJ m 25.7571 0.8289 27.3909 24.1234
PL/J f 29.775 0.7754 31.3032 28.2468
PL/J m 27.35 0.7754 28.8782 25.8218
SJL/J f 29.425 0.7754 30.9532 27.8968
SJL/J m 27.6375 0.7754 29.1657 26.1093
SWR/J f 26.175 0.7754 27.7032 24.6468
SWR/J m 17.62 0.9808 19.5531 15.6869


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 29.7188 0.5483 30.7994 28.6381
A/J both 27.5875 0.5675 28.706 26.469
AKR/J both 25.625 0.5483 26.7056 24.5444
BALB/cJ both 27.3991 0.5675 28.5177 26.2806
BTBR T+ Itpr3tf/J both 28.6625 0.5483 29.7431 27.5819
C3H/HeJ both 22.8607 0.5675 23.9793 21.7422
C57BL/6J both 25.0313 0.5483 26.1119 23.9506
CAST/EiJ both 22.55 0.5483 23.6306 21.4694
CBA/J both 24.1375 0.5483 25.2181 23.0569
FVB/NJ both 21.6089 0.5675 22.7275 20.4904
LP/J both 27.7875 0.5483 28.8681 26.7069
NOD/ShiLtJ both 26.2313 0.5483 27.3119 25.1506
NZB/BlNJ both 27.6723 0.5675 28.7909 26.5538
PL/J both 28.5625 0.5483 29.6431 27.4819
SJL/J both 28.5313 0.5483 29.6119 27.4506
SWR/J both 21.8975 0.6251 23.1296 20.6654




  GWAS USING LINEAR MIXED MODELS