Project measure / variable:   Schoonjans1   aMCA_plasma_t60_CD

ID, description, units MPD:112722   aMCA_plasma_t60_CD   plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   35 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid α-muricholic acid amount, glucose kinetic test, at 20 wks of age, after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means6.0418   ng/mL
Median of the strain means3.7833   ng/mL
SD of the strain means± 6.6142
Coefficient of variation (CV)1.0947
Min–max range of strain means1.308   –   33.503   ng/mL
Mean sample size per strain3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 32 6317.2463 197.4139 1.1761 0.2717
Residuals 90 15107.4919 167.861


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 3.351 2.6205   2   1.853 0.782 1.498, 5.204 -0.41
BXD100 m 1.7385 0.45689   4 0.22845 0.2628 1.138, 2.242 -0.65
BXD11 m 2.9455 1.6815   4 0.84076 0.5709 1.37, 4.682 -0.47
BXD12 m 15.776 15.619   2   11.044 0.99 4.732, 26.82 1.47
BXD27 m 3.8487 1.4596   4 0.72981 0.3793 2.212, 5.2568 -0.33
BXD32 m 17.272 28.02   5 12.531 1.6223 1.738, 67.13 1.7
BXD34 m 3.3652 2.3157   5 1.0356 0.6881 1.308, 6.712 -0.4
BXD40 m 16.513 19.49   4 9.7452 1.1803 3.06, 45.466 1.58
BXD43 m 1.81 0.0   1   0.0 0.0 1.81, 1.81 -0.64
BXD45 m 5.146 5.1983   3 3.0012 1.0102 1.396, 11.08 -0.14
BXD48 m 3.8232 1.6365   5 0.73184 0.428 1.788, 6.024 -0.34
BXD48a m 4.794 2.5134   4 1.2567 0.5243 1.13, 6.588 -0.19
BXD49 m 4.5013 2.7068   3 1.5628 0.6013 1.868, 7.276 -0.23
BXD51 m 1.8753 1.3414   3 0.77445 0.7153 1.004, 3.42 -0.63
BXD53 m 1.6573 0.84845   3 0.48985 0.5119 1.046, 2.626 -0.66
BXD55 m 11.995 11.347   5 5.0745 0.9459 1.646, 31.14 0.9
BXD6 m 10.728 7.3245   5 3.2756 0.6827 2.84, 19.914 0.71
BXD62 m 6.138 4.233   5 1.893 0.6896 1.984, 13.184 0.01
BXD63 m 1.308 0.0   1   0.0 0.0 1.308, 1.308 -0.72
BXD64 m 1.819 0.95726   4 0.47863 0.5263 1.186, 3.226 -0.64
BXD66 m 1.6165 0.4923   4 0.24615 0.3045 1.068, 2.216 -0.67
BXD67 m 1.513 0.42285   2   0.299 0.2795 1.214, 1.812 -0.68
BXD69 m 4.9392 5.6003   5 2.5046 1.1339 1.422, 14.612 -0.17
BXD73 m 3.742 1.3781   4 0.68905 0.3683 2.346, 4.934 -0.35
BXD75 m 5.4648 2.7915   5 1.2484 0.5108 2.686, 10.132 -0.09
BXD77 m 33.503 44.828   5 20.048 1.338 2.694, 107.3 4.15
BXD79 m 3.7833 2.2917   3 1.3231 0.6057 1.71, 6.244 -0.34
BXD8 m 2.263 1.7635   2   1.247 0.7793 1.016, 3.51 -0.57
BXD81 m 2.3113 1.31   3 0.75635 0.5668 1.318, 3.796 -0.56
BXD84 m 1.6767 0.25141   3 0.14515 0.1499 1.442, 1.942 -0.66
BXD87 m 4.4944 2.771   5 1.2392 0.6166 2.234, 9.27 -0.23
BXD89 m 3.225 0.42002   2   0.297 0.1302 2.928, 3.522 -0.43
BXD90 m 5.396 4.9695   2   3.514 0.921 1.882, 8.91 -0.1
C57BL/6J m 14.52 18.411   5 8.2335 1.2679 3.098, 46.912 1.28
DBA/2J m 2.6107 1.0524   3 0.60762 0.4031 1.75, 3.784 -0.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 3.351 9.1613596581 21.551639991 -14.849639991
BXD100 m 1.7385 6.4780595391 14.6082959596 -11.1312959596
BXD11 m 2.9455 6.4780595391 15.8152959596 -9.9242959596
BXD12 m 15.776 9.1613596581 33.976639991 -2.424639991
BXD27 m 3.8487 6.4780595391 16.7184959596 -9.0210959596
BXD32 m 17.272 5.7941525967 28.7830954489 5.7609045511
BXD34 m 3.3652 5.7941525967 14.8762954489 -8.1458954489
BXD40 m 16.5125 6.4780595391 29.3822959596 3.6427040404
BXD45 m 5.146 7.4802188375 20.0067603233 -9.7147603233
BXD48 m 3.8232 5.7941525967 15.3342954489 -7.6878954489
BXD48a m 4.794 6.4780595391 17.6637959596 -8.0757959596
BXD49 m 4.5013333333 7.4802188375 19.3620936567 -10.35942699
BXD51 m 1.8753333333 7.4802188375 16.7360936567 -12.98542699
BXD53 m 1.6573333333 7.4802188375 16.5180936567 -13.20342699
BXD55 m 11.9952 5.7941525967 23.5062954489 0.4841045511
BXD6 m 10.7284 5.7941525967 22.2394954489 -0.7826954489
BXD62 m 6.138 5.7941525967 17.6490954489 -5.3730954489
BXD64 m 1.819 6.4780595391 14.6887959596 -11.0507959596
BXD66 m 1.6165 6.4780595391 14.4862959596 -11.2532959596
BXD67 m 1.513 9.1613596581 19.713639991 -16.687639991
BXD69 m 4.9392 5.7941525967 16.4502954489 -6.5718954489
BXD73 m 3.742 6.4780595391 16.6117959596 -9.1277959596
BXD75 m 5.4648 5.7941525967 16.9758954489 -6.0462954489
BXD77 m 33.5028 5.7941525967 45.0138954489 21.9917045511
BXD79 m 3.7833333333 7.4802188375 18.6440936567 -11.07742699
BXD8 m 2.263 9.1613596581 20.463639991 -15.937639991
BXD81 m 2.3113333333 7.4802188375 17.1720936567 -12.54942699
BXD84 m 1.6766666667 7.4802188375 16.53742699 -13.1840936567
BXD87 m 4.4944 5.7941525967 16.0054954489 -7.0166954489
BXD89 m 3.225 9.1613596581 21.425639991 -14.975639991
BXD90 m 5.396 9.1613596581 23.596639991 -12.804639991
C57BL/6J m 14.52 5.7941525967 26.0310954489 3.0089045511
DBA/2J m 2.6106666667 7.4802188375 17.47142699 -12.2500936567




  GWAS USING LINEAR MIXED MODELS