Project measure / variable:   Schoonjans1   wMCA_plasma_t0_CD

ID, description, units MPD:112680   wMCA_plasma_t0_CD   plasma bile acid ω-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid ω-muricholic acid, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means76.2   ng/mL
Median of the strain means61.5   ng/mL
SD of the strain means± 57.91
Coefficient of variation (CV)0.76
Min–max range of strain means14.101   –   311.7   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 573117.8373 16374.7954 2.5136 < 0.0001
Residuals 131 853387.0826 6514.4052


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 28.064 21.259   5 9.5074 0.7575 16.956, 66.03 -0.83
BXD100 m 19.618 5.2866   5 2.3642 0.2695 11.996, 26.776 -0.98
BXD11 m 61.34 40.149   4 20.075 0.6546 39.042, 121.5 -0.26
BXD12 m 61.65 69.99   3 40.411 1.1354 15.676, 142.2 -0.25
BXD27 m 38.516 7.7306   4 3.8653 0.2007 28.614, 45.91 -0.65
BXD32 m 90.34 72.63   5 32.481 0.804 33.528, 204.2 0.24
BXD34 m 121.5 89.45   5 40.005 0.736 29.082, 241.9 0.78
BXD39 m 68.21 70.46   3 40.678 1.033 18.276, 148.8 -0.14
BXD40 m 168.8 35.293   4 17.646 0.2091 137.6, 219.5 1.6
BXD43 m 25.812 7.5224   7 2.8432 0.2914 15.208, 33.846 -0.87
BXD45 m 76.63 52.88   4 26.439 0.6901 33.426, 148.8 0.01
BXD48 m 99.93 21.82   5 9.7582 0.2184 78.77, 130.9 0.41
BXD48a m 69.44 8.0147   4 4.0073 0.1154 59.43, 78.69 -0.12
BXD49 m 311.7 377.6   5 168.9 1.2114 18.086, 883.2 4.07
BXD51 m 14.101 8.6888   5 3.8857 0.6162 3.63, 27.74 -1.07
BXD53 m 119.8 76.23   4 38.116 0.6363 33.038, 196.5 0.75
BXD55 m 46.606 38.554   5 17.242 0.8272 17.66, 110.7 -0.51
BXD6 m 157.2 102.6   5 45.906 0.6528 63.81, 295.6 1.4
BXD62 m 45.864 12.004   5 5.3685 0.2617 30.944, 62.12 -0.52
BXD63 m 27.137 3.8748   4 1.9374 0.1428 23.412, 31.714 -0.85
BXD64 m 88.45 28.558   5 12.772 0.3229 53.1, 129.8 0.21
BXD66 m 42.798 19.269   5 8.6173 0.4502 20.698, 73.2 -0.58
BXD67 m 50.35 20.828   4 10.414 0.4137 28.116, 78.28 -0.45
BXD69 m 32.593 6.0402   5 2.7013 0.1853 24.57, 39.744 -0.75
BXD73 m 122.8 87.07   4 43.535 0.709 41.814, 238.9 0.8
BXD75 m 116.5 36.623   5 16.378 0.3144 83.47, 177.1 0.7
BXD77 m 120.7 34.771   5 15.55 0.2881 71.22, 159.1 0.77
BXD79 m 70.58 36.814   5 16.464 0.5216 31.282, 121.2 -0.1
BXD8 m 45.731 23.326   5 10.432 0.5101 23.256, 79.6 -0.53
BXD81 m 96.52 115.5   3 66.67 1.1965 16.492, 228.9 0.35
BXD84 m 28.858 10.644   5 4.7599 0.3688 14.652, 38.768 -0.82
BXD87 m 135.5 101.6   5 45.438 0.7498 72.52, 316.2 1.02
BXD89 m 32.68 25.867   6 10.56 0.7915 5.434, 78.96 -0.75
BXD90 m 23.346 16.222   5 7.2548 0.6949 9.51, 50.66 -0.91
C57BL/6J m 50.82 24.416   5 10.919 0.4804 14.624, 77.85 -0.44
DBA/2J m 32.626 9.0693   4 4.5346 0.278 25.05, 45.33 -0.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 28.0644 36.095443509 99.4697974401 -43.3409974401
BXD100 m 19.618 36.095443509 91.0233974401 -51.7873974401
BXD11 m 61.3355 40.3559326821 141.1691613182 -18.4981613182
BXD12 m 61.646 46.5990171948 153.8299717049 -30.5379717049
BXD27 m 38.516 40.3559326821 118.3496613182 -41.3176613182
BXD32 m 90.3384 36.095443509 161.7437974401 18.9330025599
BXD34 m 121.5384 36.095443509 192.9437974401 50.1330025599
BXD39 m 68.208 46.5990171948 160.3919717049 -23.9759717049
BXD40 m 168.8 40.3559326821 248.6336613182 88.9663386818
BXD43 m 25.8117142857 30.5062176579 86.1602897428 -34.5368611714
BXD45 m 76.628 40.3559326821 156.4616613182 -3.2056613182
BXD48 m 99.93 36.095443509 171.3353974401 28.5246025599
BXD48a m 69.4375 40.3559326821 149.2711613182 -10.3961613182
BXD49 m 311.7392 36.095443509 383.1445974401 240.3338025599
BXD51 m 14.1008 36.095443509 85.5061974401 -57.3045974401
BXD53 m 119.7995 40.3559326821 199.6331613182 39.9658386818
BXD55 m 46.6064 36.095443509 118.0117974401 -24.7989974401
BXD6 m 157.248 36.095443509 228.6533974401 85.8426025599
BXD62 m 45.864 36.095443509 117.2693974401 -25.5413974401
BXD63 m 27.1375 40.3559326821 106.9711613182 -52.6961613182
BXD64 m 88.446 36.095443509 159.8513974401 17.0406025599
BXD66 m 42.7984 36.095443509 114.2037974401 -28.6069974401
BXD67 m 50.3505 40.3559326821 130.1841613182 -29.4831613182
BXD69 m 32.5928 36.095443509 103.9981974401 -38.8125974401
BXD73 m 122.811 40.3559326821 202.6446613182 42.9773386818
BXD75 m 116.47 36.095443509 187.8753974401 45.0646025599
BXD77 m 120.684 36.095443509 192.0893974401 49.2786025599
BXD79 m 70.5836 36.095443509 141.9889974401 -0.8217974401
BXD8 m 45.7312 36.095443509 117.1365974401 -25.6741974401
BXD81 m 96.516 46.5990171948 188.6999717049 4.3320282951
BXD84 m 28.8584 36.095443509 100.2637974401 -42.5469974401
BXD87 m 135.51 36.095443509 206.9153974401 64.1046025599
BXD89 m 32.6796666667 32.950481055 97.8635781759 -32.5042448426
BXD90 m 23.346 36.095443509 94.7513974401 -48.0593974401
C57BL/6J m 50.8236 36.095443509 122.2289974401 -20.5817974401
DBA/2J m 32.626 40.3559326821 112.4596613182 -47.2076613182




  GWAS USING LINEAR MIXED MODELS