Project measure / variable:   Schulz1   ratio_TLC_bw

ID, description, units MPD:1622   ratio_TLC_bw   total lung capacity to body weight   [µL/g]  
Data set, strains Schulz1   inbred   7 strains     sex: both     age: 12-14wks
Procedure ventilator
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  STRAIN COMPARISON PLOT
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Schulz1 - total lung capacity to body weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means57.6   µL/g 51.6   µL/g
Median of the strain means57.6   µL/g 50.8   µL/g
SD of the strain means± 3.75 ± 6.45
Coefficient of variation (CV)0.0651 0.125
Min–max range of strain means52.9   –   64.9   µL/g 44.6   –   63.5   µL/g
Mean sample size per strain14.6   mice 14.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1775.9 1775.9 63.5293 < 0.0001
strain 6 3979.6006 663.2668 23.727 < 0.0001
sex:strain 6 585.1487 97.5248 3.4888 0.0027
Residuals 190 5311.27 27.9541


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 58.2 5.84   15 1.51 0.1 43.1, 68.9 0.15
129S1/SvImJ m 50.8 3.79   16 0.947 0.0746 43.9, 59.1 -0.12
A/J f 57.2 5.07   16 1.27 0.0885 49.8, 69.7 -0.12
A/J m 55.8 4.09   14 1.09 0.0733 49.1, 64.2 0.66
BALB/cByJ f 57.6 3.51   15 0.906 0.0609 53.4, 65.0 -0.01
BALB/cByJ m 51.8 1.92   16 0.479 0.037 48.2, 54.9 0.04
C3H/HeJ f 64.9 7.56   13 2.1 0.117 54.6, 81.2 1.93
C3H/HeJ m 63.5 10.4   14 2.79 0.164 50.8, 86.4 1.85
C57BL/6J f 58.0 3.48   14 0.931 0.0601 50.4, 62.6 0.1
C57BL/6J m 46.1 4.43   13 1.23 0.096 34.6, 51.5 -0.85
FVB/NJ f 52.9 7.35   16 1.84 0.139 41.6, 73.8 -1.26
FVB/NJ m 44.6 4.75   13 1.32 0.106 32.9, 50.1 -1.08
SWR/J f 54.7 2.79   13 0.773 0.0509 51.5, 61.9 -0.78
SWR/J m 48.4 2.85   16 0.712 0.0588 44.3, 56.1 -0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 58.2467 1.3651 60.9394 55.5539
129S1/SvImJ m 50.8062 1.3218 53.4135 48.199
A/J f 57.2375 1.3218 59.8448 54.6302
A/J m 55.7786 1.4131 58.5659 52.9913
BALB/cByJ f 57.6467 1.3651 60.3394 54.9539
BALB/cByJ m 51.7875 1.3218 54.3948 49.1802
C3H/HeJ f 64.8538 1.4664 67.7463 61.9613
C3H/HeJ m 63.4643 1.4131 66.2516 60.677
C57BL/6J f 58.0143 1.4131 60.8016 55.227
C57BL/6J m 46.1231 1.4664 49.0156 43.2306
FVB/NJ f 52.9125 1.3218 55.5198 50.3052
FVB/NJ m 44.6308 1.4664 47.5233 41.7383
SWR/J f 54.7 1.4664 57.5925 51.8075
SWR/J m 48.4125 1.3218 51.0198 45.8052


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 54.5265 0.9501 56.4006 52.6524
A/J both 56.508 0.9675 58.4164 54.5997
BALB/cByJ both 54.7171 0.9501 56.5912 52.843
C3H/HeJ both 64.1591 1.0182 66.1675 62.1506
C57BL/6J both 52.0687 1.0182 54.0771 50.0602
FVB/NJ both 48.7716 0.9871 50.7187 46.8246
SWR/J both 51.5563 0.9871 53.5033 49.6092




  GWAS USING LINEAR MIXED MODELS