Project measure / variable:   Auwerx2   creatinine_CD

ID, description, units MPD:114675   creatinine_CD   plasma creatinine amount   [µmol/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma creatinine amount CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means10.75   µmol/L 9.9696   µmol/L
Median of the strain means11.2   µmol/L 9.28   µmol/L
SD of the strain means± 1.9417 ± 1.5738
Coefficient of variation (CV)0.1806 0.1579
Min–max range of strain means6.3   –   12.9   µmol/L 7.8667   –   11.98   µmol/L
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 28.0185 28.0185 3.0291 0.0867
strain 7 35.2635 5.0376 0.5446 0.7973
sex:strain 7 74.9139 10.702 1.157 0.3404
Residuals 62 573.4925 9.2499


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 11.2 4.0058   4 2.0029 0.3577 5.2, 13.5 0.23
129S1/SvImJ m 8.7 0.88034   5 0.3937 0.1012 7.7, 9.9 -0.81
A/J f 10.48 1.5271   5 0.68293 0.1457 8.8, 12.8 -0.14
A/J m 11.64 2.7437   5 1.227 0.2357 7.9, 13.7 1.06
C57BL/6J f 10.34 1.5582   5 0.69685 0.1507 8.2, 12.4 -0.21
C57BL/6J m 8.92 0.73959   5 0.33076 0.0829 8.1, 10.0 -0.67
CAST/EiJ f 6.3 0.0   1   0.0 0.0 6.3, 6.3 -2.29
CAST/EiJ m 7.8667 0.55076   3 0.31798 0.07 7.5, 8.5 -1.34
DBA/2J f 12.2 3.7822   5 1.6914 0.31 6.7, 16.9 0.75
DBA/2J m 10.52 1.8431   5 0.82426 0.1752 9.5, 13.8 0.35
NOD/ShiLtJ f 12.171 2.7524   7 1.0403 0.2261 7.8, 15.2 0.73
NOD/ShiLtJ m 9.28 3.4774   5 1.5551 0.3747 5.0, 13.6 -0.44
NZO/HlLtJ f 11.325 1.5327   4 0.76635 0.1353 9.9, 13.4 0.3
NZO/HlLtJ m 11.94 6.7181   5 3.0044 0.5627 8.0, 23.8 1.25
PWK/PhJ f 12.9 2.6842   5 1.2004 0.2081 10.0, 17.1 1.11
PWK/PhJ m 8.88 1.9084   5 0.85346 0.2149 6.9, 11.3 -0.69
WSB/EiJ f 9.8333 4.0004   3 2.3096 0.4068 5.8, 13.8 -0.47
WSB/EiJ m 11.98 3.2904   5 1.4715 0.2747 8.3, 15.7 1.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 11.2 1.5206806259 14.2397972577 8.1602027423
129S1/SvImJ m 8.7 1.3601381007 11.4188773224 5.9811226776
A/J f 10.48 1.3601381007 13.1988773224 7.7611226776
A/J m 11.64 1.3601381007 14.3588773224 8.9211226776
C57BL/6J f 10.34 1.3601381007 13.0588773224 7.6211226776
C57BL/6J m 8.92 1.3601381007 11.6388773224 6.2011226776
DBA/2J f 12.2 1.3601381007 14.9188773224 9.4811226776
DBA/2J m 10.52 1.3601381007 13.2388773224 7.8011226776
NOD/ShiLtJ f 12.1714285714 1.1495265028 14.4692993086 9.8735578343
NOD/ShiLtJ m 9.28 1.3601381007 11.9988773224 6.5611226776
NZO/HlLtJ f 11.325 1.5206806259 14.3647972577 8.2852027423
NZO/HlLtJ m 11.94 1.3601381007 14.6588773224 9.2211226776
PWK/PhJ f 12.9 1.3601381007 15.6188773224 10.1811226776
PWK/PhJ m 8.88 1.3601381007 11.5988773224 6.1611226776
WSB/EiJ f 9.8333333333 1.7559307375 13.3433888634 6.3232778033
WSB/EiJ m 11.98 1.3601381007 14.6988773224 9.2611226776


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.95 1.0201035755 11.9891579918 7.9108420082
A/J both 11.06 0.9617628743 12.9825365919 9.1374634081
C57BL/6J both 9.63 0.9617628743 11.5525365919 7.7074634081
DBA/2J both 11.36 0.9617628743 13.2825365919 9.4374634081
NOD/ShiLtJ both 10.7257142857 0.8904194003 12.505637305 8.9457912664
NZO/HlLtJ both 11.6325 1.0201035755 13.6716579918 9.5933420082
PWK/PhJ both 10.89 0.9617628743 12.8125365919 8.9674634081
WSB/EiJ both 10.9066666667 1.1105481088 13.1266207044 8.6867126289




  GWAS USING LINEAR MIXED MODELS