Project measure / variable:   Schoonjans1   DCA_plasma_t60_HFD

ID, description, units MPD:112731   DCA_plasma_t60_HFD   plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid deoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means40.832   ng/mL
Median of the strain means27.192   ng/mL
SD of the strain means± 30.189
Coefficient of variation (CV)0.7393
Min–max range of strain means4.753   –   120.8   ng/mL
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 141925.3302 4055.0094 4.1715 < 0.0001
Residuals 118 114705.7469 972.0826


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 65.5 29.177   5 13.048 0.4455 48.36, 117.1 0.82
BXD100 m 18.816 18.831   9 6.2769 1.0008 1.288, 66.68 -0.73
BXD11 m 4.753 6.6991   2   4.737 1.4095 0.016, 9.49 -1.2
BXD12 m 57.42 29.586   4 14.793 0.5152 22.566, 89.7 0.55
BXD27 m 38.566 27.46   5 12.281 0.712 15.194, 79.21 -0.08
BXD32 m 17.934 3.0441   4 1.5221 0.1697 14.126, 20.74 -0.76
BXD34 m 15.504 11.912   4 5.9561 0.7683 5.59, 30.398 -0.84
BXD39 m 26.383 26.837   3 15.494 1.0172 8.48, 57.24 -0.48
BXD40 m 22.529 8.7701   4 4.3851 0.3893 15.064, 33.632 -0.61
BXD43 m 15.086 6.1889   5 2.7678 0.4103 4.414, 19.268 -0.85
BXD45 m 25.084 15.613   5 6.9824 0.6224 12.054, 51.94 -0.52
BXD48 m 37.142 13.73   5 6.1404 0.3697 17.97, 55.69 -0.12
BXD48a m 64.04 25.561   4 12.78 0.3991 34.924, 85.73 0.77
BXD49 m 76.69 55.88   5 24.99 0.7287 39.054, 168.4 1.19
BXD51 m 34.076 27.842   3 16.075 0.8171 11.234, 65.09 -0.22
BXD53 m 29.78 5.1411   5 2.2992 0.1726 26.23, 38.856 -0.37
BXD55 m 26.161 2.7086   5 1.2113 0.1035 22.196, 29.762 -0.49
BXD6 m 11.303 9.4376   4 4.7188 0.835 0.00454546, 21.428 -0.98
BXD62 m 48.066 31.348   4 15.674 0.6522 19.674, 81.51 0.24
BXD63 m 110.9 44.41   5 19.861 0.4006 68.42, 168.7 2.32
BXD64 m 10.363 4.0766   5 1.8231 0.3934 4.838, 15.83 -1.01
BXD66 m 11.17 10.74   3 6.2008 0.9615 4.266, 23.544 -0.98
BXD67 m 20.789 6.3708   5 2.8491 0.3064 15.284, 31.222 -0.66
BXD69 m 101.3 77.61   4 38.806 0.7665 10.226, 167.4 2.0
BXD73 m 22.37 6.1733   3 3.5642 0.276 17.584, 29.338 -0.61
BXD75 m 68.12 42.031   4 21.015 0.617 28.39, 125.0 0.9
BXD77 m 28.002 19.201   5 8.5871 0.6857 8.636, 58.51 -0.42
BXD79 m 75.7 32.269   5 14.431 0.4263 47.994, 130.8 1.15
BXD8 m 12.105 2.6064   2   1.843 0.2153 10.262, 13.948 -0.95
BXD81 m 120.8 62.25   5 27.839 0.5151 55.22, 210.5 2.65
BXD84 m 72.89 78.37   5 35.048 1.0752 21.524, 211.1 1.06
BXD87 m 65.19 14.659   4 7.3294 0.2249 49.042, 83.54 0.81
BXD89 m 18.426 5.5914   5 2.5006 0.3035 11.938, 26.838 -0.74
BXD90 m 25.528 17.944   4 8.9722 0.7029 9.2929, 45.386 -0.51
C57BL/6J m 52.85 5.4009   2   3.819 0.1022 49.032, 56.67 0.4
DBA/2J m 18.615 8.5127   3 4.9148 0.4573 9.064, 25.403 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 65.496 13.9433324606 93.1075943342 37.8844056658
BXD100 m 18.8157777778 10.392746405 39.3962450773 -1.7646895217
BXD11 m 4.753 22.0463443743 48.4107639623 -38.9047639623
BXD12 m 57.4235 15.5891196074 88.2942009492 26.5527990508
BXD27 m 38.566 13.9433324606 66.1775943342 10.9544056658
BXD32 m 17.934 15.5891196074 48.8047009492 -12.9367009492
BXD34 m 15.504 15.5891196074 46.3747009492 -15.3667009492
BXD39 m 26.3833333333 18.0007648036 62.0297483395 -9.2630816729
BXD40 m 22.529 15.5891196074 53.3997009492 -8.3417009492
BXD43 m 15.0856 13.9433324606 42.6971943342 -12.5259943342
BXD45 m 25.0836 13.9433324606 52.6951943342 -2.5279943342
BXD48 m 37.1416 13.9433324606 64.7531943342 9.5300056658
BXD48a m 64.041 15.5891196074 94.9117009492 33.1702990508
BXD49 m 76.686 13.9433324606 104.2975943342 49.0744056658
BXD51 m 34.076 18.0007648036 69.7224150062 -1.5704150062
BXD53 m 29.78 13.9433324606 57.3915943342 2.1684056658
BXD55 m 26.1608 13.9433324606 53.7723943342 -1.4507943342
BXD6 m 11.302636365 15.5891196074 42.1733373142 -19.5680645842
BXD62 m 48.0655 15.5891196074 78.9362009492 17.1947990508
BXD63 m 110.866 13.9433324606 138.4775943342 83.2544056658
BXD64 m 10.3632 13.9433324606 37.9747943342 -17.2483943342
BXD66 m 11.17 18.0007648036 46.8164150062 -24.4764150062
BXD67 m 20.7892 13.9433324606 48.4007943342 -6.8223943342
BXD69 m 101.259 15.5891196074 132.1297009492 70.3882990508
BXD73 m 22.37 18.0007648036 58.0164150062 -13.2764150062
BXD75 m 68.1195 15.5891196074 98.9902009492 37.2487990508
BXD77 m 28.002 13.9433324606 55.6135943342 0.3904056658
BXD79 m 75.6968 13.9433324606 103.3083943342 48.0852056658
BXD8 m 12.105 22.0463443743 55.7627639623 -31.5527639623
BXD81 m 120.844 13.9433324606 148.4555943342 93.2324056658
BXD84 m 72.89 13.9433324606 100.5015943342 45.2784056658
BXD87 m 65.1905 15.5891196074 96.0612009492 34.3197990508
BXD89 m 18.4256 13.9433324606 46.0371943342 -9.1859943342
BXD90 m 25.528475 15.5891196074 56.3991759492 -5.3422259492
C57BL/6J m 52.851 22.0463443743 96.5087639623 9.1932360377
DBA/2J m 18.615 18.0007648036 54.2614150062 -17.0314150062




  GWAS USING LINEAR MIXED MODELS